Research map: The transplacental transfer of NHC, the active metabolite of molnupiravir, in the ex vivo human placental perfusion model
Back to the article
Papers in this map
- Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis · Florian Kabinger · 2021 · 751 citations · Cited by this paper
- Interplay between cardiomyocytes and nonmyocytes plays a vital role in cardiac metabolism and function: early-phase metabolic syndrome and short QT · 2025 · Related
- An update on COVID-19 and pregnancy · Denise J. Jamieson · 2021 · 470 citations · Cited by this paper
- Association of stromal cell-derived factor 1α and interferon-γ-induced protein 10 with Fontan pathophysiology · 2026 · Related
- Molnupiravir promotes SARS-CoV-2 mutagenesis via the RNA template · Calvin J. Gordon · 2021 · 303 citations · Cited by this paper
- Cost-effectiveness of incretin therapies: a Canadian lens on diabetes, obesity, and emerging indications · 2026 · Related
- The placenta: transcriptional, epigenetic, and physiological integration during development · Emin Maltepe · 2010 · 301 citations · Cited by this paper
- Protective effects of Melissa officinalis ethanolic extract on doxorubicin-induced cardiotoxicity in a rat model · 2025 · Related
- β- d - N 4-hydroxycytidine Inhibits SARS-CoV-2 Through Lethal Mutagenesis But Is Also Mutagenic To Mammalian Cells · Shuntai Zhou · 2021 · 301 citations · Cited by this paper
- Placental hypoxia and oxidative stress responses to smokeless tobacco use in Alaska Native participants in the MAW study · 2026 · Related
- Rat placentation: An experimental model for investigating the hemochorial maternal-fetal interface · Michael J. Soares · 2012 · 229 citations · Cited by this paper
- Variability in agitated saline echocardiography protocols: a cross-sectional analysis of bubble study techniques in echo labs across Alberta, Canada · 2026 · Related
- Molnupiravir, an Oral Antiviral Treatment for COVID-19 · William A. Fischer · 2021 · 220 citations · Cited by this paper
- Redox homeostasis and therapeutic modulation: the central role of oxidative stress and nuclear factor erythroid 2-related factor 2 (Nrf2) activation in systemic diseases and reproductive dysfunction · 2025 · Related
- Morphology and physiology of rat placenta for toxicological evaluation · Satoshi Furukawa · 2018 · 148 citations · Cited by this paper
- THE ASSOCIATION OF ARTERIAL STIFFNESS WITH THE HIGH INCIDENCE OF CARDIAC ARRHYTHMIAS IN PATIENTS WITH PERIPHERAL ARTERIAL DISEASE · 2026 · Related
- Quality assessment of a placental perfusion protocol · Line Mathiesen · 2010 · 119 citations · Cited by this paper
- Deferoxamine alleviates brain ischemia/reperfusion injury through decreasing LAG-3 and α-Syn expression · 2025 · Related
- Maternal-fetal transfer of saquinavir studied in the ex vivo placental perfusion model · François Forestier · 2001 · 63 citations · Cited by this paper
- Metabolic therapy for cardiovascular diseases with propionyl L-carnitine · 2026 · Related
- In vitro perfusion of human placenta · Jean-Claude Challier · 1976 · 57 citations · Cited by this paper
- Review: Toward an integrated evolutionary understanding of the mammalian placenta · Derek E. Wildman · 2011 · 57 citations · Cited by this paper
- Pregnancy as a Risk Factor of Severe COVID-19 · Aleksander Celewicz · 2021 · 52 citations · Cited by this paper
- Molnupiravir: Mechanism of action, clinical, and translational science · Brian M. Maas · 2024 · 50 citations · Cited by this paper
- The maternal-fetal transfer of lamivudine in the ex vivo human placenta · Steven L. Bloom · 1997 · 43 citations · Cited by this paper
- Overview of Drug Transporters in Human Placenta · Michiko Yamashita · 2021 · 41 citations · Cited by this paper
- Remdesivir and EIDD-1931 Interact with Human Equilibrative Nucleoside Transporters 1 and 2: Implications for Reaching SARS-CoV-2 Viral Sanctuary Sites · Siennah R. Miller · 2021 · 39 citations · Cited by this paper
- Multiple SLC and ABC Transporters Contribute to the Placental Transfer of Entecavir · Zhiyuan Ma · 2017 · 38 citations · Cited by this paper
- Equilibrative Nucleoside Transporter 1 (ENT1, SLC29A1) Facilitates Transfer of the Antiretroviral Drug Abacavir across the Placenta · Lukáš Červený · 2018 · 34 citations · Cited by this paper
- Effect of drug efflux transporters on placental transport of antiretroviral agent abacavir · Zuzana Neumanova · 2015 · 34 citations · Cited by this paper
- Evaluation of the mutagenic effects of Molnupiravir and N4 ‐hydroxycytidine in bacterial and mammalian cells by HiFi sequencing · Jaime A. Miranda · 2022 · 30 citations · Cited by this paper
- Expression of Concentrative Nucleoside Transporters (SLC28A) in the Human Placenta: Effects of Gestation Age and Prototype Differentiation-Affecting Agents · Lucie Jirásková · 2018 · 22 citations · Cited by this paper
- Molnupiravir Does Not Induce Mutagenesis in Host Lung Cells during SARS-CoV-2 Treatment · John Maringa Githaka · 2022 · 20 citations · Cited by this paper
- Role of nucleoside transporters in transplacental pharmacokinetics of nucleoside reverse transcriptase inhibitors zidovudine and emtricitabine · Sara Karbanova · 2017 · 18 citations · Cited by this paper
- Pre-Delta, Delta, and Omicron Periods of the Coronavirus Disease 2019 (COVID-19) Pandemic and Health Outcomes During Delivery Hospitalization · Jeffrey Mitchell Carlson · 2023 · 16 citations · Cited by this paper
- Transfer and biotransformation of the COVID-19 prodrug molnupiravir and its metabolite β-D-N4-hydroxycytidine across the blood-placenta barrier · Chun‐Hao Chang · 2023 · 14 citations · Cited by this paper
- Do SARS-CoV-2-Infected Pregnant Women Have Adverse Pregnancy Outcomes as Compared to Non-Infected Pregnant Women? · Syed Nawaz Ahmad · 2022 · 11 citations · Cited by this paper
- Interactions of the Anti-SARS-CoV-2 Agents Molnupiravir and Nirmatrelvir/Paxlovid with Human Drug Transporters · Éva Bakos · 2023 · 8 citations · Cited by this paper
- Human placenta cytidine deaminase: a zinc metalloprotein · Silvia Vincenzetti · 1997 · 1 citation · Cited by this paper
Source: OpenAlex (CC0)