Research map: High Prevalence of Preexisting Neutralizing Antibodies Against Adeno-Associated Virus Capsids in Mongolian People with Hemophilia
Back to the article
Papers in this map
Clades of Adeno-Associated Viruses Are Widely Disseminated in Human Tissues
· Guangping Gao · 2004 · 1088 citations · Cited by this paper
Retroviral Transduction of Human CD4 + T Cells with Membrane-Attached IL-10 Generates Type 1-Like Regulatory T Cells
· 2026 · Related
AAV Vector Immunogenicity in Humans: A Long Journey to Successful Gene Transfer
· Helena Costa Verdera · 2020 · 655 citations · Cited by this paper
Optimization of Alpha-1 Antitrypsin Expression from Adeno-Associated Virus Vectors
· 2026 · Related
Gene Therapy with Etranacogene Dezaparvovec for Hemophilia B
· Steven W. Pipe · 2023 · 367 citations · Cited by this paper
Prenatal Intraportal Delivery of Polymeric Nanoparticles to Fetal Rhesus Monkeys ( Macaca mulatta )
· 2026 · Related
Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease
· Kiran Musunuru · 2025 · 357 citations · Cited by this paper
Quantification of Lentiviral Vectors with Nucleic Acid Dyes
· 2026 · Related
Haemophilia
· Erik E. Berntorp · 2021 · 332 citations · Cited by this paper
CAR-T Cell Therapy: Manufacturing Platforms and Clinical Consequences
· 2026 · Related
Two-Year Outcomes of Valoctocogene Roxaparvovec Therapy for Hemophilia A
· Johnny Ndoni Mahlangu · 2023 · 204 citations · Cited by this paper
A Review of the Challenge of Pre-Existing Humoral Immunity in Adeno-Associated Virus Gene Therapy and Potential Solutions
· 2026 · Related
Immunogenicity assessment of AAV-based gene therapies: An IQ consortium industry white paper
· Tong‐Yuan Yang · 2022 · 127 citations · Cited by this paper
Capsid Engineering of Adeno-Associated Viruses for Targeted Gene Therapy in Kidney Diseases
· 2026 · Related
Exposure to wild-type AAV drives distinct capsid immunity profiles in humans
· Klaudia Kuranda · 2018 · 108 citations · Cited by this paper
Ethical and Regulatory Considerations for Developing Gene Therapies Involving Genome Editing
· 2026 · Related
Understanding AAV vector immunogenicity: from particle to patient
· Bijay P. Dhungel · 2024 · 83 citations · Cited by this paper
Helper-Dependent Adenoviral Vectors: Recent Advances and Emerging Applications
· 2026 · Related
Global seroprevalence of neutralizing antibodies against adeno-associated virus serotypes used for human gene therapies
· Amit Chhabra · 2024 · 73 citations · Cited by this paper
Lentiviral Gene Therapy with CD34+ Hematopoietic Cells for Hemophilia A
· Alok Srivastava · 2024 · 58 citations · Cited by this paper
Gene therapy for hemophilia – From basic science to first approvals of “one-and-done” therapies
· Roland W. Herzog · 2025 · 35 citations · Cited by this paper
Preexisting antibody assays for gene therapy: Considerations on patient selection cutoffs and companion diagnostic requirements
· Manuela Braun · 2024 · 31 citations · Cited by this paper
A sensitive and reproducible cell-based assay via secNanoLuc to detect neutralizing antibody against adeno-associated virus vector capsid
· Nemekhbayar Baatartsogt · 2021 · 27 citations · Cited by this paper
The seroprevalence of neutralizing antibodies against the adeno-associated virus capsids in Japanese hemophiliacs
· Yuji Kashiwakura · 2022 · 27 citations · Cited by this paper
Multicenter assessment and longitudinal study of the prevalence of antibodies and related adaptive immune responses to AAV in adult males with hemophilia
· Ingrid Pabinger · 2024 · 26 citations · Cited by this paper
Hepatitis B, C, and D Virus Infection among Population Aged 10–64 Years in Mongolia: Baseline Survey Data of a Nationwide Cancer Cohort Study
· Davaalkham Dambadarjaa · 2022 · 21 citations · Cited by this paper
Hepatitis E Virus (HEV) Spreads from Pigs and Sheep in Mongolia
· Enkhbaatar Batmagnai · 2023 · 15 citations · Cited by this paper
Helicobacter pylori Across Continents: Contrasts in Epidemiology, Genetics, Clinical Impact, and Management Between East and West
· Ken Namikawa · 2025 · 14 citations · Cited by this paper
The WFH Guidelines for the Management of Haemophilia: AAV Gene Therapy, 2025
· Glenn F. Pierce · 2025 · 13 citations · Cited by this paper
Contemporary approaches to treat people with hemophilia: what’s new and what’s not?
· Leonard A. Valentino · 2025 · 10 citations · Cited by this paper
Global prophylaxis trends in hemophilia: a macroeconomic analysis and its association with world development indicators
· M. Joseph John · 2024 · 8 citations · Cited by this paper
Prevalence of Neutralizing Antibodies Against AAV Serotypes 2 and 9 in Healthy Participants from Multiple Centers Across China and Patients with DMD/BMD
· Xuzhen Qin · 2024 · 8 citations · Cited by this paper
The strength and weakness of Mongolian healthcare: from nomadic Gobi to Ulaanbaatar
· Wei‐Ti Chen · 2025 · 7 citations · Cited by this paper
Etranacogene dezaparvovec in people with hemophilia B with preexisting adeno-associated virus 5 neutralizing antibodies: 4-year subgroup results from the HOPE-B trial
· Robert Klamroth · 2026 · 6 citations · Cited by this paper
Etranacogene dezaparvovec in people with hemophilia B and without adeno-associated virus serotype 5 neutralizing antibodies: a 4-year subgroup analysis of the Health Outcomes with Padua Gene; Evaluation in Hemophilia B (HOPE-B) trial
· Priyanka Raheja · 2025 · 4 citations · Cited by this paper
A comprehensive care pathway of gene therapy for hemophilia based on current guideline documents and summary of product characteristics: communication from the ISTH SSC working group on gene therapy
· Caroline M. A. Mussert · 2025 · 3 citations · Cited by this paper
Total and Neutralizing Antibody Seroprevalence of Hepatotropic Adeno-Associated Virus Among Healthy and Hemophilia A or B Population from India
· Hubert Darius J. Daniel · 2025 · 2 citations · Cited by this paper
Haemophilia Gene Therapy: Patient Selection and Experience in the Era of Precision Medicine
· Dr Sara Boyce · 2024 · 1 citation · Cited by this paper
Source: OpenAlex (CC0)