Research map: Neoadjuvant Chemotherapy Versus Upfront Surgery for cT2N1 or cT3a ‐ bN0 ‐1 Middle‐High Rectal Cancer

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  1. Preoperative Versus Postoperative Chemoradiotherapy for Locally Advanced Rectal Cancer: Results of the German CAO/ARO/AIO-94 Randomized Phase III Trial After a Median Follow-Up of 11 Years · Rolf Sauer · 2012 · 2153 citations · Cited by this paper
  2. Helicobacter pylori Infection and the Risk of Biliary Tract and Pancreatic Cancers: Subsite‐Specific Associations in a Japanese Population · 2026 · Related
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  5. Preoperative High-resolution Magnetic Resonance Imaging Can Identify Good Prognosis Stage I, II, and III Rectal Cancer Best Managed by Surgery Alone · Fiona G. M. Taylor · 2011 · 662 citations · Cited by this paper
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  11. Preoperative Chemotherapy for Operable Colon Cancer: Mature Results of an International Randomized Controlled Trial · Dion G. Morton · 2023 · 480 citations · Cited by this paper
  12. Obesity‐Driven Early‐Onset Colorectal Cancer: Mechanistic Insights and Emerging Clinical Implications · 2026 · Related
  13. Tumor Regression Grading After Preoperative Chemoradiotherapy for Locally Advanced Rectal Carcinoma Revisited: Updated Results of the CAO/ARO/AIO-94 Trial · Emmanouil Fokas · 2014 · 464 citations · Cited by this paper
  14. Changing the History of Science—An Editorial Perspective on Critical Developments in Current Citation Practice, “Forgetting” the Pioneers of Scientific Discoveries · 2026 · Related
  15. Long-Term Results of Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy: The Randomized Phase II OPRA Trial · Floris S. Verheij · 2023 · 382 citations · Cited by this paper
  16. Targeted Therapy and Oral Chemotherapy as Maintenance Treatment in Pediatric Very‐High‐Risk and High‐Risk Rhabdomyosarcoma: A Retrospective Study of Efficacy and Safety · 2026 · Related
  17. NCCN Guidelines® Insights: Rectal Cancer, Version 3.2024 · Al B. Benson · 2024 · 273 citations · Cited by this paper
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  20. Future Trends in Cancer Prevention and Interception in Cancer Predisposition Syndromes: Leveraging Insights From High‐Risk Populations · 2026 · Related
  21. Oncological outcome after MRI-based selection for neoadjuvant chemoradiotherapy in the OCUM Rectal Cancer Trial · the OCUM group · 2018 · 111 citations · Cited by this paper
  22. Neoadjuvant Chemotherapy With CAPOX Versus Chemoradiation for Locally Advanced Rectal Cancer With Uninvolved Mesorectal Fascia (CONVERT): Initial Results of a Phase III Trial · Wei-Jian Mei · 2022 · 87 citations · Cited by this paper
  23. Risk-Adapted Neoadjuvant Chemoradiotherapy in Rectal Cancer: Final Report of the OCUM Study · Reinhard Ruppert · 2023 · 84 citations · Cited by this paper
  24. The Chinese Society of Clinical Oncology (CSCO): Clinical guidelines for the diagnosis and treatment of colorectal cancer, 2024 update · Feng Wang · 2024 · 79 citations · Cited by this paper
  25. Neoadjuvant Radiotherapy Versus Surgery Alone for Stage II/III Mid-low Rectal Cancer With or Without High-risk Factors · Xiangbing Deng · 2019 · 58 citations · Cited by this paper
  26. Chemoradiotherapy and Local Excision vs Total Mesorectal Excision in T2-T3ab, N0, M0 Rectal Cancer · Xavier Serra‐Aracil · 2025 · 29 citations · Cited by this paper
  27. Early response to upfront neoadjuvant chemotherapy (CAPOX) alone in low- and intermediate-risk rectal cancer: a single-arm phase II trial · Xiangbing Deng · 2021 · 27 citations · Cited by this paper
  28. MRI‐defined T3, clear mesorectal fascia mid–low rectal cancer: is neoadjuvant treatment necessary? · Ziwei Zeng · 2024 · 9 citations · Cited by this paper
  29. A Significant Proportion of Stage II and III Rectal Cancers, Selected by Precision Magnetic Resonance, Can Safely Be Managed by Upfront Total Mesorectal Excision Surgery Without Neoadjuvant Therapy · Laura Melina Fernandez · 2025 · 5 citations · Cited by this paper
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