Research map: Hereditary Angioedema: On-demand Treatment and Long-term Prophylaxis – A Global Reality

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Papers in this map

  1. Hereditary and Acquired C1-Inhibitor Deficiency · Angelo Agostoni · 1992 · 616 citations · Cited by this paper
  2. CD40L and IL-4 lymph node-associated signals protect B cells from rituximab-induced ADCC via KIR and NKG2A · 2026 · Related
  3. Treatment of Hereditary Angioedema with Danazol · Jeffrey A. Gelfand · 1976 · 606 citations · Cited by this paper
  4. Docosahexaenoic acid mitigates experimental autoimmune prostatitis by inhibiting Th17 cell differentiation via the PPARγ/NF-κB/IL-17A pathway · 2025 · Related
  5. Icatibant, a New Bradykinin-Receptor Antagonist, in Hereditary Angioedema · Marco Cicardi · 2010 · 564 citations · Cited by this paper
  6. BAFF-R Expression as a Potential Biomarker Associated with COVID-19 Vaccine Non-Responsiveness in Antibody-Deficient Patients · 2025 · Related
  7. Nanofiltered C1 Inhibitor Concentrate for Treatment of Hereditary Angioedema · Bruce L. Zuraw · 2010 · 410 citations · Cited by this paper
  8. PSMB8 stratifies therapy response in eosinophilic esophagitis · 2026 · Related
  9. US HAEA Medical Advisory Board 2020 Guidelines for the Management of Hereditary Angioedema · Paula Jane Busse · 2020 · 374 citations · Cited by this paper
  10. Vitamin A deficiency enhances susceptibility to experimental autoimmune pancreatitis through activation of CD4+ T cells expressing CXCR3 and secreting CCL25 · 2025 · Related
  11. Efficacy of human C1 esterase inhibitor concentrate compared with placebo in acute hereditary angioedema attacks · Timothy Craig · 2009 · 343 citations · Cited by this paper
  12. Discovery and Phase 1 study of a novel monoclonal antibody against human IL-1β for the treatment of IL-1β-mediated diseases · 2025 · Related
  13. Hereditary Angioedema · Ugochukwu C. Nzeako · 2001 · 339 citations · Cited by this paper
  14. Clinical, genetic, and functional characterization of novel NFKB1 variants in Chinese patients with primary immunodeficiency · 2026 · Related
  15. Ecallantide for the Treatment of Acute Attacks in Hereditary Angioedema · Marco Cicardi · 2010 · 313 citations · Cited by this paper
  16. The pathophysiology of hemophagocytic lympho-histiocytosis (HLH) syndrome and insights from animal models · 2025 · Related
  17. Effect of Lanadelumab Compared With Placebo on Prevention of Hereditary Angioedema Attacks · Aleena Banerji · 2018 · 310 citations · Cited by this paper
  18. PD-1 engagement and circulating Th17 effector activity during secukinumab treatment in plaque psoriasis · 2026 · Related
  19. Tranexamic Acid Therapy in Hereditary Angioneurotic Edema · Albert L. Sheffer · 1972 · 249 citations · Cited by this paper
  20. Immunological dysfunction associated with SARS-CoV-2 persistence in immunocompromised patients · 2026 · Related
  21. Prevention of Hereditary Angioedema Attacks with a Subcutaneous C1 Inhibitor · Hilary J Longhurst · 2017 · 238 citations · Cited by this paper
  22. Randomized placebo-controlled trial of the bradykinin B2 receptor antagonist icatibant for the treatment of acute attacks of hereditary angioedema: the FAST-3 trial · William R. Lumry · 2011 · 230 citations · Cited by this paper
  23. Recombinant human C1-inhibitor for the treatment of acute angioedema attacks in patients with hereditary angioedema · Bruce L. Zuraw · 2010 · 221 citations · Cited by this paper
  24. Oral once-daily berotralstat for the prevention of hereditary angioedema attacks: A randomized, double-blind, placebo-controlled phase 3 trial · Bruce L. Zuraw · 2020 · 174 citations · Cited by this paper
  25. The international WAO/EAACI guideline for the management of hereditary angioedema – The 2021 revision and update · Marcus Maurer · 2022 · 160 citations · Cited by this paper
  26. Fresh frozen plasma for the treatment of hereditary angioedema · Michael J. Prematta · 2007 · 153 citations · Cited by this paper
  27. Hereditary angioedema with C1 inhibitor deficiency: delay in diagnosis in Europe · Andrea Zanichelli · 2013 · 153 citations · Cited by this paper
  28. EDEMA4: a phase 3, double-blind study of subcutaneous ecallantide treatment for acute attacks of hereditary angioedema · Robyn J. Levy · 2010 · 149 citations · Cited by this paper
  29. C1 esterase inhibitor concentrate in 1085 Hereditary Angioedema attacks - final results of the I.M.P.A.C.T.2 study · Timothy Craig · 2011 · 143 citations · Cited by this paper
  30. Efficacy and safety of garadacimab, a factor XIIa inhibitor for hereditary angioedema prevention (VANGUARD): a global, multicentre, randomised, double-blind, placebo-controlled, phase 3 trial · Timothy Craig · 2023 · 126 citations · Cited by this paper
  31. Long‐term prevention of hereditary angioedema attacks with lanadelumab: The HELP OLE Study · Aleena Banerji · 2021 · 108 citations · Cited by this paper
  32. Recombinant human C1-esterase inhibitor relieves symptoms of hereditary angioedema attacks: phase 3, randomized, placebo-controlled trial · Marc A. Riedl · 2014 · 89 citations · Cited by this paper
  33. A UK national audit of hereditary and acquired angioedema · Stephen R.A. Jolles · 2013 · 85 citations · Cited by this paper
  34. Efficacy and Safety of Donidalorsen for Hereditary Angioedema · Marc A. Riedl · 2024 · 77 citations · Cited by this paper
  35. Oral Sebetralstat for On-Demand Treatment of Hereditary Angioedema Attacks · Marc A. Riedl · 2024 · 68 citations · Cited by this paper
  36. Evaluation of Drug Trials in High-, Middle-, and Low-Income Countries and Local Commercial Availability of Newly Approved Drugs · Jennifer E. Miller · 2021 · 62 citations · Cited by this paper
  37. Mitigating Disparity in Health-care Resources Between Countries for Management of Hereditary Angioedema · Ankur Kumar Jindal · 2021 · 41 citations · Cited by this paper
  38. Fresh frozen plasma for on-demand hereditary angioedema treatment in South Africa and Iran · Nicole Wentzel · 2019 · 38 citations · Cited by this paper
  39. Uncovering the true burden of hereditary angioedema due to C1-inhibitor deficiency: A focus on the Asia-Pacific region · Daisuke Honda · 2023 · 34 citations · Cited by this paper

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