Research map: Safety, Tolerability, Pharmacokinetics, Food Effect of Ribitol, and Its Effect on QTcF in Healthy Adults: First‐in‐Human, Randomized, Double‐Blind (Sponsor Unblinded), Placebo‐Controlled Studies

Papers in this map

1. Robust Locally Weighted Regression and Smoothing Scatterplots · William S. Cleveland · 1979 · 11132 citations · Cited by this paper
2. Thorough QT Study on the Effect of Therapeutic and Supratherapeutic Dosing of Givinostat in Healthy Volunteers · 2026 · Related
3. Smoothing Parameter Selection in Nonparametric Regression Using an Improved Akaike Information Criterion · Clifford M. Hurvich · 1998 · 1266 citations · Cited by this paper
4. Distributed Manufacturing, Foreign Establishments, and Why the FDA's New Proposed Rule Matters to Clinical Pharmacology · 2026 · Related
5. Mutations in the Fukutin-Related Protein Gene (FKRP) Cause a Form of Congenital Muscular Dystrophy with Secondary Laminin α2 Deficiency and Abnormal Glycosylation of α-Dystroglycan · Martin Brockington · 2001 · 605 citations · Cited by this paper
6. Pharmacokinetics, Bioequivalence, and Safety Evaluation of Two Voriconazole Tablets in Healthy Chinese Volunteers · 2026 · Related
7. Scientific white paper on concentration-QTc modeling · Christine E. Garnett · 2017 · 258 citations · Cited by this paper
8. Pharmacokinetics and Bioequivalence of Tamsulosin Hydrochloride Extended‐Release Capsules in Healthy Chinese Volunteers: A Randomized, Open‐Label, Crossover Study Under Fasting and Fed Conditions · 2026 · Related
9. Abnormalities in α-Dystroglycan Expression in MDC1C and LGMD2I Muscular Dystrophies · S. Brown · 2004 · 177 citations · Cited by this paper
10. Pharmacokinetic Interaction Between Atorvastatin and Hybutimibe in Healthy Chinese Volunteers · 2026 · Related
11. ISPD produces CDP-ribitol used by FKTN and FKRP to transfer ribitol phosphate onto α-dystroglycan · Isabelle Gerin · 2016 · 148 citations · Cited by this paper
12. Single‐Dose Pharmacokinetic Assessment of TNX‐102 SL (Cyclobenzaprine HCl Sublingual Tablets): Results From Randomized, Open‐Label Studies in Healthy Volunteers · 2026 · Related
13. The Classification, Natural History and Treatment of the Limb Girdle Muscular Dystrophies · Alexander Peter Murphy · 2015 · 120 citations · Cited by this paper
14. From Reflection to Acceleration: Clinical Pharmacology’s 2025 Lessons and 2026 Opportunities · 2026 · Related
15. d-ribose in glycation and protein aggregation · Wei Yan · 2012 · 114 citations · Cited by this paper
16. Pharmacokinetic Comparability of ABP 654, a Biosimilar to Ustekinumab, Administered Either via Prefilled Syringe or Autoinjector in Healthy Adults: Results from a Randomized, Open‐Label, Parallel‐Group Study · 2026 · Related
17. Spectrum of Brain Changes in Patients With Congenital Muscular Dystrophy and FKRP Gene Mutations · Eugenio Maria Mercuri · 2006 · 105 citations · Cited by this paper
18. Pharmacokinetics and Safety of VV116 in Subjects With Mild or Moderate Hepatic Impairment Compared With Healthy Controls: A Phase I, Open‐Label Study · 2026 · Related
19. Ribitol restores functionally glycosylated α-dystroglycan and improves muscle function in dystrophic FKRP-mutant mice · Marcela P. Cataldi · 2018 · 100 citations · Cited by this paper
20. A Phase 1 Bioequivalence Study to Assess the Pharmacokinetics, Safety and Tolerability of Guselkumab After a Single‐Dose Administration via Two Subcutaneous Injection Devices in Healthy Volunteers · 2026 · Related
21. Global FKRP Registry: observations in more than 300 patients with Limb Girdle Muscular Dystrophy R9 · Lindsay B. Murphy · 2020 · 45 citations · Cited by this paper
22. D‑ribose: Potential clinical applications in congestive heart failure and diabetes, and its complications (Review) · Shuai Li · 2021 · 23 citations · Cited by this paper
23. A Randomized Thorough QT Trial Using Concentration‐QT Analysis to Evaluate the Effects of Centanafadine on Cardiac Repolarization · Osman S. Turkoglu · 2025 · 1 citation · Cited by this paper

Source: OpenAlex (CC0)