Research map: BPAF-induced inflammatory response via estrogen signaling: insights from in vivo and in vitro evidence

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  1. Occurrence, toxicity and ecological risk of Bisphenol A analogues in aquatic environment – A review · Jianchao Liu · 2020 · 448 citations · Cited by this paper
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  3. Role of Estrogen Receptors and G Protein-Coupled Estrogen Receptor in Regulation of Hypothalamus–Pituitary–Testis Axis and Spermatogenesis · Adele Chimento · 2014 · 268 citations · Cited by this paper
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  5. Estrogen Receptor Signaling in the Immune System · Binita Chakraborty · 2022 · 268 citations · Cited by this paper
  6. Alternariol, a mycotoxin, induces oxidative stress, inflammation, and apoptosis in human astrocytes: Protective effects of eicosapentaenoic acid · 2026 · Related
  7. Immunomodulatory effects of synthetic endocrine disrupting chemicals on the development and functions of human immune cells · Karolina Nowak · 2019 · 242 citations · Cited by this paper
  8. Integrative network toxicology identifies SLC5A2 as a key mediator of tetrasodium pyrophosphate-induced renal fibrosis · 2026 · Related
  9. Bisphenol A Impairs Mitochondrial Function in the Liver at Doses below the No Observed Adverse Effect Level · Min Kyong Moon · 2012 · 231 citations · Cited by this paper
  10. RIFM fragrance ingredient safety assessment, 3,5,5-trimethylcyclohexanol, CAS Registry Number 116-02-9 · 2026 · Related
  11. Occurrence and Partitioning of Bisphenol Analogues in Adults’ Blood from China · Hangbiao Jin · 2017 · 200 citations · Cited by this paper
  12. Update to RIFM fragrance ingredient safety assessment, 2-propanol, 1,1′,1′,1'-(1,2-ethanediyldinitrilo)tetrakis-, CAS Registry Number 102-60-3 · 2026 · Related
  13. Bisphenol AF and Bisphenol B Exert Higher Estrogenic Effects than Bisphenol A via G Protein-Coupled Estrogen Receptor Pathway · Lin-Ying Cao · 2017 · 174 citations · Cited by this paper
  14. Redox-dependent cytoprotection by zerumbone via Nrf2–Keap1 mediated restoration of antioxidant and apoptotic balance in Mancozeb-exposed cells · 2026 · Related
  15. Oxidative Stress, Endocrine Disturbance, and Immune Interference in Humans Showed Relationships to Serum Bisphenol Concentrations in a Dense Industrial Area · Chuanzi Gao · 2021 · 159 citations · Cited by this paper
  16. Microplastics and mammary carcinogenesis: A review of in vitro and in vivo experimental evidence · 2026 · Related
  17. The impact of endocrine-disrupting chemicals on oxidative stress and innate immune response in zebrafish embryos · Hai Xu · 2013 · 156 citations · Cited by this paper
  18. Insights into natural polysaccharides in alleviating drug-induced liver injury: Protective mechanisms and recent advances · 2026 · Related
  19. Bisphenol analogue concentrations in human breast milk and their associations with postnatal infant growth · Hangbiao Jin · 2019 · 149 citations · Cited by this paper
  20. G Protein-Coupled Estrogen Receptor in Immune Cells and Its Role in Immune-Related Diseases · George Notas · 2020 · 106 citations · Cited by this paper
  21. Evaluation of the in vitro estrogenicity of emerging bisphenol analogs and their respective estrogenic contributions in municipal sewage sludge in China · Ting Ruan · 2014 · 105 citations · Cited by this paper
  22. Endocrine disrupting chemicals in indoor dust: A review of temporal and spatial trends, and human exposure · Linyan Zhu · 2023 · 103 citations · Cited by this paper
  23. Differential in Vitro Biological Action, Coregulator Interactions, and Molecular Dynamic Analysis of Bisphenol A (BPA), BPAF, and BPS Ligand–ERα Complexes · Yin Li · 2018 · 101 citations · Cited by this paper
  24. p38 MAPK inhibitors attenuate pro-inflammatory cytokine production and the invasiveness of human U251 glioblastoma cells · Yiu To Yeung · 2012 · 89 citations · Cited by this paper
  25. GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response · Paola De Marco · 2016 · 80 citations · Cited by this paper
  26. Environmental contaminant BPA causes intestinal damage by disrupting cellular repair and injury homeostasis in vivo and in vitro · Kai You Wang · 2021 · 76 citations · Cited by this paper
  27. Bisphenol AF exerts estrogenic activity in MCF-7 cells through activation of Erk and PI3K/Akt signals via GPER signaling pathway · Bingli Lei · 2018 · 64 citations · Cited by this paper
  28. Occurrence of Free-Form and Conjugated Bisphenol Analogues in Marine Organisms · Nan Zhao · 2021 · 64 citations · Cited by this paper
  29. Low-dose Bisphenol-A regulates inflammatory cytokines through GPR30 in mammary adipose cells · Ilaria Cimmino · 2019 · 60 citations · Cited by this paper
  30. In vitro profiling of toxicity and endocrine disrupting effects of bisphenol analogues by employing MCF ‐7 cells and two‐hybrid yeast bioassay · Bingli Lei · 2016 · 54 citations · Cited by this paper
  31. Modulation of cytokine/chemokine production in human macrophages by bisphenol A: A comparison to analogues and interactions with genistein · Yingjia Chen · 2018 · 51 citations · Cited by this paper
  32. G Protein-Coupled Estrogen Receptor 1 Regulates Human Neutrophil Functions · M.C. Rodenas · 2017 · 50 citations · Cited by this paper
  33. Different effects of bisphenol a and its halogenated derivatives on the reproduction and development of Oryzias melastigma under environmentally relevant doses · Qiansheng Huang · 2017 · 49 citations · Cited by this paper
  34. The imbalance of Treg/Th17 cells induced by perinatal bisphenol A exposure is associated with activation of the PI3K/Akt/mTOR signaling pathway in male offspring mice · Liang Gao · 2020 · 48 citations · Cited by this paper
  35. Occurrence, placental transfer, and health risks of emerging endocrine-disrupting chemicals in pregnant women · Aijing Li · 2023 · 41 citations · Cited by this paper
  36. Comparison of the mechanisms of estrogen disrupting effects between triphenyl phosphate (TPhP) and tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) · Xiaoya Ji · 2021 · 39 citations · Cited by this paper
  37. A critical review to identify data gaps and improve risk assessment of bisphenol A alternatives for human health · Sakina Mhaouty‐Kodja · 2024 · 37 citations · Cited by this paper
  38. Bisphenol A triggers proliferation and migration of laryngeal squamous cell carcinoma via GPER mediated upregulation of IL‐6 · Shisheng Li · 2017 · 34 citations · Cited by this paper
  39. Effects and mechanisms of endocrine disruptor bisphenol AF on male reproductive health: A mini review · Senlin Xue · 2024 · 34 citations · Cited by this paper

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