Research map: Antibiotic use in serious infections

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Papers in this map

  1. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 · Andrew Rhodes · 2017 · 6863 citations · Cited by this paper
  2. ПОЛІПРАГМАЗІЯ В ІНФЕКЦІЙНІЙ ПРАКТИЦІ: МЕХАНІЗМИ РЕЗИСТЕНТНОСТІ ТА СТРАТЕГІЯ ДЕЕСКАЛАЦІЇ · Роман Грицко · 2026 · Cites this paper
  3. Strategies for improving recovery of consciousness after acute brain injury · 2026 · Related
  4. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock* · Anand Kumar · 2006 · 6208 citations · Cited by this paper
  5. Personalized protein delivery in critical care: from phenotyping and endotyping to post-ICU recovery · 2026 · Related
  6. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 · Laura Evans · 2021 · 5313 citations · Cited by this paper
  7. Advances in the postoperative care of the liver transplant recipient · 2026 · Related
  8. Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050 · Mohsen Naghavi · 2024 · 3685 citations · Cited by this paper
  9. How to establish and run a national ICU benchmarking registry · 2026 · Related
  10. Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications · Larry M. Baddour · 2015 · 3250 citations · Cited by this paper
  11. Glucagon-like peptide-1 drugs, gastrointestinal function and critical illness · 2026 · Related
  12. State‐of‐the‐Art Clinical Article: Pharmacokinetic/Pharmacodynamic Parameters: Rationale for Antibacterial Dosing of Mice and Men · William A. Craig · 1998 · 2920 citations · Cited by this paper
  13. Current evidence on septic shock in patients with cirrhosis · 2026 · Related
  14. Infectious Diseases Society of America 2024 Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections · Pranita D. Tamma · 2024 · 1157 citations · Cited by this paper
  15. Preexisting malnutrition in the ICU · 2026 · Related
  16. Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper# · Mohd Hafiz Abdul-Aziz · 2020 · 1112 citations · Cited by this paper
  17. Ventilator-associated pneumonia: newer insights that can drive improved outcomes · 2026 · Related
  18. Prevalence and Outcomes of Infection Among Patients in Intensive Care Units in 2017 · Jean‐Louis Vincent · 2020 · 1073 citations · Cited by this paper
  19. Acalculous cholecystitis in the critically ill: evolving insights into diagnosis and management · 2026 · Related
  20. Efficacy and safety of cefiderocol or best available therapy for the treatment of serious infections caused by carbapenem-resistant Gram-negative bacteria (CREDIBLE-CR): a randomised, open-label, multicentre, pathogen-focused, descriptive, phase 3 trial · Matteo Bassetti · 2020 · 832 citations · Cited by this paper
  21. Clinical impact of antimicrobial de-escalation in critically ill patients: A single-center cohort study · 2026 · Related
  22. Therapeutic Monitoring of Vancomycin for Serious Methicillin-resistant Staphylococcus aureus Infections: A Revised Consensus Guideline and Review by the American Society of Health-system Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists · Michael Joseph Rybak · 2020 · 430 citations · Cited by this paper
  23. De-escalation of empirical therapy is associated with lower mortality in patients with severe sepsis and septic shock · José Garnacho‐Montero · 2013 · 393 citations · Cited by this paper
  24. Efficacy and safety of sulbactam–durlobactam versus colistin for the treatment of patients with serious infections caused by Acinetobacter baumannii–calcoaceticus complex: a multicentre, randomised, active-controlled, phase 3, non-inferiority clinical trial (ATTACK) · Keith S. Kaye · 2023 · 316 citations · Cited by this paper
  25. Inappropriate empirical antibiotic therapy for bloodstream infections based on discordant in-vitro susceptibilities: a retrospective cohort analysis of prevalence, predictors, and mortality risk in US hospitals · Sameer S. Kadri · 2020 · 288 citations · Cited by this paper
  26. WHO global research priorities for antimicrobial resistance in human health · Silvia Bertagnolio · 2024 · 219 citations · Cited by this paper
  27. Therapeutic drug monitoring-based dose optimisation of piperacillin and meropenem: a randomised controlled trial · Jan J. De Waele · 2013 · 197 citations · Cited by this paper
  28. Antimicrobial de-escalation in critically ill patients: a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP) · Alexis Tabah · 2019 · 193 citations · Cited by this paper
  29. Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial · Stefan Hagel · 2022 · 186 citations · Cited by this paper
  30. Therapeutic drug monitoring of β-lactam antibiotics in the critically ill: direct measurement of unbound drug concentrations to achieve appropriate drug exposures · Gloria Wong · 2018 · 180 citations · Cited by this paper
  31. Fast multiplex bacterial PCR of bronchoalveolar lavage for antibiotic stewardship in hospitalised patients with pneumonia at risk of Gram-negative bacterial infection (Flagship II): a multicentre, randomised controlled trial · Andrei M Darie · 2022 · 174 citations · Cited by this paper
  32. Prolonged vs Intermittent Infusions of β-Lactam Antibiotics in Adults With Sepsis or Septic Shock · Mohd Hafiz Abdul-Aziz · 2024 · 174 citations · Cited by this paper
  33. Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis · Joel M. Dulhunty · 2024 · 165 citations · Cited by this paper
  34. In critically ill patients, anti-anaerobic antibiotics increase risk of adverse clinical outcomes · Rishi Chanderraj · 2022 · 146 citations · Cited by this paper
  35. Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections · The BALANCE Investigators · 2024 · 146 citations · Cited by this paper
  36. Effect of Cefepime/Enmetazobactam vs Piperacillin/Tazobactam on Clinical Cure and Microbiological Eradication in Patients With Complicated Urinary Tract Infection or Acute Pyelonephritis · Keith S. Kaye · 2022 · 134 citations · Cited by this paper
  37. Model-informed precision dosing of beta-lactam antibiotics and ciprofloxacin in critically ill patients: a multicentre randomised clinical trial · Tim M. J. Ewoldt · 2022 · 127 citations · Cited by this paper
  38. Aztreonam–avibactam versus meropenem for the treatment of serious infections caused by Gram-negative bacteria (REVISIT): a descriptive, multinational, open-label, phase 3, randomised trial · Yehuda Carmeli · 2024 · 126 citations · Cited by this paper
  39. Executive Summary: Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026 · Hallie C. Prescott · 2026 · 124 citations · Cited by this paper

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