Research map: tRNA-derived fragment tRF-17-8SPOL52 induces resistance to bortezomib in multiple myeloma via autophagy activation

Back to the article

Papers in this map

  1. KEGG: biological systems database as a model of the real world · Minoru I. Kanehisa · 2024 · 2543 citations · Cited by this paper
  2. Small-molecule LIFR inhibitors attenuate renal tubulointerstitial fibrosis · 2026 · Related
  3. Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles · Mark E. Davis · 2010 · 2508 citations · Cited by this paper
  4. Indole-3-carbaldehyde mitigates fibrosis progression in MASH with T2DM via the SIRT1/TGF-β/SMAD signaling pathway · 2026 · Related
  5. Cancer incidence and mortality in China, 2016 · Rongshou Zheng · 2022 · 1607 citations · Cited by this paper
  6. Microbial influence on tryptophan metabolism in tumors:Mechanisms and potential clinical applications · 2026 · Related
  7. Meta-analysis of tRNA derived RNA fragments reveals that they are evolutionarily conserved and associate with AGO proteins to recognize specific RNA targets · Pankaj Kumar · 2014 · 711 citations · Cited by this paper
  8. HACD1-driven long-chain fatty acid metabolic reprogramming enhances esophageal cancer tumorigenicity · 2026 · Related
  9. Ciltacabtagene Autoleucel, an Anti–B-cell Maturation Antigen Chimeric Antigen Receptor T-Cell Therapy, for Relapsed/Refractory Multiple Myeloma: CARTITUDE-1 2-Year Follow-Up · Thomas G. Martin · 2022 · 670 citations · Cited by this paper
  10. TNFAIP1 as a novel therapeutic target in ulcerative colitis and salidroside as its potential inhibitor · 2026 · Related
  11. Bone marrow stromal cell–derived exosomes as communicators in drug resistance in multiple myeloma cells · Jinheng Wang · 2014 · 453 citations · Cited by this paper
  12. EGR2 promotes vascular smooth muscle cell differentiation and proliferation in outward remodeling during arteriovenous fistula maturation · 2026 · Related
  13. Xbp1s-Negative Tumor B Cells and Pre-Plasmablasts Mediate Therapeutic Proteasome Inhibitor Resistance in Multiple Myeloma · Chungyee Leung-Hagesteijn · 2013 · 416 citations · Cited by this paper
  14. Targeting 15-PGDH/15-oxoETE to mitigate inflammation and senescence in asthma · 2026 · Related
  15. Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice · Satoshi Tanaka · 2016 · 382 citations · Cited by this paper
  16. The irisin-PINK1/Parkin axis plays an essential role in mediating microglial mitophagy: A crucial mechanism for exercise-induced neuroprotection against Parkinson's disease · 2026 · Related
  17. tRF/miR-1280 Suppresses Stem Cell–like Cells and Metastasis in Colorectal Cancer · Bingqing Huang · 2017 · 348 citations · Cited by this paper
  18. RRx-001 induces apoptosis through reactive oxygen species and endoplasmic reticulum stress in Burkitt lymphoma cells by acting as CD47 and c-Myc regulator · 2026 · Related
  19. Depth of Response in Multiple Myeloma: A Pooled Analysis of Three PETHEMA/GEM Clinical Trials · Juan José Lahuerta · 2017 · 322 citations · Cited by this paper
  20. Dysregulation of a family of short noncoding RNAs, tsRNAs, in human cancer · Yuri Pekarsky · 2016 · 265 citations · Cited by this paper
  21. tRF‐Leu‐CAG promotes cell proliferation and cell cycle in non‐small cell lung cancer · Yang Shao · 2017 · 225 citations · Cited by this paper
  22. tRNA-derived RNA fragments in cancer: current status and future perspectives · Mengqian Yu · 2020 · 205 citations · Cited by this paper
  23. NEK2 induces autophagy‐mediated bortezomib resistance by stabilizing Beclin‐1 in multiple myeloma · Jiliang Xia · 2020 · 121 citations · Cited by this paper
  24. Hypoxia‐induced tRNA‐derived fragments, novel regulatory factor for doxorubicin resistance in triple‐negative breast cancer · Yangyang Cui · 2018 · 119 citations · Cited by this paper
  25. MIR145-3ppromotes autophagy and enhances bortezomib sensitivity in multiple myeloma by targetingHDAC4 · Hongkun Wu · 2019 · 108 citations · Cited by this paper
  26. Angiogenin promotes colorectal cancer metastasis via tiRNA production · Siqi Li · 2019 · 107 citations · Cited by this paper
  27. Novel insights into the emerging roles of tRNA-derived fragments in mammalian development · Nicola Guzzi · 2020 · 83 citations · Cited by this paper
  28. Targeting phospho-MARCKS overcomes drug-resistance and induces antitumor activity in preclinical models of multiple myeloma · Yijun Yang · 2014 · 78 citations · Cited by this paper
  29. TCL1 targeting miR-3676 is codeleted with tumor protein p53 in chronic lymphocytic leukemia · Veronica Balatti · 2015 · 74 citations · Cited by this paper
  30. Polymorphisms in the multiple drug resistance protein 1 and in P-glycoprotein 1 are associated with time to event outcomes in patients with advanced multiple myeloma treated with bortezomib and pegylated liposomal doxorubicin · Gabriele Buda · 2010 · 61 citations · Cited by this paper
  31. FOXM1 is a therapeutic target for high-risk multiple myeloma · Chao Gu · 2015 · 58 citations · Cited by this paper
  32. The monomer TEC of blueberry improves NASH by augmenting tRF-47-mediated autophagy/pyroptosis signaling pathway · Juanjuan Zhu · 2022 · 47 citations · Cited by this paper
  33. Antileukemic Activity and Mechanism of Drug Resistance to the Marine Salinispora tropica Proteasome Inhibitor Salinosporamide A (Marizomib) · Denise Niewerth · 2014 · 46 citations · Cited by this paper
  34. A tRNA-derived fragment (tRF-3001b) aggravates the development of nonalcoholic fatty liver disease by inhibiting autophagy · Juanjuan Zhu · 2020 · 34 citations · Cited by this paper
  35. tRNA‐Derived Fragment tRF‐5009A Regulates Autophagy and Degeneration of Cartilage in Osteoarthritis via Targeting mTOR · Zengfa Deng · 2022 · 15 citations · Cited by this paper
  36. tRNA-derived fragments as novel potential biomarkers for relapsed/refractory multiple myeloma · Cong Xu · 2021 · 13 citations · Cited by this paper
  37. tRNA Derivatives in Multiple Myeloma: Investigation of the Potential Value of a tRNA-Derived Molecular Signature · Paraskevi Karousi · 2021 · 11 citations · Cited by this paper
  38. Autophagy and Myeloma · Zhong Zheng · 2020 · 8 citations · Cited by this paper
  39. A Molecular Signature of Three tRNA-Derived RNA Fragments May Discriminate Smoldering from Symptomatic Multiple Myeloma Patients · Paraskevi Karousi · 2019 · 3 citations · Cited by this paper

Source: OpenAlex (CC0)