Research map: Colorectal cancer organoid co-culture systems and their applications in drug screening

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  1. The biology , function , and biomedical applications of exosomes · Raghu K. Kalluri · 2020 · 10967 citations · Cited by this paper
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  15. Patient-derived organoids model treatment response of metastatic gastrointestinal cancers · Georgios Vlachogiannis · 2018 · 2177 citations · Cited by this paper
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  17. Molecular Basis of Colorectal Cancer · Sanford D. Markowitz · 2009 · 2014 citations · Cited by this paper
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  24. Organoid Modeling of the Tumor Immune Microenvironment · James T. Neal · 2018 · 1579 citations · Cited by this paper
  25. Matrigel: A complex protein mixture required for optimal growth of cell culture · Chris S. Hughes · 2010 · 1566 citations · Cited by this paper
  26. Designer matrices for intestinal stem cell and organoid culture · Nikolce Gjorevski · 2016 · 1462 citations · Cited by this paper
  27. Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids · Krijn K. Dijkstra · 2018 · 1133 citations · Cited by this paper
  28. Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis · Zhicheng Zeng · 2018 · 1096 citations · Cited by this paper
  29. Non-coding RNAs: Classification, Biology and Functioning · Sonja Hombach · 2016 · 965 citations · Cited by this paper
  30. Wnt signaling in colorectal cancer: pathogenic role and therapeutic target · Hui Zhao · 2022 · 875 citations · Cited by this paper
  31. Organoids-on-a-chip · Sunghee Estelle Park · 2019 · 847 citations · Cited by this paper
  32. Homeostatic mini-intestines through scaffold-guided organoid morphogenesis · Mikhail Yu. Nikolaev · 2020 · 770 citations · Cited by this paper
  33. Isolation and in vitro expansion of human colonic stem cells · Peter Jung · 2011 · 722 citations · Cited by this paper
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  36. Human Intestinal Organoids Maintain Self-Renewal Capacity and Cellular Diversity in Niche-Inspired Culture Condition · Masayuki Fujii · 2018 · 585 citations · Cited by this paper
  37. Signaling pathways involved in colorectal cancer: pathogenesis and targeted therapy · Qing Li · 2024 · 529 citations · Cited by this paper
  38. Bruton’s tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain · Abdalla J. Mohamed · 2009 · 520 citations · Cited by this paper
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