Research map: High degree of remission in pediatric severe asthma patients treated with biologics in a real-world setting

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  1. International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma · Kian Fan Chung · 2013 · 3994 citations · Cited by this paper
  2. The definition of response and inadequate response to topical corticosteroid treatment in atopic dermatitis and related skin inflammatory diseases: A GA2LEN ADCARE statement paper · 2026 · Related
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  7. Benralizumab, an anti-interleukin-5 receptor α monoclonal antibody, as add-on treatment for patients with severe, uncontrolled, eosinophilic asthma (CALIMA): a randomised, double-blind, placebo-controlled phase 3 trial · J. Mark FitzGerald · 2016 · 1412 citations · Cited by this paper
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  9. Efficacy and safety of benralizumab for patients with severe asthma uncontrolled with high-dosage inhaled corticosteroids and long-acting β2-agonists (SIROCCO): a randomised, multicentre, placebo-controlled phase 3 trial · Eugene R. Bleecker · 2016 · 1411 citations · Cited by this paper
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  11. Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma · Klaus Friedrich Rabe · 2018 · 1195 citations · Cited by this paper
  12. Comprehensive proteomic analysis reveals SPRR3 as an early predictive biomarker for postoperative recurrence in pediatric chronic rhinosinusitis with nasal polyps · 2026 · Related
  13. Development and cross-sectional validation of the Childhood Asthma Control Test · Andrew H. Liu · 2007 · 995 citations · Cited by this paper
  14. Overview of allergic disease: Pathogenesis of allergic inflammation – WAO White Book on Allergy 2026 – 2.1 · 2026 · Related
  15. Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma · Michael J. McGeachie · 2016 · 618 citations · Cited by this paper
  16. Hereditary angioedema and the gastrointestinal tract · 2026 · Related
  17. Efficacy of mepolizumab add-on therapy on health-related quality of life and markers of asthma control in severe eosinophilic asthma (MUSCA): a randomised, double-blind, placebo-controlled, parallel-group, multicentre, phase 3b trial · Geoffrey Lowell Chupp · 2017 · 603 citations · Cited by this paper
  18. Machine learning-based MPO and Lp-PLA2 profiling reveals asthma-predominant inflammatory signature in asthma-COPD overlap · 2026 · Related
  19. Efficacy of a House Dust Mite Sublingual Allergen Immunotherapy Tablet in Adults With Allergic Asthma · Johann Christian Virchow Jr. · 2016 · 437 citations · Cited by this paper
  20. PROPHYLAXIS OF SUMMER HAY-FEVER AND ASTHMA · A. W. Frankland · 1954 · 298 citations · Cited by this paper
  21. Efficacy of Tezepelumab in Severe, Uncontrolled Asthma: Pooled Analysis of the PATHWAY and NAVIGATOR Clinical Trials · Jonathan Corren · 2023 · 184 citations · Cited by this paper
  22. Mepolizumab for urban children with exacerbation-prone eosinophilic asthma in the USA (MUPPITS-2): a randomised, double-blind, placebo-controlled, parallel-group trial · Daniel J. Jackson · 2022 · 161 citations · Cited by this paper
  23. Advances in understanding and reducing the burden of severe asthma in children · Marielle W. H. Pijnenburg · 2020 · 160 citations · Cited by this paper
  24. Exploring Definitions and Predictors of Severe Asthma Clinical Remission after Biologic Treatment in Adults · Luis Pérez de Llano · 2024 · 137 citations · Cited by this paper
  25. Airway Responsiveness in Mild to Moderate Childhood Asthma · Kelan G. Tantisira · 2008 · 131 citations · Cited by this paper
  26. Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma · Mark Daniel DeBoer · 2018 · 125 citations · Cited by this paper
  27. Severe Asthma in Children · Sima K. Ramratnam · 2017 · 124 citations · Cited by this paper
  28. Housing and asthma disparities · Tyra C. Bryant-Stephens · 2021 · 117 citations · Cited by this paper
  29. Asthma exacerbations are associated with a decline in lung function: a longitudinal population-based study · Seyi Soremekun · 2022 · 109 citations · Cited by this paper
  30. Biologics in the treatment of asthma in children and adolescents · Leonard B. Bacharier · 2023 · 106 citations · Cited by this paper
  31. Asthma Exacerbations Associated with Lung Function Decline in Patients with Severe Eosinophilic Asthma · Héctor Ortega · 2018 · 92 citations · Cited by this paper
  32. Progression of Irreversible Airflow Limitation in Asthma: Correlation with Severe Exacerbations · Kazuto Matsunaga · 2015 · 82 citations · Cited by this paper
  33. Childhood Respiratory Risk Factor Profiles and Middle-Age Lung Function: A Prospective Cohort Study from the First to Sixth Decade · Dinh Bui · 2018 · 72 citations · Cited by this paper
  34. Endotype of allergic asthma with airway obstruction in urban children · Matthew C. Altman · 2021 · 71 citations · Cited by this paper
  35. Severe asthma during childhood and adolescence: A longitudinal study · Kristie R. Ross · 2019 · 70 citations · Cited by this paper
  36. Predicting the benefits of type-2 targeted anti-inflammatory treatment with the prototype Oxford Asthma Attack Risk Scale (ORACLE) · Simon Couillard · 2022 · 55 citations · Cited by this paper
  37. Determinants of lung function across childhood in the Severe Asthma Research Program (SARP) 3 · Jonathan M. Gaffin · 2022 · 32 citations · Cited by this paper
  38. Prospective, Single-Arm, Longitudinal Study of Biomarkers in Real-World Patients with Severe Asthma · Roland Buhl · 2020 · 25 citations · Cited by this paper
  39. Clinical Implications of Longitudinal Blood Eosinophil Counts in Patients With Severe Asthma · Eugene R. Bleecker · 2023 · 20 citations · Cited by this paper

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