Research map: Targeting the CTBP1–CETP axis overcomes ferroptosis resistance in non‐small cell lung cancer by altering lipid accumulation
Back to the article
Papers in this map
Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
· Freddie Bray · 2024 · 26051 citations · Cited by this paper
Engineered exosomes improve myocardial cell membrane integrity and heart function in dystrophic cardiomyopathy
· 2026 · Related
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
· Brent R. Stockwell · 2022 · 3144 citations · Cited by this paper
Remodelling the tumour microenvironment and beyond: ERO1A as a multifaceted regulator and emerging therapeutic target in cancer
· 2026 · Related
Lung Cancer
· Roy S. Herbst · 2008 · 2416 citations · Cited by this paper
Role of LncSNHG5 in MAFLD: Mechanisms of Arid1a K391 lactylation and lipid accumulation
· 2026 · Related
Non-small-cell lung cancers: a heterogeneous set of diseases
· Zhao Chen · 2014 · 2070 citations · Cited by this paper
Sintilimab plus cisplatin and nab‐paclitaxel induction treatment for locally advanced borderline‐resectable oesophageal squamous cell carcinoma: A single‐arm, prospective, phase 2 study (NEOCRTEC2001)
· 2026 · Related
Lipid metabolism in cancer: New perspectives and emerging mechanisms
· Lindsay A. Broadfield · 2021 · 828 citations · Cited by this paper
Integrating pathological morphologies and molecular profiles for clinical biomarker discovery with unified multimodal embedding
· 2026 · Related
The interaction between ferroptosis and inflammatory signaling pathways
· Yue Chen · 2023 · 564 citations · Cited by this paper
Artificial intelligence and oral microbiome: Reshaping the diagnostic and therapeutic paradigm of OSCC
· 2026 · Related
Lipid metabolic reprogramming in tumor microenvironment: from mechanisms to therapeutics
· Hao-Ran Jin · 2023 · 474 citations · Cited by this paper
Investigations into the aetiopathogenesis of orofacial granulomatosis using multiple omics technologies reveal a potential role for B cells
· 2026 · Related
Phospholipids with two polyunsaturated fatty acyl tails promote ferroptosis
· Baiyu Qiu · 2024 · 400 citations · Cited by this paper
Releasing the neuronal brake: Inhibiting AhR to enhance axon regeneration
· 2026 · Related
The International Association for the Study of Lung Cancer Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groups in the Forthcoming (Ninth) Edition of the TNM Classification for Lung Cancer
· Ramón Rami–Porta · 2024 · 372 citations · Cited by this paper
The emerging dialogue between synthetic genomics and clinical research
· 2026 · Related
Targeting protein modifications in metabolic diseases: molecular mechanisms and targeted therapies
· Xiumei Wu · 2023 · 273 citations · Cited by this paper
Ubc9‐mediated SUMOylation of Ninj1 alleviates inflammatory responses in hepatic ischaemia/reperfusion injury
· 2026 · Related
The ferroptosis inducing compounds RSL3 and ML162 are not direct inhibitors of GPX4 but of TXNRD1
· Dorian M. Cheff · 2023 · 266 citations · Cited by this paper
Endothelial Foxp1 Suppresses Atherosclerosis via Modulation of Nlrp3 Inflammasome Activation
· Tao Zhuang · 2019 · 190 citations · Cited by this paper
Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease
· Amand Floriaan Schmidt · 2021 · 149 citations · Cited by this paper
Safety and Efficacy of Obicetrapib in Patients at High Cardiovascular Risk
· Stephen James Nicholls · 2025 · 100 citations · Cited by this paper
FBXO32 promotes microenvironment underlying epithelial-mesenchymal transition via CtBP1 during tumour metastasis and brain development
· Sanjeeb Kumar Sahu · 2017 · 70 citations · Cited by this paper
CtBP2 Promotes Human Cancer Cell Migration by Transcriptional Activation of Tiam1
· S. Paliwal · 2012 · 66 citations · Cited by this paper
Estimate of Lung Cancer Mortality From Low-Dose Spiral Computed Tomography Screening Trials: Implications for Current Mass Screening Recommendations
· Edward F. Patz · 2004 · 65 citations · Cited by this paper
Tumour cells are sensitised to ferroptosis via RB1CC1‐mediated transcriptional reprogramming
· Xiangfei Xue · 2022 · 61 citations · Cited by this paper
p53 is regulated by aerobic glycolysis in cancer cells by the CtBP family of NADH-dependent transcriptional regulators
· Charles N. Birts · 2020 · 57 citations · Cited by this paper
Involvement of CtBP1 in the transcriptional activation of the MDR1 gene in human multidrug resistant cancer cells
· Wei Jin · 2007 · 56 citations · Cited by this paper
Oxidized Cholesteryl Linoleates Stimulate Endothelial Cells to Bind Monocytes via the Extracellular Signal–Regulated Kinase 1/2 Pathway
· Joakim Huber · 2002 · 51 citations · Cited by this paper
Redox-dependent Brca1 transcriptional regulation by an NADH-sensor CtBP1
· Yu Deng · 2010 · 49 citations · Cited by this paper
Inactivation of p38 MAPK contributes to stem cell-like properties of non-small cell lung cancer
· Yan Fang · 2017 · 47 citations · Cited by this paper
Theoretical framework and emerging challenges of lipid metabolism in cancer
· Qiuying Gu · 2024 · 41 citations · Cited by this paper
Activation of SAPK/JNK mediated the inhibition and reciprocal interaction of DNA methyltransferase 1 and EZH2 by ursolic acid in human lung cancer cells
· Jingjing Wu · 2015 · 39 citations · Cited by this paper
CtBP1 transactivates RAD51 and confers cisplatin resistance to breast cancer cells
· Yu Deng · 2020 · 33 citations · Cited by this paper
Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells
· Xiaoman Chen · 2018 · 31 citations · Cited by this paper
Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion
· Emma Guilbaud · 2023 · 31 citations · Cited by this paper
Pathways and Molecular Mechanisms Governing LDL Receptor Regulation
· Heidi M. Schmidt · 2025 · 29 citations · Cited by this paper
Source: OpenAlex (CC0)