Research map: Beyond one drug–one target: AI-guided discovery of multi-target antiviral therapeutics
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Papers in this map
Highly accurate protein structure prediction with AlphaFold
· John Jumper · 2021 · 47614 citations · Cited by this paper
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· David Scott Wishart · 2007 · 2953 citations · Cited by this paper
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· Alex Bateman · 2024 · 2450 citations · Cited by this paper
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· Luca Pinzi · 2019 · 2386 citations · Cited by this paper
Fusion protein linkers: Property, design and functionality
· Xiaoying Chen · 2012 · 2172 citations · Cited by this paper
AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences
· Mihály Váradi · 2023 · 2140 citations · Cited by this paper
Why 90% of clinical drug development fails and how to improve it?
· Duxin Sun · 2022 · 1758 citations · Cited by this paper
Interferon-stimulated genes and their antiviral effector functions
· John W. Schoggins · 2011 · 1356 citations · Cited by this paper
Computational approaches streamlining drug discovery
· Anastasiia Sadybekov · 2023 · 1300 citations · Cited by this paper
Target identification and mechanism of action in chemical biology and drug discovery
· Monica Schenone · 2013 · 1130 citations · Cited by this paper
Understanding of Machine Learning with Deep Learning: Architectures, Workflow, Applications and Future Directions
· Mohammad Mustafa Taye · 2023 · 1050 citations · Cited by this paper
Artificial Intelligence in Pharmaceutical Technology and Drug Delivery Design
· Lalitkumar K. Vora · 2023 · 1049 citations · Cited by this paper
Cytochrome P450 Enzymes and Drug Metabolism in Humans
· Mingzhe Zhao · 2021 · 1046 citations · Cited by this paper
Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications
· Javad Sharifi‐Rad · 2020 · 1035 citations · Cited by this paper
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· Rafael Sanjuán · 2016 · 1002 citations · Cited by this paper
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
· Laura Riva · 2020 · 864 citations · Cited by this paper
The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets
· Thomas P. Peacock · 2021 · 813 citations · Cited by this paper
A Structure-Based Drug Discovery Paradigm
· Maria Batool · 2019 · 769 citations · Cited by this paper
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· Adib Bin Rashid · 2024 · 737 citations · Cited by this paper
A perspective on multi‐target drug discovery and design for complex diseases
· Rona Ruth Ramsay · 2018 · 734 citations · Cited by this paper
A Review on Applications of Computational Methods in Drug Screening and Design
· Xiaoqian Lin · 2020 · 726 citations · Cited by this paper
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