Research map: Novel 3,3′-diindolylmethane derivatives as multi-pathway modulators: targeting estrogen-dependent and independent breast cancer carcinogenesis

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  1. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays · Tim R. Mosmann · 1983 · 56229 citations · Cited by this paper
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  13. Estrogen receptor-dependent and independent mechanisms of breast cancer carcinogenesis · Wei Yue · 2012 · 230 citations · Cited by this paper
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  15. Pharmacokinetics and Tissue Disposition of Indole-3-carbinol and Its Acid Condensation Products after Oral Administration to Mice · Mark J. Anderton · 2004 · 220 citations · Cited by this paper
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  21. Mechanisms of estrogen carcinogenesis: The role of E2/E1–quinone metabolites suggests new approaches to preventive intervention – A review · James D. Yager · 2014 · 141 citations · Cited by this paper
  22. Expression of cytochrome P450 CYP1B1 in breast cancer · Judith McKay · 1995 · 135 citations · Cited by this paper
  23. Estrogens and the risk of breast cancer: A narrative review of literature · Khayry Al‐Shami · 2023 · 130 citations · Cited by this paper
  24. CYP1B1 Enhances Cell Proliferation and Metastasis through Induction of EMT and Activation of Wnt/β-Catenin Signaling via Sp1 Upregulation · Yeo‐Jung Kwon · 2016 · 121 citations · Cited by this paper
  25. Indoles Derived From Glucobrassicin: Cancer Chemoprevention by Indole-3-Carbinol and 3,3'-Diindolylmethane · David E. J. Williams · 2021 · 94 citations · Cited by this paper
  26. Low Concentrations of Diindolylmethane, a Metabolite of Indole-3-Carbinol, Protect against Oxidative Stress in a BRCA1-Dependent Manner · Saijun Fan · 2009 · 92 citations · Cited by this paper
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  28. Putative Cancer Chemopreventive Agents of Dietary Origin—How Safe Are They? · Richard D. Verschoyle · 2007 · 76 citations · Cited by this paper
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  30. A randomized, placebo-controlled trial of diindolylmethane for breast cancer biomarker modulation in patients taking tamoxifen · Cynthia A. Thomson · 2017 · 67 citations · Cited by this paper
  31. 3,3′-Diindolylmethane and indole-3-carbinol: potential therapeutic molecules for cancer chemoprevention and treatment via regulating cellular signaling pathways · Octavio Daniel Reyes‐Hernández · 2023 · 66 citations · Cited by this paper
  32. Flavonoids and Naphthoflavonoids: Wider Roles in the Modulation of Cytochrome P450 Family 1 Enzymes · Jinyun Dong · 2016 · 60 citations · Cited by this paper
  33. Selective delivery of curcumin to breast cancer cells by self-targeting apoferritin nanocages with pH-responsive and low toxicity · Peng Ji · 2022 · 59 citations · Cited by this paper
  34. Indole-3-carbinol and its N-alkoxy derivatives preferentially target ER α -positive breast cancer cells · Joseph A. Caruso · 2014 · 57 citations · Cited by this paper
  35. Role of Medicinal plant‐derived Nutraceuticals as a potential target for the treatment of breast cancer · Khalid Saad Alharbi · 2022 · 55 citations · Cited by this paper
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  38. Breast Cancer Risk Associated with Estrogen Exposure and Truncating Mutation Location in BRCA1/2 Carriers · Julie Lecarpentier · 2015 · 48 citations · Cited by this paper
  39. Modulation of CYP19 expression by cabbage juices and their active components: indole-3-carbinol and 3,3′-diindolylmethene in human breast epithelial cell lines · Barbara E. Licznerska · 2012 · 44 citations · Cited by this paper

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