Research map: Dieckol suppresses lipid accumulation and promotes thermogenic markers in 3T3-L1 adipocytes via ERK/p38 MAPK signaling

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  1. Obesity, Oxidative Stress, Adipose Tissue Dysfunction, and the Associated Health Risks: Causes and Therapeutic Strategies · Prasenjit Manna · 2015 · 1168 citations · Cited by this paper
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  23. Nrf2-Mediated HO-1 Induction Coupled with the ERK Signaling Pathway Contributes to Indirect Antioxidant Capacity of Caffeic Acid Phenethyl Ester in HepG2 Cells · Jin‐Kyoung Kim · 2014 · 119 citations · Cited by this paper
  24. β-Sitosterol Circumvents Obesity Induced Inflammation and Insulin Resistance by down-Regulating IKKβ/NF-κB and JNK Signaling Pathway in Adipocytes of Type 2 Diabetic Rats · Selvaraj Jayaraman · 2021 · 117 citations · Cited by this paper
  25. The Role of the Dysregulated JNK Signaling Pathway in the Pathogenesis of Human Diseases and Its Potential Therapeutic Strategies: A Comprehensive Review · Huaying Yan · 2024 · 106 citations · Cited by this paper
  26. The critical role of JNK in the ER‐mitochondrial crosstalk during apoptotic cell death · Gaurav Verma · 2011 · 101 citations · Cited by this paper
  27. The Interplay Between Adipose Tissue and Vasculature: Role of Oxidative Stress in Obesity · Yawen Zhou · 2021 · 101 citations · Cited by this paper
  28. Dieckol, a phlorotannin isolated from a brown seaweed, Ecklonia cava, inhibits adipogenesis through AMP-activated protein kinase (AMPK) activation in 3T3-L1 preadipocytes · Seok‐Chun Ko · 2013 · 100 citations · Cited by this paper
  29. Protective effect of tea polyphenols on renal ischemia/reperfusion injury via suppressing the activation of TLR4/NF-κB p65 signal pathway · Yanwei Li · 2014 · 92 citations · Cited by this paper
  30. Multifaceted Role of PRDM Proteins in Human Cancer · Amelia Casamassimi · 2020 · 79 citations · Cited by this paper
  31. Feeding-induced hepatokine, Manf, ameliorates diet-induced obesity by promoting adipose browning via p38 MAPK pathway · Tong Wu · 2021 · 74 citations · Cited by this paper
  32. Irisin reverses insulin resistance in C2C12 cells via the p38-MAPK-PGC-1α pathway · Xiao Ye · 2019 · 72 citations · Cited by this paper
  33. A novel dual-targeted rosiglitazone-loaded nanoparticle for the prevention of diet-induced obesity via the browning of white adipose tissue · Ryu Hiradate · 2020 · 71 citations · Cited by this paper
  34. Dieckol, a major phlorotannin in Ecklonia cava, suppresses lipid accumulation in the adipocytes of high‐fat diet‐fed zebrafish and mice: Inhibition of early adipogenesis via cell‐cycle arrest and AMPKα activation · Hyeon‐Son Choi · 2015 · 64 citations · Cited by this paper
  35. Oral Intake of Rosiglitazone Promotes a Central Antihypertensive Effect Via Upregulation of Peroxisome Proliferator-Activated Receptor-γ and Alleviation of Oxidative Stress in Rostral Ventrolateral Medulla of Spontaneously Hypertensive Rats · Samuel H.H. Chan · 2010 · 62 citations · Cited by this paper
  36. Anti-hyperlipidemic Effect of Polyphenol Extract (SeapolynolTM) and Dieckol Isolated from Ecklonia cava in in vivo and in vitro Models · A-Reum Yeo · 2012 · 56 citations · Cited by this paper
  37. The PPARγ agonist rosiglitazone promotes the induction of brite adipocytes, increasing β-adrenoceptor-mediated mitochondrial function and glucose uptake · Jon Merlin · 2017 · 56 citations · Cited by this paper
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