Research map: Sodium Butyrate Attenuates Renal Fibrosis by Regulating Glycolysis and Histone H4K12 Lactylation in Diabetic Kidney Disease

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  1. KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease · Paul E. Stevens · 2024 · 8239 citations · Cited by this paper
  2. Economic Impact of Multidisciplinary Pre‐operative Diabetes Care Versus Usual Care in Adults Undergoing Elective Non‐cardiac Surgery in Australia: A Trial‐Based Analysis · 2026 · Related
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  11. Lactate promotes endothelial-to-mesenchymal transition via Snail1 lactylation after myocardial infarction · Min Fan · 2023 · 405 citations · Cited by this paper
  12. Diagnostic Yield of Structured Cushing Syndrome Evaluation in Treatment‐Resistant Non‐Diabetic Obesity: A Retrospective Pilot Study · 2026 · Related
  13. Dietary Fiber Protects against Diabetic Nephropathy through Short-Chain Fatty Acid–Mediated Activation of G Protein–Coupled Receptors GPR43 and GPR109A · Yan Jun Li · 2020 · 373 citations · Cited by this paper
  14. Exercise Snacks Are Feasible to Perform in the Real World and Improve Physical Capacity for Adults Living With Non‐Insulin Treated Type 2 Diabetes: A Randomised Trial · 2026 · Related
  15. ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion · Rongxuan Zhu · 2024 · 295 citations · Cited by this paper
  16. Real‐World Effectiveness and Safety of Finerenone in People With Type 2 Diabetes and Chronic Kidney Disease: A Spanish Multicentre Retrospective Observational Study ( MEDFINE ‐ RWD ) · 2026 · Related
  17. Renal protective effects of empagliflozin via inhibition of EMT and aberrant glycolysis in proximal tubules · Jinpeng Li · 2020 · 254 citations · Cited by this paper
  18. Methodological and Conceptual Concerns Regarding the 24‐h Glycaemia/C‐Peptide Ratio as a Novel Insulin Sensitivity Index · 2026 · Related
  19. Butyrate ameliorates skeletal muscle atrophy in diabetic nephropathy by enhancing gut barrier function and FFA2‐mediated PI3K/Akt/mTOR signals · Gang Tang · 2021 · 214 citations · Cited by this paper
  20. Efficacy and Safety of Once‐Weekly Semaglutide 2.0 mg as an Add‐On to Dose‐Reduced Insulin Glargine versus Dose‐Titrated Insulin Glargine in People With Type 2 Diabetes and Overweight ( SUSTAIN OPTIMIZE ) · 2026 · Related
  21. The Role of the Gut Microbiome in Diabetes and Obesity-Related Kidney Disease · Amgad A. Zaky · 2021 · 177 citations · Cited by this paper
  22. Changing epidemiology of chronic kidney disease as a result of type 2 diabetes mellitus from 1990 to 2017: Estimates from Global Burden of Disease 2017 · Huixian Li · 2020 · 160 citations · Cited by this paper
  23. Lactate drives epithelial-mesenchymal transition in diabetic kidney disease via the H3K14la/KLF5 pathway · Xuanxuan Zhang · 2024 · 157 citations · Cited by this paper
  24. Recent Advances in Diabetic Kidney Diseases: From Kidney Injury to Kidney Fibrosis · Peir‐Haur Hung · 2021 · 148 citations · Cited by this paper
  25. The Warburg Effect in Diabetic Kidney Disease · Guanshi Zhang · 2018 · 104 citations · Cited by this paper
  26. Oxidative stress and inflammation are mediated via aryl hydrocarbon receptor signalling in idiopathic membranous nephropathy · Yanni Wang · 2023 · 87 citations · Cited by this paper
  27. Comprehensive review of histone lactylation: Structure, function, and therapeutic targets · Kaiwen Xu · 2024 · 86 citations · Cited by this paper
  28. Abnormal lactate metabolism is linked to albuminuria and kidney injury in diabetic nephropathy · Kengo Azushima · 2023 · 81 citations · Cited by this paper
  29. Localization of members of MCT monocarboxylate transporter family Slc16 in the kidney and regulation during metabolic acidosis · Helen M. Becker · 2010 · 68 citations · Cited by this paper
  30. Associations of Plasma Biomarkers of Inflammation, Fibrosis, and Kidney Tubular Injury With Progression of Diabetic Kidney Disease: A Cohort Study · Orlando M. Gutiérrez · 2021 · 67 citations · Cited by this paper
  31. Lactylation in health and disease: physiological or pathological? · Lijun Zhao · 2025 · 66 citations · Cited by this paper
  32. Sodium butyrate inhibits aerobic glycolysis of hepatocellular carcinoma cells via the c‐myc/hexokinase 2 pathway · Qiang Yu · 2022 · 57 citations · Cited by this paper
  33. Non-invasive metabolic biomarkers for early diagnosis of diabetic nephropathy: Meta-analysis of profiling metabolomics studies · Amir Roointan · 2021 · 55 citations · Cited by this paper
  34. A systematic review and meta-analysis of gut microbiota in diabetic kidney disease: Comparisons with diabetes mellitus, non-diabetic kidney disease, and healthy individuals · Shisheng Han · 2022 · 54 citations · Cited by this paper
  35. Butyrate alleviates diabetic kidney disease by mediating the miR‐7a‐5p/P311/TGF‐β1 pathway · Yi Chun Du · 2020 · 53 citations · Cited by this paper
  36. Sodium Butyrate Attenuates Diabetic Kidney Disease Partially via Histone Butyrylation Modification · Tingting Zhou · 2022 · 52 citations · Cited by this paper
  37. Fatty Acid β-Oxidation in Kidney Diseases: Perspectives on Pathophysiological Mechanisms and Therapeutic Opportunities · Zhumei Gao · 2022 · 51 citations · Cited by this paper
  38. Glycolytic lactate in diabetic kidney disease · Manjula Darshi · 2024 · 51 citations · Cited by this paper
  39. Epigenetic alterations and memory: key players in the development/progression of chronic kidney disease promoted by acute kidney injury and diabetes · Imari Mimura · 2024 · 49 citations · Cited by this paper

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