Research map: Multifeature sequencing-based liquid biopsy for cancer diagnosis and monitoring

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Papers in this map

  1. Improved metagenomic analysis with Kraken 2 · Derrick E. Wood · 2019 · 7612 citations · Cited by this paper
  2. Consolidated Evidence and New Frontiers of Liquid Biopsy in Lung Cancer: A Narrative Review · Ornella Cantale · 2026 · Cites this paper
  3. Genomic alterations and transcriptional phenotypes in circulating free DNA and matched metastatic tumor · Nobuyuki Takahashi · 2025 · 11 citations · Related
  4. Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies · Chetan Bettegowda · 2014 · 5213 citations · Cited by this paper
  5. Transcriptome signatures for the identification of bevacizumab responders in ovarian cancer · 2026 · Related
  6. Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients · Vancheswaran Gopalakrishnan · 2017 · 4864 citations · Cited by this paper
  7. Circulating tumor DNA precision oncology enables effective and sensitive molecular diagnostics and actionable target detection in pediatric solid tumors - the INFORM experience · 2026 · Related
  8. Genome-wide cell-free DNA fragmentation in patients with cancer · Stephen Cristiano · 2019 · 1563 citations · Cited by this paper
  9. Integrative stratification of response to immunotherapy using host and microbial signatures in patients with advanced non-small cell lung cancer · 2026 · Related
  10. Multimodal biomedical AI · Julián Acosta · 2022 · 1325 citations · Cited by this paper
  11. Cell type-specific contextualisation of the human phenome: towards the systematic treatment of all rare diseases · 2026 · Related
  12. Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set · Eric A. Klein · 2021 · 1031 citations · Cited by this paper
  13. Preservation and clonal behavior of extrachromosomal DNA in patient-derived xenograft models of childhood cancers · 2026 · Related
  14. Liquid Biopsy: From Discovery to Clinical Application · Catherine Alix-Panabières · 2021 · 1004 citations · Cited by this paper
  15. Long-read transcriptome sequencing and Drosophila-based functional validation reveal novel gene fusions in fusion panel-negative gliomas · 2026 · Related
  16. Circulating tumour cells in cancer patients: challenges and perspectives · Klaus Pantel · 2010 · 823 citations · Cited by this paper
  17. Comprehensive genomic characterization of extraintestinal pathogenic Escherichia coli isolated from neonates: multiple center insights into virulence, resistance, and transmission dynamics · 2026 · Related
  18. Metagenome analysis using the Kraken software suite · Jennifer Lu · 2022 · 808 citations · Cited by this paper
  19. Cell-Free DNA: Features and Attributes Shaping the Next Frontier in Liquid Biopsy · 2025 · Related
  20. Integrating genomic features for non-invasive early lung cancer detection · Jacob J. Chabon · 2020 · 711 citations · Cited by this paper
  21. A pan-cancer compendium of 1,294 plasma cell-free DNA methylomes and fragmentomes enabling multicancer detection · 2026 · Related
  22. Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention · Anne Marie Lennon · 2020 · 680 citations · Cited by this paper
  23. Enzymatic methyl sequencing detects DNA methylation at single-base resolution from picograms of DNA · Romualdas Vaisvila · 2021 · 583 citations · Cited by this paper
  24. Detection and characterization of lung cancer using cell-free DNA fragmentomes · Dimitrios Mathios · 2021 · 495 citations · Cited by this paper
  25. Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing · K.C. Allen Chan · 2013 · 473 citations · Cited by this paper
  26. Blood-based tests for multicancer early detection (PATHFINDER): a prospective cohort study · Deborah Schrag · 2023 · 398 citations · Cited by this paper
  27. A one-pot isothermal Cas12-based assay for the sensitive detection of microRNAs · He Yan · 2023 · 368 citations · Cited by this paper
  28. Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction · Joeri Tulkens · 2018 · 343 citations · Cited by this paper
  29. Evaluation of cell-free DNA approaches for multi-cancer early detection · Arash Jamshidi · 2022 · 336 citations · Cited by this paper
  30. Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients · Yongliang Zhang · 2021 · 303 citations · Cited by this paper
  31. Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection · Peter Ulz · 2019 · 289 citations · Cited by this paper
  32. Circulating tumor nucleic acids: biology, release mechanisms, and clinical relevance · Pavel Stejskal · 2023 · 282 citations · Cited by this paper
  33. Microfluidic space coding for multiplexed nucleic acid detection via CRISPR-Cas12a and recombinase polymerase amplification · Zhichen Xu · 2022 · 274 citations · Cited by this paper
  34. Proteomics technologies for cancer liquid biopsies · Zhiyong Ding · 2022 · 255 citations · Cited by this paper
  35. Analyzing bacterial extracellular vesicles in human body fluids by orthogonal biophysical separation and biochemical characterization · Joeri Tulkens · 2019 · 251 citations · Cited by this paper
  36. Major data analysis errors invalidate cancer microbiome findings · Abraham Gihawi · 2023 · 227 citations · Cited by this paper
  37. Machine learning enables detection of early-stage colorectal cancer by whole-genome sequencing of plasma cell-free DNA · Nathan Wan · 2019 · 211 citations · Cited by this paper
  38. A mathematical model of ctDNA shedding predicts tumor detection size · Stefano Avanzini · 2020 · 211 citations · Cited by this paper
  39. Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden · Peter Peneder · 2021 · 210 citations · Cited by this paper

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