Research map: COMBINED SECOND HARMONIC AND LINEAR LIGHT SCATTERING AS A TOOL FOR SOLUBILITY AND AGGREGATION SCREENING
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Strategies to Address Low Drug Solubility in Discovery and Development
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· Anura S. Indulkar · 2019 · 203 citations · Cited by this paper
Exploiting the Phenomenon of Liquid–Liquid Phase Separation for Enhanced and Sustained Membrane Transport of a Poorly Water-Soluble Drug
· Anura S. Indulkar · 2016 · 195 citations · Cited by this paper
Biological assay challenges from compound solubility: strategies for bioassay optimization
· Li Di · 2006 · 181 citations · Cited by this paper
Development of a high throughput equilibrium solubility assay using miniaturized shake‐flask method in early drug discovery
· Liping Zhou · 2007 · 153 citations · Cited by this paper
Thermodynamics and Kinetics of Prenucleation Clusters, Classical and Non‐Classical Nucleation
· Dirk Zahn · 2015 · 128 citations · Cited by this paper
Glass-forming ability of compounds in marketed amorphous drug products
· Nicole Wyttenbach · 2016 · 108 citations · Cited by this paper
Optimizing solubility: Kinetic versus thermodynamic solubility temptations and risks
· Christoph Saal · 2012 · 102 citations · Cited by this paper
Flow Induced Dispersion Analysis Quantifies Noncovalent Interactions in Nanoliter Samples
· Henrik M. Jensen · 2010 · 95 citations · Cited by this paper
Comparison of Nephelometric, UV-Spectroscopic, and HPLC Methods for High-Throughput Determination of Aqueous Drug Solubility in Microtiter Plates
· Bettina Hoelke · 2009 · 87 citations · Cited by this paper
Thermodynamics of Highly Supersaturated Aqueous Solutions of Poorly Water-Soluble Drugs—Impact of a Second Drug on the Solution Phase Behavior and Implications for Combination Products
· Niraj S. Trasi · 2015 · 86 citations · Cited by this paper
Capillary flow experiments for thermodynamic and kinetic characterization of protein liquid-liquid phase separation
· Emil G. P. Stender · 2021 · 80 citations · Cited by this paper
Kinetic Pathways and Mechanisms of Two-Step Nucleation in Crystallization
· Can Guo · 2016 · 74 citations · Cited by this paper
High throughput solubility measurement with automated polarized light microscopy analysis
· Kiyohiko Sugano · 2006 · 68 citations · Cited by this paper
Supersaturation and crystallization: non-equilibrium dynamics of amorphous solid dispersions for oral drug delivery
· Kohsaku Kawakami · 2016 · 61 citations · Cited by this paper
Insights into Nano- and Micron-Scale Phase Separation in Amorphous Solid Dispersions Using Fluorescence-Based Techniques in Combination with Solid State Nuclear Magnetic Resonance Spectroscopy
· Hitesh S. Purohit · 2017 · 58 citations · Cited by this paper
Nonlinear Optical Imaging for Sensitive Detection of Crystals in Bulk Amorphous Powders
· Umesh S. Kestur · 2012 · 49 citations · Cited by this paper
Using Environment-Sensitive Fluorescent Probes to Characterize Liquid-Liquid Phase Separation in Supersaturated Solutions of Poorly Water Soluble Compounds
· Shweta A. Raina · 2015 · 47 citations · Cited by this paper
Revisiting independent versus dependent scattering regimes in suspensions or aggregates of spherical particles
· Tiphaine Galy · 2020 · 47 citations · Cited by this paper
Theoretical Considerations of the Prigogine–Defay Ratio with Regard to the Glass-Forming Ability of Drugs from Undercooled Melts
· Nicole Wyttenbach · 2015 · 43 citations · Cited by this paper
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