Research map: Mathematical model for thyroid hormone regulation in foetal rat brain

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  1. Approximate Bayesian computation scheme for parameter inference and model selection in dynamical systems · Tina Toni · 2008 · 1628 citations · Cited by this paper
  2. O-QT assistant: a multi-agent AI system for streamlined chemical hazard assessment and read-across analysis using the OECD QSAR toolbox API · 2025 · Related
  3. Deiodinases: implications of the local control of thyroid hormone action · Antonio Carlos Bianco · 2006 · 852 citations · Cited by this paper
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  5. Database for mRNA Half-Life of 19 977 Genes Obtained by DNA Microarray Analysis of Pluripotent and Differentiating Mouse Embryonic Stem Cells · L. V. Sharova · 2008 · 636 citations · Cited by this paper
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  7. Influence of maternal thyroid hormones during gestation on fetal brain development · Nora K. Moog · 2015 · 481 citations · Cited by this paper
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  9. Quasi-Equilibrium Pharmacokinetic Model for Drugs Exhibiting Target-Mediated Drug Disposition · Donald E. Mager · 2005 · 231 citations · Cited by this paper
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  11. Evaluating Chemicals for Thyroid Disruption: Opportunities and Challenges with in Vitro Testing and Adverse Outcome Pathway Approaches · Pamela D. Noyes · 2019 · 205 citations · Cited by this paper
  12. A weighted-likelihood framework for class imbalance in Bayesian prediction models · 2026 · Related
  13. Thyroidal and peripheral production of 3,5,3'-triiodothyronine in humans by multicompartmental analysis · ALESSANDRO PILO · 1990 · 189 citations · Cited by this paper
  14. Modeling molecular level mechanisms of oxidative stress generation induced by agrochemicals in CKDu initiation · 2025 · Related
  15. Type 3 lodothyronine deiodinase: cloning, in vitro expression, and functional analysis of the placental selenoenzyme. · Domenico Salvatore · 1995 · 187 citations · Cited by this paper
  16. Finding optimal designs for estimating hormesis effect sizes · 2026 · Related
  17. Thyroid hormone regulated genes in cerebral cortex development · Juan Bernal · 2016 · 153 citations · Cited by this paper
  18. Revisiting the Threshold of Toxicological Concern: a computational framework for structural classification, cross-scheme comparison and opportunities for refinement · 2026 · Related
  19. Deiodinases and the Three Types of Thyroid Hormone Deiodination Reactions · Laura Sabatino · 2021 · 150 citations · Cited by this paper
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  21. Thyroid Hormone Action: Astrocyte–Neuron Communication · Beatriz Morte · 2014 · 107 citations · Cited by this paper
  22. Type 2 deiodinase at the crossroads of thyroid hormone action · Rafael Arrojo e Drigo · 2011 · 93 citations · Cited by this paper
  23. Lack of Effect of Thyroid Hormone on Late Fetal Rat Brain Development* · Harold L. Schwartz · 1997 · 85 citations · Cited by this paper
  24. Studies of the Hormonal Regulation of Type 2 5′-Iodothyronine Deiodinase Messenger Ribonucleic Acid in Pituitary Tumor Cells Using Semiquantitative Reverse Transcription-Polymerase Chain Reaction**This work was supported by NIH Grant DK-36256. · Sung-Woo Kim · 1998 · 85 citations · Cited by this paper
  25. The Significance of Thyroid Hormone Transporters in the Brain · Juan Bernal · 2005 · 65 citations · Cited by this paper
  26. Evaluation of Perturbations in Serum Thyroid Hormones During Human Pregnancy Due to Dietary Iodide and Perchlorate Exposure Using a Biologically Based Dose-Response Model · Annie Lumen · 2013 · 64 citations · Cited by this paper
  27. Thyroxine Inner Ring Monodeiodinating Activity in Fetal Tissues of the Rat · Tien‐Shang Huang · 1988 · 61 citations · Cited by this paper
  28. Human relevance of follicular thyroid tumors in rodents caused by non-genotoxic substances · Ruediger Bartsch · 2018 · 57 citations · Cited by this paper
  29. Isoform-specific 3,5,3'-triiodothyronine receptor binding capacity and messenger ribonucleic acid content in rat adenohypophysis: effect of thyroidal state and comparison with extrapituitary tissues. · Sean Ercan-Fang · 1996 · 55 citations · Cited by this paper
  30. A review of species differences in the control of, and response to, chemical-induced thyroid hormone perturbations leading to thyroid cancer · John Reginald Foster · 2021 · 50 citations · Cited by this paper
  31. Multiscale modelling of drug transport and metabolism in liver spheroids · Joseph Leedale · 2020 · 48 citations · Cited by this paper
  32. Thyroid Hormone Disruption in the Fetal and Neonatal Rat: Predictive Hormone Measures and Bioindicators of Hormone Action in the Developing Cortex · Katherine L O’Shaughnessy · 2018 · 47 citations · Cited by this paper
  33. Transcriptional Activation of Type III Inner Ring Deiodinase by Growth Factors in Cultured Rat Brown Adipocytes* · Arturo Hernández · 1998 · 40 citations · Cited by this paper
  34. Genomic imprinting of the type 3 thyroid hormone deiodinase gene: Regulation and developmental implications · Marika Charalambous · 2012 · 35 citations · Cited by this paper
  35. Evidence for a role of the type III-iodothyronine deiodinase in the regulation of 3,5,3'-triiodothyronine content in the human central nervous system · Ferruccio Santini · 2001 · 34 citations · Cited by this paper
  36. The Challenges and Complexities of Thyroid Hormone Replacement · Shayri M. Kansagra · 2010 · 24 citations · Cited by this paper
  37. Feasibility study for a downsized comparative thyroid assay with measurement of brain thyroid hormones and histopathology in rats: Case study with 6-propylthiouracil and sodium phenobarbital at high dose · Kenta Minami · 2022 · 18 citations · Cited by this paper
  38. Mechanistic Computational Model for Extrapolating In Vitro Thyroid Peroxidase (TPO) Inhibition Data to Predict Serum Thyroid Hormone Levels in Rats · Sakshi Handa · 2021 · 14 citations · Cited by this paper

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