Research map: HDAC2 ‐Mediated SMAD7 Stabilisation Activates Wnt/β‐Catenin Signalling to Drive DNA Damage Repair and Cisplatin Resistance in Ovarian Cancer

Back to the article

Papers in this map

  1. HDACs and HDAC Inhibitors in Cancer Development and Therapy · Yixuan Li · 2016 · 1335 citations · Cited by this paper
  2. Pretreatment With BTK Inhibitors Improved the Sensitivity of DLBCL Cells to CAR ‐T Cells in a Coculture System by Downregulating the Polarisation of M2 Macrophages · 2026 · Related
  3. The DNA Damage Response: Implications for Tumor Responses to Radiation and Chemotherapy · MICHAEL D. GOLDSTEIN · 2014 · 614 citations · Cited by this paper
  4. GGAs : Regulation of Multiple Sorting Pathways and Potential Association With Human Diseases · 2026 · Related
  5. Ovarian Cancer · Giuseppe Davide Caruso · 2025 · 282 citations · Cited by this paper
  6. Exploring the Potential of Calebin‐A in Targeting Obesity‐Related Genes and Pathways · 2026 · Related
  7. Drug resistance in ovarian cancer: from mechanism to clinical trial · Ling Wang · 2024 · 264 citations · Cited by this paper
  8. Superoxide Dismutase–Centered Modulation by Curcumin in Cardiovascular Diseases: Mechanistic Insights and Translational Implications · 2026 · Related
  9. Wnt/β-catenin signalling in ovarian cancer: Insights into its hyperactivation and function in tumorigenesis · Vu H. Nguyen · 2019 · 227 citations · Cited by this paper
  10. PGK1 Drives Glial Glycolytic Reprogramming to Mediate Isoflurane‐Induced Cognitive Impairment in Aged Mice · 2026 · Related
  11. The Balance between Acetylation and Deacetylation Controls Smad7 Stability · Maria Simonsson · 2005 · 187 citations · Cited by this paper
  12. FTO ‐Catalysed Demethylation of LUR1 mRNA Suppresses Macrophage Lipid Accumulation and Aortic Atherosclerosis · 2026 · Related
  13. Targeting DNA Damage Response and Repair to Enhance Therapeutic Index in Cisplatin-Based Cancer Treatment · Robert Kiss · 2021 · 147 citations · Cited by this paper
  14. The STAT3‐CCND2 Axis Drives a Proliferative Metaplastic Precursor Population in Gastric Intestinal Metaplasia · 2026 · Related
  15. Nuclear Regulation of Wnt/β-Catenin Signaling: It’s a Complex Situation · Christin C. Anthony · 2020 · 132 citations · Cited by this paper
  16. Potential Relationship Between YTHDF3 and CFTR in Myocardial Ischemia–Reperfusion Injury · 2026 · Related
  17. The Dual Role of Smad7 in the Control of Cancer Growth and Metastasis · Carmine Stolfi · 2013 · 103 citations · Cited by this paper
  18. circFOXP1 Promotes Pancreatic Ductal Adenocarcinoma Progression Through Regulating EREG / MAPK / ERK Axis · 2026 · Related
  19. HDAC-targeting epigenetic modulators for cancer immunotherapy · Binbin Cheng · 2024 · 103 citations · Cited by this paper
  20. KATP Channel Expression Determines ONC212 Sensitivity via Mitochondrial Dysfunction and PERK / ATF4 / CHOP Activation in Glioblastoma · 2026 · Related
  21. Weighted gene co-expression network analysis and connectivity map identifies lovastatin as a treatment option of gastric cancer by inhibiting HDAC2 · Li Zhang · 2018 · 81 citations · Cited by this paper
  22. HDAC2 as a target for developing anti-cancer drugs · Hyein Jo · 2023 · 66 citations · Cited by this paper
  23. Valproic acid (VPA) enhances cisplatin sensitivity of non-small cell lung cancer cells via HDAC2 mediated down regulation of ABCA1 · Jianhui Chen · 2016 · 55 citations · Cited by this paper
  24. SMAD7: a timer of tumor progression targeting TGF-β signaling · Lingyu Luo · 2014 · 53 citations · Cited by this paper
  25. β-Hydroxybutyrate enhances the cytotoxic effect of cisplatin via the inhibition of HDAC/survivin axis in human hepatocellular carcinoma cells · Daisuke Mikami · 2019 · 41 citations · Cited by this paper
  26. MicroRNA-30e-3p reduces coronary microembolism-induced cardiomyocyte pyroptosis and inflammation by sequestering HDAC2 from the SMAD7 promoter · Rixin Dai · 2023 · 15 citations · Cited by this paper
  27. A narrative review of epigenetic marker in H3K27ac and its emerging potential as a therapeutic target in cancer · Meizi Zhu · 2025 · 15 citations · Cited by this paper
  28. Coordinated protein modules define DNA damage responses to carboplatin at single-cell resolution in human ovarian carcinoma models · Jacob S. Bedia · 2025 · 2 citations · Cited by this paper

Source: OpenAlex (CC0)