Research map: Cellular Senescence in Diabetic Cardiomyopathy: Mechanistic Insights and Therapeutic Perspectives

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  1. In vivo partial reprogramming alters age-associated molecular changes during physiological aging in mice · Kristen C. Browder · 2022 · 253 citations · Cited by this paper
  2. Beyond Branch Patency: Timing, Bleeding Phenotype, and Organ Risk in Antithrombotic Therapy After Branched EVAR · 2026 · Related
  3. Interconnection between cardiovascular, renal and metabolic disorders: A narrative review with a focus on Japan · Takashi Kadowaki · 2022 · 190 citations · Cited by this paper
  4. Circulating Circ_0089762 Predicts Adverse Outcomes in Acute Myocardial Infarction Via Regulating miR‑938/STAT3‑Mediated Endothelial Dysfunction · 2026 · Related
  5. Lipids and lipid metabolism in cellular senescence: Emerging targets for age-related diseases · Qing Zeng · 2024 · 178 citations · Cited by this paper
  6. Guideline-directed Low-density Lipoprotein Cholesterol Management After Acute Coronary Syndrome in Patients With Mental Illness: a Population-based Study · 2026 · Related
  7. Targeting Cardiac Stem Cell Senescence to Treat Cardiac Aging and Disease · Eleonora Cianflone · 2020 · 160 citations · Cited by this paper
  8. Reflections on Oral Beta Blocker Therapy and Long-term Outcomes after Myocardial Infarction in Preserved Left Ventricular Function · 2026 · Related
  9. Resveratrol reduces ROS-induced ferroptosis by activating SIRT3 and compensating the GSH/GPX4 pathway · Xingjie Wang · 2023 · 156 citations · Cited by this paper
  10. Sennoside A Ameliorates Myocardial Fibrosis After Myocardial Infarction by Binding to KDM4B and Regulates IRX2 Expression · 2026 · Related
  11. The regulatory roles of p53 in cardiovascular health and disease · Hongbo Men · 2020 · 140 citations · Cited by this paper
  12. Hyperuricemia and Hypoxic Pulmonary Hypertension: Pathogenic Links, Clinical Evidence, and Emerging Therapeutic Insights · 2026 · Related
  13. Multi‐omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming · Dafni Chondronasiou · 2022 · 140 citations · Cited by this paper
  14. Aspirin Instead of Clopidogrel after Percutaneous Coronary Intervention in Atrial Fibrillation: More than just an Option · 2026 · Related
  15. Streptozotocin-Induced Type 1 and 2 Diabetes Mellitus Mouse Models Show Different Functional, Cellular and Molecular Patterns of Diabetic Cardiomyopathy · Fabiola Marino · 2023 · 115 citations · Cited by this paper
  16. Possible clinical drug interactions between ticagrelor and concomitant medications: for adverse drug event monitoring in real-world · 2026 · Related
  17. Inhibition of p53 prevents diabetic cardiomyopathy by preventing early-stage apoptosis and cell senescence, reduced glycolysis, and impaired angiogenesis · Junlian Gu · 2018 · 112 citations · Cited by this paper
  18. Targeting SIRT3 in Diabetic Cardiomyopathy: Mechanism-Based Therapeutic Strategies · 2026 · Related
  19. Diabetes-Induced Cellular Senescence and Senescence-Associated Secretory Phenotype Impair Cardiac Regeneration and Function Independently of Age · Fabiola Marino · 2022 · 105 citations · Cited by this paper
  20. BDH1 Protects against Diabetic Cardiomyopathy by Improving Mitochondrial Function and Suppressing Cardiomyocyte Apoptosis Via Activation of the AKT/GSK3β Pathway · 2026 · Related
  21. Cardiac cell senescence: molecular mechanisms, key proteins and therapeutic targets · Yi Luan · 2024 · 104 citations · Cited by this paper
  22. Thymus involution sets the clock of the aging T-cell landscape: Implications for declined immunity and tissue repair · Yehezqel Elyahu · 2020 · 99 citations · Cited by this paper
  23. Cell models for Alzheimer’s and Parkinson’s disease: At the interface of biology and drug discovery · Sandra Cetin · 2022 · 86 citations · Cited by this paper
  24. BMP-7 Attenuates Inflammation-Induced Pyroptosis and Improves Cardiac Repair in Diabetic Cardiomyopathy · Ibrahim Elmadbouh · 2021 · 83 citations · Cited by this paper
  25. SASP Modulation for Cellular Rejuvenation and Tissue Homeostasis: Therapeutic Strategies and Molecular Insights · Saud Alqahtani · 2025 · 80 citations · Cited by this paper
  26. Recognizing Degenerative Aging as a Treatable Medical Condition: Methodology and Policy · Ilia Stambler · 2017 · 68 citations · Cited by this paper
  27. TFEB is a central regulator of the aging process and age-related diseases · Samuel Abokyi · 2023 · 57 citations · Cited by this paper
  28. Glucose‐induced oxidative stress and accelerated aging in endothelial cells are mediated by the depletion of mitochondrial SIRTs · Jieting Liu · 2020 · 55 citations · Cited by this paper
  29. Subcellular structure, heterogeneity, and plasticity of senescent cells · Thais Cardoso Bitencourt · 2024 · 48 citations · Cited by this paper
  30. Cell senescence in cardiometabolic diseases · Mandy O. J. Grootaert · 2024 · 44 citations · Cited by this paper
  31. Multimodality imaging approach to left ventricular dysfunction in diabetes: an expert consensus document from the European Association of Cardiovascular Imaging · Thomas Hugh Marwick · 2021 · 41 citations · Cited by this paper
  32. Targeting mitochondrial quality control for diabetic cardiomyopathy: Therapeutic potential of hypoglycemic drugs · Yutong Zhou · 2023 · 41 citations · Cited by this paper
  33. A new understanding of GHSR1a——independent of ghrelin activation · Xue Xiao · 2020 · 38 citations · Cited by this paper
  34. Unraveling and Targeting Myocardial Regeneration Deficit in Diabetes · Claudia Molinaro · 2022 · 37 citations · Cited by this paper
  35. Circular RNAs: Promising Biomarkers for Age-related Diseases · Yanhong Pan · 2020 · 36 citations · Cited by this paper
  36. The yin and yang faces of the mitochondrial deacetylase sirtuin 3 in age-related disorders · Pedro Gomes · 2019 · 35 citations · Cited by this paper
  37. Suppression of FOXO1 attenuates inflamm‐aging and improves liver function during aging · Wanbao Yang · 2023 · 35 citations · Cited by this paper
  38. Targeting epigenetics in diabetic cardiomyopathy: Therapeutic potential of flavonoids · Yutong Zhou · 2022 · 34 citations · Cited by this paper
  39. Unraveling the epigenetic fabric of type 2 diabetes mellitus: pathogenic mechanisms and therapeutic implications · Cham Jazieh · 2024 · 31 citations · Cited by this paper

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