Research map: Overcoming Radiation Resistance: Ferroptosis Induction to Sensitize Solid Tumors to Radiation Therapy

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  1. Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death · Scott J. Dixon · 2012 · 19067 citations · Cited by this paper
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  15. Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice · José Pedro Friedmann Angeli · 2014 · 3792 citations · Cited by this paper
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  17. The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis · Kirill Bersuker · 2019 · 3782 citations · Cited by this paper
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  21. FSP1 is a glutathione-independent ferroptosis suppressor · Sebastian G. Doll · 2019 · 3412 citations · Cited by this paper
  22. Cancer and Radiation Therapy: Current Advances and Future Directions · Rajamanickam Baskar · 2012 · 2896 citations · Cited by this paper
  23. NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis · Matthew B. Dodson · 2019 · 2494 citations · Cited by this paper
  24. CD44: From adhesion molecules to signalling regulators · Helmut Ponta · 2003 · 2411 citations · Cited by this paper
  25. Autophagy promotes ferroptosis by degradation of ferritin · Wen‐Chi Hou · 2016 · 2340 citations · Cited by this paper
  26. Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis · Gina M. DeNicola · 2011 · 2307 citations · Cited by this paper
  27. Phenotypic characterization of human colorectal cancer stem cells · Piero D. Dalerba · 2007 · 2226 citations · Cited by this paper
  28. Ferroptosis as a target for protection against cardiomyopathy · Xuexian Fang · 2019 · 2208 citations · Cited by this paper
  29. Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis · Scott J. Dixon · 2014 · 2121 citations · Cited by this paper
  30. Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy · Joseph Douglas Mancias · 2014 · 2095 citations · Cited by this paper
  31. Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway · Vasanthi S. Viswanathan · 2017 · 2095 citations · Cited by this paper
  32. The role of radiotherapy in cancer treatment · Geoff P. Delaney · 2005 · 1747 citations · Cited by this paper
  33. A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells · Ursula Günthert · 1991 · 1689 citations · Cited by this paper
  34. Iron and cancer: more ore to be mined · Suzy V. Torti · 2013 · 1675 citations · Cited by this paper
  35. Recent Progress in Ferroptosis Inducers for Cancer Therapy · Chen Liang · 2019 · 1657 citations · Cited by this paper
  36. The hazard of accelerated tumor clonogen repopulation during radiotherapy · H. Rodney Withers · 1988 · 1607 citations · Cited by this paper
  37. Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury · Edouard I. Azzam · 2011 · 1570 citations · Cited by this paper
  38. Role of GPX4 in ferroptosis and its pharmacological implication · Tobias Seibt · 2018 · 1558 citations · Cited by this paper
  39. Mechanisms of ferroptosis · Jennifer Yinuo Cao · 2016 · 1542 citations · Cited by this paper

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