Research map: VBIT-4 attenuates diabetes-associated cardiovascular mitochondrial dysfunction and ROS production in a mouse model of diabetes and hyperlipidemic cellular assays

Papers in this map

1. AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading · Oleg Trott · 2009 · 38809 citations · Cited by this paper
2. Nicotine drives lung cancer progression by suppressing cuproptosis through the LIAS–DLAT axis and promoting M2 macrophage polarization · 2026 · Related
3. PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data · Daniel R. Roe · 2013 · 7855 citations · Cited by this paper
4. Cyclophilin D (CypD) promotes mitochondrial impairment, synaptic defects, cognitive loss, and tau pathology during aging · 2026 · Related
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6. Myeloid HIF-1α couples glycolytic energy supply with NCF2-dependent oxidative killing to protect against Klebsiella pneumoniae pneumonia · 2026 · Related
7. The ORCA quantum chemistry program package · Frank Neese · 2020 · 5368 citations · Cited by this paper
8. Inhibiting VDAC1 oligomerization attenuated cerebral ischemia-reperfusion injury by promoting mitophagy via reduced LONP1 interaction · 2026 · Related
9. 2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2022 · 2021 · 4808 citations · Cited by this paper
10. Crosstalk Between Mitophagy and Metabolism in Cancer: Mechanisms and Therapeutic Opportunities · 2026 · Related
11. Easy quantitative assessment of genome editing by sequence trace decomposition · Eva Karina Brinkman · 2014 · 2654 citations · Cited by this paper
12. Salvianolic acid B mitigates neuronal ferroptosis after intracerebral hemorrhage in rats through a Piezo1-associated AMPK–mTOR pathway · 2026 · Related
13. Mitochondrial function as a therapeutic target in heart failure · David Alexander Brown · 2016 · 821 citations · Cited by this paper
14. Sucralose promotes cardiac redox-metabolic remodeling through MRPL12-associated mitoribosomal stress · 2026 · Related
15. Diabetic Cardiomyopathy · WOLFGANG H. DILLMANN · 2019 · 696 citations · Cited by this paper
16. GPX3 downregulation in alveolar macrophages amplifies IL-17–dependent redox–inflammation crosstalk in ARDS · 2026 · Related
17. Transient Mammalian Cell Transfection with Polyethylenimine (PEI) · Patti A. Longo · 2013 · 648 citations · Cited by this paper
18. Loss of microglial ATM drives synaptic pruning and cognitive impairment in epilepsy · 2026 · Related
19. COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites · Thomas James Cradick · 2014 · 438 citations · Cited by this paper
20. A critical role for mitochondrial dynamics in cigarette smoke condensate-induced RPE senescence · 2026 · Related
21. Lessons learned from comparing molecular dynamics engines on the SAMPL5 dataset · Michael R. Shirts · 2016 · 410 citations · Cited by this paper
22. Therapeutic inhibition of mitochondrial reactive oxygen species with mito-TEMPO reduces diabetic cardiomyopathy · Rui Ni · 2015 · 296 citations · Cited by this paper
23. PACKMOL-Memgen: A Simple-To-Use, Generalized Workflow for Membrane-Protein–Lipid-Bilayer System Building · Stephan N Schott-Verdugo · 2019 · 272 citations · Cited by this paper
24. Mitochondrial ROS Formation in the Pathogenesis of Diabetic Cardiomyopathy · Nina Kaludercic · 2020 · 264 citations · Cited by this paper
25. VDAC1 at the Intersection of Cell Metabolism, Apoptosis, and Diseases · Varda Shoshan‐Barmatz · 2020 · 234 citations · Cited by this paper
26. Molecular complexities underlying the vascular complications of diabetes mellitus – A comprehensive review · Shalini Paul · 2020 · 205 citations · Cited by this paper
27. Development of a Nongenetic Mouse Model of Type 2 Diabetes · Elizabeth Ruth Gilbert · 2011 · 177 citations · Cited by this paper
28. Preserving Insulin Secretion in Diabetes by Inhibiting VDAC1 Overexpression and Surface Translocation in β Cells · Enming Zhang · 2018 · 175 citations · Cited by this paper
29. Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction · Danya Ben-Hail · 2016 · 156 citations · Cited by this paper
30. Diabetes Mellitus, Mitochondrial Dysfunction and Ca2+-Dependent Permeability Transition Pore · Konstantin N. Belosludtsev · 2020 · 120 citations · Cited by this paper
31. α-Ketoglutarate prevents hyperlipidemia-induced fatty liver mitochondrial dysfunction and oxidative stress by activating the AMPK-pgc-1α/Nrf2 pathway · Danyu Cheng · 2024 · 118 citations · Cited by this paper
32. A Calcium Guard in the Outer Membrane: Is VDAC a Regulated Gatekeeper of Mitochondrial Calcium Uptake? · Paulina Sander · 2021 · 79 citations · Cited by this paper
33. Closure of VDAC causes oxidative stress and accelerates the Ca2+-induced mitochondrial permeability transition in rat liver mitochondria · Andrey P. Tikunov · 2010 · 74 citations · Cited by this paper
34. Diabetes-Related Heart Failure · Yoshiyuki Bando · 2014 · 72 citations · Cited by this paper
35. VDAC: old protein with new roles in diabetes · Koh Sasaki · 2012 · 62 citations · Cited by this paper
36. The Etiology and Pathogenesis of Non-insulin-dependent Diabetes · Leif Groop · 1992 · 37 citations · Cited by this paper
37. Effect of Chronic Treatment with Uridine on Cardiac Mitochondrial Dysfunction in the C57BL/6 Mouse Model of High-Fat Diet–Streptozotocin-Induced Diabetes · Natalia V. Belosludtseva · 2022 · 32 citations · Cited by this paper
38. VDAC1 Knockout Affects Mitochondrial Oxygen Consumption Triggering a Rearrangement of ETC by Impacting on Complex I Activity · Andrea Magrì · 2023 · 31 citations · Cited by this paper
39. Pore-Forming VDAC Proteins of the Outer Mitochondrial Membrane: Regulation and Pathophysiological Role · Natalia V. Belosludtseva · 2024 · 20 citations · Cited by this paper

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