Research map: Aspirin Inhibits the cGAS-STING Signaling Pathway to Ameliorate the Development of Aortic Aneurysm and Dissection

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  1. Broadening horizons: the role of ferroptosis in cancer · Xin Chen · 2021 · 3014 citations · Cited by this paper
  2. Targeting cGAS-STING and Ferroptosis in Aortic Disease: Another Aspirin Discovery · Albert Phillip Owens · 2026 · Cites this paper
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  8. Molecular mechanisms and cellular functions of cGAS–STING signalling · Karl‐Peter Hopfner · 2020 · 2069 citations · Cited by this paper
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  10. The molecular and metabolic landscape of iron and ferroptosis in cardiovascular disease · Xuexian Fang · 2022 · 1108 citations · Cited by this paper
  11. PERK Is Dispensable for Smooth Muscle Cell Phenotype Switching in Atherosclerosis · 2026 · Related
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  14. Vascular Smooth Muscle Cells and Arterial Stiffening: Relevance in Development, Aging, and Disease · Patrick J. Lacolley · 2017 · 741 citations · Cited by this paper
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  16. The epigenetic regulators and metabolic changes in ferroptosis-associated cancer progression · Yuqing Wu · 2020 · 382 citations · Cited by this paper
  17. Neutrophils Exhibit Delayed Spontaneous Apoptosis and Resistance to Regulatory T-Cell–Induced Apoptosis in Patients With Chronic Coronary Syndrome—Brief Report · 2026 · Related
  18. Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity · Jiang Dai · 2019 · 373 citations · Cited by this paper
  19. Interplay of Multipathway Dyslipidemia, Inflammation, and Cholesterol-Lowering Medication in Modifying Abdominal Aortic Aneurysm Risk · 2026 · Related
  20. Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association For European Cardiovascular Pathology: II. Noninflammatory degenerative diseases — nomenclature and diagnostic criteria · Marc K. Halushka · 2016 · 314 citations · Cited by this paper
  21. Prelamin A in an Lmna L648R/L648R Mouse Model Does Not Promote Atherosclerosis or Vascular Smooth Muscle Loss · 2026 · Related
  22. Critical Role of Cytosolic DNA and Its Sensing Adaptor STING in Aortic Degeneration, Dissection, and Rupture · Wei Luo · 2019 · 299 citations · Cited by this paper
  23. Regulation of cGAS–STING signalling and its diversity of cellular outcomes · Zhengyin Zhang · 2025 · 265 citations · Cited by this paper
  24. STING agonist diABZI induces PANoptosis and DNA mediated acute respiratory distress syndrome (ARDS) · Yasmine Messaoud-Nacer · 2022 · 259 citations · Cited by this paper
  25. Combination of the STING Agonist MIW815 (ADU-S100) and PD-1 Inhibitor Spartalizumab in Advanced/Metastatic Solid Tumors or Lymphomas: An Open-Label, Multicenter, Phase Ib Study · Funda Meric‐Bernstam · 2022 · 254 citations · Cited by this paper
  26. Beyond COX-1: the effects of aspirin on platelet biology and potential mechanisms of chemoprevention · Argentina Ornelas · 2017 · 227 citations · Cited by this paper
  27. Vascular Smooth Muscle Cells in Aortic Aneurysm: From Genetics to Mechanisms · Haocheng Lu · 2021 · 212 citations · Cited by this paper
  28. Translational Relevance and Recent Advances of Animal Models of Abdominal Aortic Aneurysm · Jean Nicolas Sénémaud · 2017 · 172 citations · Cited by this paper
  29. STING activation in platelets aggravates septic thrombosis by enhancing platelet activation and granule secretion · Mina Yang · 2023 · 128 citations · Cited by this paper
  30. Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses · Tina M. Sali · 2015 · 126 citations · Cited by this paper
  31. Mitochondrial dysfunction promotes aquaporin expression that controls hydrogen peroxide permeability and ferroptosis · Yuko Takashi · 2020 · 109 citations · Cited by this paper
  32. Mesenchymal stem cell-derived extracellular vesicles protect against abdominal aortic aneurysm formation by inhibiting NET-induced ferroptosis · Liang Chen · 2023 · 106 citations · Cited by this paper
  33. Mitochondrial Damage‐Induced Innate Immune Activation in Vascular Smooth Muscle Cells Promotes Chronic Kidney Disease‐Associated Plaque Vulnerability · Xianjin Bi · 2021 · 102 citations · Cited by this paper
  34. Manganese induces tumor cell ferroptosis through type-I IFN dependent inhibition of mitochondrial dihydroorotate dehydrogenase · Shanlong Zhang · 2022 · 95 citations · Cited by this paper
  35. Ganglioside GM3 Protects Against Abdominal Aortic Aneurysm by Suppressing Ferroptosis · Fangni Zhang · 2023 · 87 citations · Cited by this paper
  36. Targeting macrophage TFEB-14-3-3 epsilon Interface by naringenin inhibits abdominal aortic aneurysm · Yiting Jia · 2022 · 85 citations · Cited by this paper
  37. Kawasaki-like diseases and thrombotic coagulopathy in COVID-19: delayed over-activation of the STING pathway? · Jean‐Marie Berthelot · 2020 · 78 citations · Cited by this paper
  38. Idebenone attenuates ferroptosis by inhibiting excessive autophagy via the ROS-AMPK-mTOR pathway to preserve cardiac function after myocardial infarction · Demin Li · 2023 · 72 citations · Cited by this paper
  39. Gastrodin Inhibits H2O2-Induced Ferroptosis through Its Antioxidative Effect in Rat Glioma Cell Line C6 · Ting Jiang · 2020 · 67 citations · Cited by this paper

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