Research map: Towards Antimicrobial Formulations of Repurposed Drugs and Cationic Surfactants: Efficacy, Cytotoxicity on Human Cell Lines, and Ecotoxicity in Aquatic Models

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  1. SOS response promotes horizontal dissemination of antibiotic resistance genes · John W. Beaber · 2003 · 1206 citations · Cited by this paper
  2. Integrated Genome Mining, Bacterial Co-Culture Activation, and Peptidomic Analyses Identify Antimicrobial Peptide Candidates from South American Bacteria · 2026 · Related
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  6. Novel Therapeutic Approaches and Alternatives to Antibiotic Therapy for Drug-Resistant Intra-Abdominal Infections · 2026 · Related
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  8. A New Antibacterial Protocol Based on Cymbopogon nardus (L.) Rendle Essential Oil and UV-C Radiation with Potential Application for Hatching Eggs · 2026 · Related
  9. Daphnia magna model in the toxicity assessment of pharmaceuticals: A review · Angelika Tkaczyk‐Wlizło · 2020 · 336 citations · Cited by this paper
  10. Time-Dependent Degradation of Imipenem in Aqueous Solution and Its Impact on Antibacterial Activity · 2026 · Related
  11. Challenges in the management of chronic wound infections · Marco Falcone · 2021 · 334 citations · Cited by this paper
  12. Ceftazidime-Avibactam as Early Empiric Therapy for Gram-Negative Nosocomial Infections: A Risk-Stratified Empiric Use Informed by National AMR Surveillance Data 2024 · 2026 · Related
  13. Culture of skin cells in 3D rather than 2D improves their ability to survive exposure to cytotoxic agents · Tao Sun · 2006 · 306 citations · Cited by this paper
  14. Antibiotic Prescribing Among Inpatients with Ophthalmic Diagnoses: A Decade of Evidence from Two Private-Sector Indian Hospitals · 2026 · Related
  15. Removal of cytostatic drugs from aquatic environment: A review · Jiefeng Zhang · 2013 · 291 citations · Cited by this paper
  16. Synthesis, Antibacterial Evaluation, and Chemometric Profiling of a Vanilloid-Based Compounds Library Active Against Helicobacter pylori · 2026 · Related
  17. Do cytotoxic chemotherapy drugs discharged into rivers pose a risk to the environment and human health? An overview and UK case study · Andrew Charles Johnson · 2007 · 255 citations · Cited by this paper
  18. Impact of Imipenem on Cognitive Function, Anxiety-like Behaviour, Neurogenesis, and Astrogliosis in Pentylenetetrazol-Kindled Rats · 2026 · Related
  19. Combatting bacterial infections by killing persister cells with mitomycin C · Brian W. Kwan · 2015 · 202 citations · Cited by this paper
  20. Clinical and Epidemiological Landscape of Antimicrobial Resistance and Virulence in Streptococcus Species · 2026 · Related
  21. A standardized test to assess the impact of different organic challenges on the antimicrobial activity of antiseptics · Frank-Albert Pitten · 2003 · 132 citations · Cited by this paper
  22. Modification of membrane properties and fatty acids biosynthesis-related genes in Escherichia coli and Staphylococcus aureus: Implications for the antibacterial mechanism of naringenin · Lang‐Hong Wang · 2017 · 130 citations · Cited by this paper
  23. Toxicity of three binary mixtures to Daphnia magna: Comparing chemical modes of action and deviations from conceptual models · Susana Loureiro · 2010 · 117 citations · Cited by this paper
  24. An evidence-based approach to diabetic foot infections · Robert G. Frykberg · 2003 · 101 citations · Cited by this paper
  25. Repurposing the anticancer drug mitomycin C for the treatment of persistent Acinetobacter baumannii infections · Martha Yumiko Cruz-Muñiz · 2016 · 91 citations · Cited by this paper
  26. Friends or enemies? The complicated relationship between Pseudomonas aeruginosa and Staphylococcus aureus · Deborah Bow Yue Yung · 2021 · 88 citations · Cited by this paper
  27. Occurrence and Ecotoxicological Risk Assessment of 14 Cytostatic Drugs in Wastewater · Julia Martı́n · 2014 · 84 citations · Cited by this paper
  28. DNA sequence specificity of mitomycin cross-linking · Sally P. Teng · 1989 · 81 citations · Cited by this paper
  29. The Antibacterial Activity of Lavender Essential Oil Alone and In Combination with Octenidine Dihydrochloride against MRSA Strains · Pawel A. Kwiatkowski · 2019 · 81 citations · Cited by this paper
  30. Low-level exposure of MRSA to octenidine dihydrochloride does not select for resistance · Zainab Al-Doori · 2007 · 76 citations · Cited by this paper
  31. Antibiofilm Effect of Octenidine Hydrochloride on Staphylococcus aureus, MRSA and VRSA · Mary Anne Roshni Amalaradjou · 2014 · 65 citations · Cited by this paper
  32. High-throughput identification and rational design of synergistic small-molecule pairs for combating and bypassing antibiotic resistance · Morgan A. Wambaugh · 2017 · 65 citations · Cited by this paper
  33. Synergistic antibiofilm efficacy of various commercial antiseptics, enzymes and EDTA: a study of Pseudomonas aeruginosa and Staphylococcus aureus biofilms · Elodie Lefebvre · 2016 · 62 citations · Cited by this paper
  34. Repurposed Antimicrobial Combination Therapy: Tobramycin-Ciprofloxacin Hybrid Augments Activity of the Anticancer Drug Mitomycin C Against Multidrug-Resistant Gram-Negative Bacteria · Ronald Domalaon · 2019 · 60 citations · Cited by this paper
  35. Unraveling the mechanism of octenidine and chlorhexidine on membranes: Does electrostatics matter? · Mateusz Rzycki · 2021 · 59 citations · Cited by this paper
  36. Enhanced Antibacterial Activity of Repurposed Mitomycin C and Imipenem in Combination with the Lytic Phage vB_KpnM-VAC13 against Clinical Isolates of Klebsiella pneumoniae · Olga Pacios · 2021 · 56 citations · Cited by this paper
  37. Pseudomonas aeruginosa adapts to octenidine in the laboratory and a simulated clinical setting, leading to increased tolerance to chlorhexidine and other biocides · Matthew J. Shepherd · 2018 · 52 citations · Cited by this paper
  38. The Mitomycin C (MMC)-binding Protein from MMC-producing Microorganisms Protects from the Lethal Effect of Bleomycin: Crystallographic Analysis to Elucidate the Binding Mode of the Antibiotic to the Protein · Narandalai Danshiitsoodol · 2006 · 49 citations · Cited by this paper
  39. Synergism versus Additivity: Defining the Interactions between Common Disinfectants · Daniel J. Noel · 2021 · 47 citations · Cited by this paper

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