Research map: Reassessment of Hematopoietic Stem Cell Aging through Metabolic Uncoupling and Mitochondrial Resilience

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  1. The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression · Jean‐Philippe Coppé · 2010 · 5342 citations · Cited by this paper
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  19. Age-dependent modulation of vascular niches for haematopoietic stem cells · Anjali P. Kusumbe · 2016 · 476 citations · Cited by this paper
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  22. Reactive Oxygen Species Regulate Hematopoietic Stem Cell Self-Renewal, Migration and Development, As Well As Their Bone Marrow Microenvironment · Aya Ludin · 2014 · 340 citations · Cited by this paper
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  24. Hematopoietic Stem Cells Count and Remember Self-Renewal Divisions · Jeffrey M. Bernitz · 2016 · 298 citations · Cited by this paper
  25. Hematopoietic Stem Cell Metabolism during Development and Aging · Ayako Nakamura‐Ishizu · 2020 · 262 citations · Cited by this paper
  26. Live-animal imaging of native haematopoietic stem and progenitor cells · Constantina Christodoulou · 2020 · 259 citations · Cited by this paper
  27. Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential · Larry L. Luchsinger · 2016 · 249 citations · Cited by this paper
  28. Dye-Independent Methods Reveal Elevated Mitochondrial Mass in Hematopoietic Stem Cells · Mariana Justino de Almeida · 2017 · 219 citations · Cited by this paper
  29. Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment · Ryō Yamamoto · 2018 · 215 citations · Cited by this paper
  30. Mitochondrial Potentiation Ameliorates Age-Related Heterogeneity in Hematopoietic Stem Cell Function · Els Mansell · 2020 · 188 citations · Cited by this paper
  31. Glycolysis: A multifaceted metabolic pathway and signaling hub · Sarah J. Kierans · 2024 · 173 citations · Cited by this paper
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  33. Decline in biological resilience as key manifestation of aging: Potential mechanisms and role in health and longevity · Svetlana V. Ukraintseva · 2020 · 100 citations · Cited by this paper
  34. Mechanisms of hematopoietic stem cell aging · Aysegul V. Ergen · 2009 · 90 citations · Cited by this paper
  35. FoxO3a regulates hematopoietic homeostasis through a negative feedback pathway in conditions of stress or aging · Kana Miyamoto · 2008 · 82 citations · Cited by this paper
  36. Differential redox-regulation and mitochondrial dynamics in normal and leukemic hematopoietic stem cells: A potential window for leukemia therapy · Katharina Mattes · 2019 · 63 citations · Cited by this paper
  37. Aging of the Hematopoietic Stem Cell Niche: New Tools to Answer an Old Question · Francesca Matteini · 2021 · 60 citations · Cited by this paper
  38. Aging is associated with functional and molecular changes in distinct hematopoietic stem cell subsets · Tsu-Yi Su · 2024 · 60 citations · Cited by this paper
  39. Autophagy counters inflammation-driven glycolytic impairment in aging hematopoietic stem cells · Paul V. Dellorusso · 2024 · 59 citations · Cited by this paper

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