Research map: Effects of CYP3A4, CYP3A5, and ABCB1 genetic variants on tacrolimus metabolism during the early period after kidney transplantation

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  1. A "Silent" Polymorphism in the MDR 1 Gene Changes Substrate Specificity · Chava Kimchi‐Sarfaty · 2006 · 2489 citations · Cited by this paper
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  15. The Influence of Pharmacogenetics on the Time to Achieve Target Tacrolimus Concentrations after Kidney Transplantation · Iain A. M. MacPhee · 2004 · 258 citations · Cited by this paper
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  17. The Role of Pharmacogenetics in the Disposition of and Response to Tacrolimus in Solid Organ Transplantation · Dennis Alexander Hesselink · 2013 · 236 citations · Cited by this paper
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  19. Epidemiology of end-stage kidney disease · Ryan Gupta · 2021 · 190 citations · Cited by this paper
  20. Both donor and recipient CYP3A5 gene polymorphisms represent as significant factors influencing Tacrolimus weight-dose adjusted concentration in the early phase after living donor liver transplantation · 2024 · Related
  21. Immunosuppression trends in solid organ transplantation: The future of individualization, monitoring, and management · Nicole Ann Pilch · 2020 · 186 citations · Cited by this paper
  22. Low tacrolimus concentrations and increased risk of early acute rejection in adult renal transplantation · Christine E. Staatz · 2001 · 162 citations · Cited by this paper
  23. Pharmacokinetic considerations related to therapeutic drug monitoring of tacrolimus in kidney transplant patients · Louise M. Andrews · 2017 · 143 citations · Cited by this paper
  24. Tacrolimus - Pharmacokinetic Considerations for Clinicians · Katharina Schütte‐Nütgen · 2018 · 99 citations · Cited by this paper
  25. Impact of the CYP3A5, CYP3A4, COMT, IL-10 and POR Genetic Polymorphisms on Tacrolimus Metabolism in Chinese Renal Transplant Recipients · Chuanjiang Li · 2014 · 80 citations · Cited by this paper
  26. CYP3A7, CYP3A5, CYP3A4, and ABCB1 Genetic Polymorphisms, Cyclosporine Concentration, and Dose Requirement in Transplant Recipients · Séverine Crettol · 2008 · 74 citations · Cited by this paper
  27. Fast Tac Metabolizers at Risk—It is Time for a C/D Ratio Calculation · Katharina Schütte‐Nütgen · 2019 · 72 citations · Cited by this paper
  28. CYP3A5 gene polymorphisms and their impact on dosage and trough concentration of tacrolimus among kidney transplant patients: a systematic review and meta-analysis · Abdul Rafay Khan · 2020 · 71 citations · Cited by this paper
  29. The Clinical Impact of the C0/D Ratio and the CYP3A5 Genotype on Outcome in Tacrolimus Treated Kidney Transplant Recipients · Teun van Gelder · 2020 · 71 citations · Cited by this paper
  30. Sex-Dependent Genetic Markers of CYP3A4 Expression and Activity in Human Liver Microsomes · Markus Schirmer · 2007 · 69 citations · Cited by this paper
  31. Impact of CYP3A5 and CYP3A4 gene polymorphisms on dose requirement of calcineurin inhibitors, cyclosporine and tacrolimus, in renal allograft recipients of North India · Ranjana Singh · 2009 · 55 citations · Cited by this paper
  32. Evaluation of limited sampling methods for estimation of tacrolimus exposure in adult kidney transplant recipients · Katherine A. Barraclough · 2010 · 53 citations · Cited by this paper
  33. The Effect of MDR1 (ABCB1) Polymorphism on the Pharmacokinetic of Tacrolimus in Turkish Renal Transplant Recipients · S. Halide Akbaş · 2006 · 49 citations · Cited by this paper
  34. Clinical and genetic factors affecting tacrolimus trough levels and drug-related outcomes in Korean kidney transplant recipients · In‐Wha Kim · 2011 · 47 citations · Cited by this paper
  35. Impact of CYP3A5 polymorphism on trough concentrations and outcomes of tacrolimus minimization during the early period after kidney transplantation · Khemjira Yaowakulpatana · 2015 · 36 citations · Cited by this paper
  36. Highly sensitive and rapid determination of tacrolimus in peripheral blood mononuclear cells by liquid chromatography–tandem mass spectrometry · Soma Bahmany · 2018 · 35 citations · Cited by this paper
  37. Higher tacrolimus trough levels on days 2–5 post‐renal transplant are associated with reduced rates of acute rejection · Conall M. O’Seaghdha · 2009 · 32 citations · Cited by this paper
  38. CYP 3A pharmacogenetics and tacrolimus disposition in adult heart transplant recipients · Kimberly M. Deininger · 2016 · 31 citations · Cited by this paper
  39. Association of CYP3A4/5, ABCB1 and ABCC2 polymorphisms and clinical outcomes of Thai breast cancer patients treated with tamoxifen · Insee Sensorn · 2013 · 30 citations · Cited by this paper

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