Research map: Pamidronate is ineffective for inflammatory-like low back pain associated with Modic type 1 changes: A double-blind, randomised controlled trial

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  1. MRI Findings of Disc Degeneration are More Prevalent in Adults with Low Back Pain than in Asymptomatic Controls: A Systematic Review and Meta-Analysis · Waleed Brinjikji · 2015 · 608 citations · Cited by this paper
  2. Who is waiting to see the surgeon? sociodemographic, clinical characteristics and previous osteoarthritis care of people with knee osteoarthritis referred to public hospitals in Victoria, Australia · 2026 · Related
  3. Handbook of Missing Data Methodology · Geert Molenberghs · 2014 · 360 citations · Cited by this paper
  4. The Association of Movement-Evoked Pain with Cognitive and Emotional Factors: A Cross-Sectional Study · 2026 · Related
  5. Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial · Laura Louise Laslett · 2012 · 304 citations · Cited by this paper
  6. Recovery of daily-life walking after total knee arthroplasty: A two-year longitudinal study and comparison with healthy controls · 2026 · Related
  7. Modic changes: a systematic review of the literature · Yue-Hui Zhang · 2008 · 221 citations · Cited by this paper
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  9. SAPHO syndrome treated with pamidronate: an open-label study of 10 patients · Howard Amital · 2004 · 171 citations · Cited by this paper
  10. Knee extensor muscles of active older adults with knee osteoarthritis are smaller and weaker but not more fatigable than healthy older adults: Relevance to physical function · 2026 · Related
  11. Modic changes—Their associations with low back pain and activity limitation: A systematic literature review and meta-analysis · Christofer Herlin · 2018 · 164 citations · Cited by this paper
  12. Arthroscopically and manually minced cartilage demonstrates lower cell viability and lower proteoglycan deposition compared to isolated chondrons and chondrocytes · 2026 · Related
  13. Modic changes - An evidence-based, narrative review on its patho-physiology, clinical significance and role in chronic low back pain · Vibhu Krishnan Viswanathan · 2020 · 73 citations · Cited by this paper
  14. “A very good program … but I still have the knee problem”: A qualitative study exploring patient acceptability of physiotherapy-led osteoarthritis services · 2026 · Related
  15. Demystifying Opioid Conversion Calculations · 2018 · 54 citations · Cited by this paper
  16. Familial clustering and physiological risk factors associated with intervertebral disc degeneration in a large population-based cohort · 2026 · Related
  17. Efficacy of zoledronic acid for chronic low back pain associated with Modic changes in magnetic resonance imaging · Katri Koivisto · 2014 · 49 citations · Cited by this paper
  18. Preclinical and early clinical safety of intra-articular spheroid adipose-derived stem cells for knee osteoarthritis: A translational study · 2026 · Related
  19. Effect of Zoledronic Acid and Denosumab in Patients With Low Back Pain and Modic Change: A Proof-of-Principle Trial · Guoqi Cai · 2018 · 42 citations · Cited by this paper
  20. Validation of a French version of Roland–Morris questionnaire in chronic low back pain patients · Djamila Zerkak · 2013 · 32 citations · Cited by this paper
  21. Active discopathy: a clinical reality · Margaux Boisson · 2018 · 31 citations · Cited by this paper
  22. A pilot trial of intravenous pamidronate for chronic low back pain · Marco Pappagallo · 2013 · 24 citations · Cited by this paper
  23. The effect of zoledronic acid on type and volume of Modic changes among patients with low back pain · Katri Koivisto · 2017 · 21 citations · Cited by this paper
  24. Minimal important change was on the lower spectrum of previous estimates and responsiveness was sufficient for core outcomes in chronic low back pain · Lars Christian Haugli Bråten · 2022 · 16 citations · Cited by this paper
  25. Oral Zoledronic acid bisphosphonate for the treatment of chronic low back pain with associated Modic changes: A pilot randomized controlled trial · Graham Ka‐Hon Shea · 2022 · 14 citations · Cited by this paper
  26. Efficacy of pamidronate in erosive degenerative disk disease: A pilot study · David Poujol · 2007 · 12 citations · Cited by this paper
  27. Efficacy of a Tumor Necrosis Factor Inhibitor in Chronic Low‐Back Pain With Modic Type 1 Changes: A Randomized Controlled Trial · Elisabeth Gjefsen · 2024 · 11 citations · Cited by this paper
  28. Efficacy and safety of pamidronate in Modic type 1 changes: study protocol for a prospective randomized controlled clinical trial · Stella Cecchetti · 2014 · 8 citations · Cited by this paper
  29. Evaluating Nonoperative Treatment for Low Back Pain in the Presence of Modic Changes: A Systematic Review · Tariq Ziad Issa · 2022 · 7 citations · Cited by this paper
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