Research map: Research progress on metabolic abnormalities in myocardial hypertrophy

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Papers in this map

  1. Cardiac Energy Metabolism in Heart Failure · Gary D. Lopaschuk · 2021 · 1412 citations · Cited by this paper
  2. High density lipoproteins and extracellular vesicles—distinct but overlapping circulating particles and their role in atherosclerosis · 2026 · Related
  3. Cardiac Metabolism in Heart Failure · Torsten Doenst · 2013 · 1133 citations · Cited by this paper
  4. In-hospital inflammatory-nutritional-renal trajectory phenotypes and 90-day readmission or mortality in patients with acute decompensated heart failure: a retrospective cohort study · 2026 · Related
  5. Cardiac Metabolism and its Interactions With Contraction, Growth, and Survival of Cardiomyocytes · Stephen C. Kolwicz · 2013 · 826 citations · Cited by this paper
  6. Cardiovascular-kidney-metabolic: Hype or a focus on front-line health? · 2025 · Related
  7. Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure · Haipeng Sun · 2016 · 555 citations · Cited by this paper
  8. ENO1 lactylation drives bevacizumab resistance through metabolic reprogramming and angiogenesis in ovarian cancer · 2026 · Related
  9. Cardiovascular Metabolomics · Robert W. McGarrah · 2018 · 445 citations · Cited by this paper
  10. Lipotoxicity as a therapeutic target in obesity and diabetic cardiomyopathy · 2024 · Related
  11. Metabolic Coordination of Physiological and Pathological Cardiac Remodeling · Andrew Gibb · 2018 · 402 citations · Cited by this paper
  12. Recent advances in cardiovascular disease research driven by metabolomics technologies in the context of systems biology · 2024 · Related
  13. The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure · Ahmad A. Cluntun · 2020 · 358 citations · Cited by this paper
  14. Lactate-lactylation in tumor angiogenesis and progression: mechanisms, biomarker potential, and therapeutic implications · 2026 · Related
  15. Myocardial Metabolomics of Human Heart Failure With Preserved Ejection Fraction · Virginia Shalkey Hahn · 2023 · 313 citations · Cited by this paper
  16. Mitochondrial quality control as a therapeutic target in cardiovascular disease: Mechanistic insights and future directions · 2025 · Related
  17. α-myosin heavy chain lactylation maintains sarcomeric structure and function and alleviates the development of heart failure · Naijin Zhang · 2023 · 293 citations · Cited by this paper
  18. Proteogenomics of Hypertrophic Cardiomyopathy Reveals Subtype-Specific Therapy · 2026 · Related
  19. Branched-chain amino acids in cardiovascular disease · Robert W. McGarrah · 2022 · 291 citations · Cited by this paper
  20. Metabolic inflexibility across heart failure phenotypes: mechanisms and type-specific therapeutic implications · 2026 · Related
  21. Cardiac-Specific Deletion of Acetyl CoA Carboxylase 2 Prevents Metabolic Remodeling During Pressure-Overload Hypertrophy · Stephen C. Kolwicz · 2012 · 290 citations · Cited by this paper
  22. The role of CD36 in cardiovascular disease · Hongyang Shu · 2020 · 284 citations · Cited by this paper
  23. Pathophysiology and Treatment of Diabetic Cardiomyopathy and Heart Failure in Patients with Diabetes Mellitus · Kazufumi Nakamura · 2022 · 271 citations · Cited by this paper
  24. NAD + Repletion Reverses Heart Failure With Preserved Ejection Fraction · Dan Tong · 2021 · 242 citations · Cited by this paper
  25. Metabolic Remodeling Promotes Cardiac Hypertrophy by Directing Glucose to Aspartate Biosynthesis · Julia Ritterhoff · 2019 · 240 citations · Cited by this paper
  26. Nicotinamide for the treatment of heart failure with preserved ejection fraction · Mahmoud Abdellatif · 2021 · 215 citations · Cited by this paper
  27. Quality assurance and quality control reporting in untargeted metabolic phenotyping: mQACC recommendations for analytical quality management · Jennifer Kirwan · 2022 · 210 citations · Cited by this paper
  28. DYRK1B-STAT3 Drives Cardiac Hypertrophy and Heart Failure by Impairing Mitochondrial Bioenergetics · Lingfang Zhuang · 2022 · 192 citations · Cited by this paper
  29. Impaired branched chain amino acid oxidation contributes to cardiac insulin resistance in heart failure · Golam Mezbah Uddin · 2019 · 185 citations · Cited by this paper
  30. YAP mediates compensatory cardiac hypertrophy through aerobic glycolysis in response to pressure overload · Toshihide Kashihara · 2022 · 185 citations · Cited by this paper
  31. Signaling Pathways Related to Oxidative Stress in Diabetic Cardiomyopathy · Meng-ling Peng · 2022 · 178 citations · Cited by this paper
  32. Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential · Thomas G. Martin · 2023 · 175 citations · Cited by this paper
  33. Indole-3-Propionic Acid Protects Against Heart Failure With Preserved Ejection Fraction · Yu-Chen Wang · 2024 · 146 citations · Cited by this paper
  34. Advances in myocardial energy metabolism: metabolic remodelling in heart failure and beyond · Qiuyu Sun · 2024 · 141 citations · Cited by this paper
  35. 2-APQC, a small-molecule activator of Sirtuin-3 (SIRT3), alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis · Peng Fei Fu · 2024 · 135 citations · Cited by this paper
  36. Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure · Danielle S. Murashige · 2022 · 109 citations · Cited by this paper
  37. Sirt5 improves cardiomyocytes fatty acid metabolism and ameliorates cardiac lipotoxicity in diabetic cardiomyopathy via CPT2 de-succinylation · Maoxiong Wu · 2024 · 102 citations · Cited by this paper
  38. SIRT6 Mitigates Heart Failure With Preserved Ejection Fraction in Diabetes · Xiaoqian Wu · 2022 · 99 citations · Cited by this paper
  39. Integrated landscape of cardiac metabolism in end-stage human nonischemic dilated cardiomyopathy · Emily L. Flam · 2022 · 96 citations · Cited by this paper

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