Research map: Loss of the Coronary Artery Disease Risk Gene LMOD1 in Vascular Smooth Muscle Cells Triggers Rapid-Onset Coronary Atherosclerosis

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  1. Inflammation in atherosclerosis · Peter Libby · 2002 · 8294 citations · Cited by this paper
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  17. ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. · Yutaka Nakashima · 1994 · 1702 citations · Cited by this paper
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  19. The Response-to-Retention Hypothesis of Early Atherogenesis · Kevin Jon Williams · 1995 · 1421 citations · Cited by this paper
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  22. Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis · Robert C. Wirka · 2019 · 937 citations · Cited by this paper
  23. G12-G13–LARG–mediated signaling in vascular smooth muscle is required for salt-induced hypertension · Angela Wirth · 2007 · 702 citations · Cited by this paper
  24. Single-Cell Genomics Reveals a Novel Cell State During Smooth Muscle Cell Phenotypic Switching and Potential Therapeutic Targets for Atherosclerosis in Mouse and Human · Huize Pan · 2020 · 655 citations · Cited by this paper
  25. Accelerated Atherosclerosis, Aortic Aneurysm Formation, and Ischemic Heart Disease in Apolipoprotein E/Endothelial Nitric Oxide Synthase Double-Knockout Mice · Peter Kuhlencordt · 2001 · 635 citations · Cited by this paper
  26. Serum response factor: toggling between disparate programs of gene expression · Joseph M. Miano · 2003 · 607 citations · Cited by this paper
  27. Transdifferentiation of Vascular Smooth Muscle Cells to Macrophage-Like Cells During Atherogenesis · Susanne C. Feil · 2014 · 591 citations · Cited by this paper
  28. Smooth muscle cell fate and plasticity in atherosclerosis · Sima Allahverdian · 2018 · 532 citations · Cited by this paper
  29. Cell proliferation in human coronary arteries. · David J. Gordon · 1990 · 531 citations · Cited by this paper
  30. Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023 · Mohsen Naghavi · 2025 · 508 citations · Cited by this paper
  31. Extensive Proliferation of a Subset of Differentiated, yet Plastic, Medial Vascular Smooth Muscle Cells Contributes to Neointimal Formation in Mouse Injury and Atherosclerosis Models · Joel Chappell · 2016 · 466 citations · Cited by this paper
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  33. Large-scale genome-wide association study of coronary artery disease in genetically diverse populations · Catherine Tcheandjieu · 2022 · 377 citations · Cited by this paper
  34. Smooth Muscle Cells Contribute the Majority of Foam Cells in ApoE (Apolipoprotein E)-Deficient Mouse Atherosclerosis · Ying Wang · 2019 · 366 citations · Cited by this paper
  35. Human smooth muscle myosin heavy chain isoforms as molecular markers for vascular development and atherosclerosis. · Masanori Aikawa · 1993 · 343 citations · Cited by this paper
  36. Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure · Rita Holtwick · 2002 · 341 citations · Cited by this paper
  37. Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms · CARDIoGRAMplusC4D · 2017 · 330 citations · Cited by this paper
  38. Fate and State of Vascular Smooth Muscle Cells in Atherosclerosis · Joseph M. Miano · 2021 · 328 citations · Cited by this paper
  39. Induction of Atherosclerosis in Mice and Hamsters Without Germline Genetic Engineering · Martin Mæng Bjørklund · 2014 · 320 citations · Cited by this paper

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