Research map: Mendelian randomization applied to cancer: What it has and has not achieved

Back to the article

Papers in this map

  1. Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression · Jack Bowden · 2015 · 10872 citations · Cited by this paper
  2. The association of urinary levels of heavy metals with childhood acute leukemia and its socio-environmental risk factors: A case-control study · 2026 · Related
  3. Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator · Jack Bowden · 2016 · 9860 citations · Cited by this paper
  4. Geographic differences in breast cancer incidence and trends in young women ages <40 in the United States · 2026 · Related
  5. Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases · Marie Verbanck · 2018 · 9406 citations · Cited by this paper
  6. Association between cesarean delivery and pediatric leukemia: A case-control study using a Japanese administrative claims database · 2026 · Related
  7. ‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?* · George Davey Smith · 2003 · 6492 citations · Cited by this paper
  8. Beyond development: Global disparities in gastrointestinal cancer outcomes across 176 countries · 2026 · Related
  9. Strengthening the Reporting of Observational Studies in Epidemiology Using Mendelian Randomization · Veronika Whitesell Skrivankova · 2021 · 4197 citations · Cited by this paper
  10. Response to: “Accurate index event definitions are crucial in TriNetX-based cancer epidemiology studies” · 2026 · Related
  11. The Causes of Cancer: Quantitative Estimates of Avoidable Risks of Cancer in the United States Today · Richard Doll · 1981 · 3933 citations · Cited by this paper
  12. The gut microbiota and colorectal lesions subtyped in adenoma-carcinoma sequence and serrated pathway · 2026 · Related
  13. Body Fatness and Cancer — Viewpoint of the IARC Working Group · Béatrice Secretan · 2016 · 3666 citations · Cited by this paper
  14. Serum metabolites related to ultra-processed food intake in association with mortality: A prospective cohort study in the UK biobank · 2026 · Related
  15. Effects of a Combination of Beta Carotene and Vitamin A on Lung Cancer and Cardiovascular Disease · Gilbert S. Omenn · 1996 · 3664 citations · Cited by this paper
  16. Changes in childhood cancer incidence rates and trends in Canada (2001–2023): Results from the Cancer in Young People in Canada surveillance program · 2026 · Related
  17. Effect of Selenium and Vitamin E on Risk of Prostate Cancer and Other Cancers · Scott Michael Lippman · 2008 · 2133 citations · Cited by this paper
  18. The association between diabetes mellitus and the risk of anal cancer: Results from a large nationwide cohort study in Taiwan · 2026 · Related
  19. Insulin and insulin-like growth factor signalling in neoplasia · Michaël Pollak · 2008 · 2071 citations · Cited by this paper
  20. Too much of a good thing? Exercise and risk of colon cancer · 2026 · Related
  21. Strengthening the reporting of observational studies in epidemiology using mendelian randomisation (STROBE-MR): explanation and elaboration · Veronika Whitesell Skrivankova · 2021 · 1750 citations · Cited by this paper
  22. Mendelian randomization: prospects, potentials, and limitations · George Davey Smith · 2004 · 1306 citations · Cited by this paper
  23. Prospective Study of Colorectal Cancer Risk in Men and Plasma Levels of Insulin-Like Growth Factor (IGF)-I and IGF-Binding Protein-3 · J. Ma · 1999 · 1123 citations · Cited by this paper
  24. Identification of a variant associated with adult-type hypolactasia · Nabil Sabri Enattah · 2002 · 1059 citations · Cited by this paper
  25. Folic Acid for the Prevention of Colorectal Adenomas · Bernard F. Cole · 2007 · 934 citations · Cited by this paper
  26. Carcinogenicity of alcoholic beverages · Robert A. Baan · 2007 · 884 citations · Cited by this paper
  27. Low-Fat Dietary Pattern and Risk of Invasive Breast Cancer · Ross L. Prentice · 2006 · 829 citations · Cited by this paper
  28. Variation inPCSK9andHMGCRand Risk of Cardiovascular Disease and Diabetes · Brian A. Ference · 2016 · 792 citations · Cited by this paper
  29. The Impact of Residual and Unmeasured Confounding in Epidemiologic Studies: A Simulation Study · Zoe Fewell · 2007 · 784 citations · Cited by this paper
  30. Insulin-like growth factor 1 (IGF1), IGF binding protein 3 (IGFBP3), and breast cancer risk: pooled individual data analysis of 17 prospective studies · Timothy J Key · 2010 · 668 citations · Cited by this paper
  31. NAT2 slow acetylation, GSTM1 null genotype, and risk of bladder cancer: results from the Spanish Bladder Cancer Study and meta-analyses · Montserrat García‐Closas · 2005 · 629 citations · Cited by this paper
  32. Telomere Length and Risk of Incident Cancer and Cancer Mortality · Peter Willeit · 2010 · 490 citations · Cited by this paper
  33. Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses · Ben Michael Brumpton · 2020 · 432 citations · Cited by this paper
  34. Use of genetic variation to separate the effects of early and later life adiposity on disease risk: mendelian randomisation study · Tom G. Richardson · 2020 · 369 citations · Cited by this paper
  35. Constitutive telomerase expression promotes mammary carcinomas in aging mice · Steven E. Artandi · 2002 · 316 citations · Cited by this paper
  36. Alcohol, ALDH2, and Esophageal Cancer: A Meta-analysis Which Illustrates the Potentials and Limitations of a Mendelian Randomization Approach · Sarah J. Lewis · 2005 · 238 citations · Cited by this paper
  37. Dairying, diseases and the evolution of lactase persistence in Europe · Richard P. Evershed · 2022 · 229 citations · Cited by this paper
  38. Mendelian Randomization for Strengthening Causal Inference in Observational Studies · George Davey Smith · 2010 · 215 citations · Cited by this paper
  39. COLON CANCER AND BLOOD-CHOLESTEROL · Geoffrey A Rose · 1974 · 206 citations · Cited by this paper

Source: OpenAlex (CC0)