Research map: Unmasking Wnt-driven HCC: Inhibiting SMYD2 to overcome immune resistance
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Papers in this map
Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma
· Richard S. Finn · 2020 · 7562 citations · Cited by this paper
Rethinking lymphodepleting preconditioning in adoptive T cell therapy for durable tumor control
· 2026 · Related
WNT/β-catenin Pathway Activation Correlates with Immune Exclusion across Human Cancers
· Jason J. Luke · 2019 · 735 citations · Cited by this paper
Depletion of IL-10 in CAR-NK cells augments reprogramming of the tumor microenvironment and ameliorates therapeutic efficacy
· 2026 · Related
Crosstalk between hepatic tumor cells and macrophages via Wnt/β-catenin signaling promotes M2-like macrophage polarization and reinforces tumor malignant behaviors
· Yang Yang · 2018 · 318 citations · Cited by this paper
AGTR1 signaling contributes to tumor immunity and therapy response in non-small cell lung cancer
· 2026 · Related
Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer
· Nicolas Reynoird · 2016 · 89 citations · Cited by this paper
CART-immune-related adverse events after BCMA CAR-T therapy
· 2026 · Related
SMYD2 inhibition–mediated hypomethylation of Ku70 contributes to impaired nonhomologous end joining repair and antitumor immunity
· Ming Tang · 2023 · 32 citations · Cited by this paper
Intraperitoneal delivery of the oncolytic virus CF17 improves tumor immunogenicity and survival in gastric cancer peritoneal metastasis
· 2026 · Related
SMYD2 Promotes Hepatocellular Carcinoma Progression by Reprogramming Glutamine Metabolism via c-Myc/GLS1 Axis
· Kangdi Xu · 2022 · 28 citations · Cited by this paper
Synergistic Cell-Cycle Repression by HDAC/EZH2 Co-Targeting in H3K27-Altered Diffuse Midline Glioma
· 2026 · Related
Natural killer cell-derived extracellular vesicles reprogram cellular human immunity to enhance tumor cytotoxicity
· 2026 · Related
CAR design equips diverse immune cells with unique antigen-specific activation identities
· 2026 · Related
Optimizing CAR T cell therapy in pancreatic cancer through clinically actionable combinations
· 2026 · Related
Strategies to prevent HNSCC by chewing gum delivery of enzymes/antimicrobials to reduce carcinogenic acetaldehyde produced by pathogenic microbes
· 2026 · Related
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