Research map: PTEN Protein Loss in Diagnostic Prostate Biopsies Is Associated with Gleason Score Upgrading in Radical Prostatectomy

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Papers in this map

  1. Clinical implications of PTEN loss in prostate cancer · Tamara Jamaspishvili · 2018 · 678 citations · Cited by this paper
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  9. Heterogeneity of Gleason grade in multifocal adenocarcinoma of the prostate · Rebecca Arora · 2004 · 308 citations · Cited by this paper
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  11. PTEN Protein Loss and Clinical Outcome from Castration-resistant Prostate Cancer Treated with Abiraterone Acetate · Roberta Ferraldeschi · 2014 · 265 citations · Cited by this paper
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  13. Intratumoral and Intertumoral Genomic Heterogeneity of Multifocal Localized Prostate Cancer Impacts Molecular Classifications and Genomic Prognosticators · Lei Wei · 2016 · 249 citations · Cited by this paper
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  15. HISTOLOGICAL GRADE HETEROGENEITY IN MULTIFOCAL PROSTATE CANCER. BIOLOGICAL AND CLINICAL IMPLICATIONS · Emiel Ruijter · 1996 · 173 citations · Cited by this paper
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  17. Understaging and undergrading of prostate cancer Argument for postoperative radiation as adjuvant therapy · Paul H. Lange · 1983 · 168 citations · Cited by this paper
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  19. The Heterogeneity of Prostate Cancer: A Practical Approach · Yuri Tolkach · 2018 · 160 citations · Cited by this paper
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  21. How reliable is 12-core prostate biopsy procedure in the detection of prostate cancer? · Ege Can Şerefoğlu · 2013 · 155 citations · Cited by this paper
  22. PTEN loss is associated with upgrading of prostate cancer from biopsy to radical prostatectomy · Tamara Levin Lotan · 2014 · 150 citations · Cited by this paper
  23. An Extended 10-Core Transrectal Ultrasonography Guided Prostate Biopsy Protocol Improves the Detection of Prostate Cancer · Saadettin Eskiçorapçı · 2003 · 144 citations · Cited by this paper
  24. Why and Where do We Miss Significant Prostate Cancer with Multi-parametric Magnetic Resonance Imaging followed by Magnetic Resonance-guided and Transrectal Ultrasound-guided Biopsy in Biopsy-naïve Men? · Martijn G. Schouten · 2017 · 144 citations · Cited by this paper
  25. Loss of PTEN expression is associated with increased risk of recurrence after prostatectomy for clinically localized prostate cancer · Alcides Chaux · 2012 · 137 citations · Cited by this paper
  26. Analytic validation of a clinical-grade PTEN immunohistochemistry assay in prostate cancer by comparison with PTEN FISH · Tamara Levin Lotan · 2016 · 93 citations · Cited by this paper
  27. Improving Clinical Risk Stratification at Diagnosis in Primary Prostate Cancer: A Prognostic Modelling Study · Vincent J. Gnanapragasam · 2016 · 89 citations · Cited by this paper
  28. PTEN losses exhibit heterogeneity in multifocal prostatic adenocarcinoma and are associated with higher Gleason grade · Maisa Yoshimoto · 2012 · 80 citations · Cited by this paper
  29. Re-evaluating the concept of “dominant/index tumor nodule” in multifocal prostate cancer · Cheng Huang · 2014 · 78 citations · Cited by this paper
  30. Heterogeneity of PTEN and ERG expression in prostate cancer on core needle biopsies: implications for cancer risk stratification and biomarker sampling · Rajal B. Shah · 2015 · 51 citations · Cited by this paper
  31. Integrated analysis of the genomic instability of PTEN in clinically insignificant and significant prostate cancer · Stephen J. Murphy · 2015 · 48 citations · Cited by this paper
  32. PTEN status assessment in the Johns Hopkins active surveillance cohort · Jeffrey J. Tosoian · 2018 · 26 citations · Cited by this paper
  33. Undergrading and understaging in patients with clinically insignificant prostate cancer who underwent radical prostatectomy · Irai S. Oliveira · 2010 · 24 citations · Cited by this paper
  34. Precise definition of PTEN C-terminal epitopes and its implications in clinical oncology · Janire Mingo · 2019 · 22 citations · Cited by this paper
  35. Clinical Utility and Biologic Implications of Phosphatase and Tensin Homolog (PTEN) and ETS-related Gene (ERG) in Prostate Cancer · David Ullman · 2017 · 20 citations · Cited by this paper
  36. Histopathological evaluation and grading for prostate cancer: current issues and crucial aspects · Vittorio Agosti · 2024 · 17 citations · Cited by this paper
  37. Grading of Multifocal Prostate Cancer Cases in which the Largest Volume and the Highest Grade Do Not Coincide within One Lesion · Kazuhiro Matsumoto · 2021 · 12 citations · Cited by this paper
  38. Temporal Changes in the Pathologic Assessment of Prostate Cancer · Marshall Scott Lucia · 2012 · 7 citations · Cited by this paper
  39. A clinical prostate biopsy dataset with undetected cancer · Eduard Chelebian · 2025 · 6 citations · Cited by this paper

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