Research map: Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications

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  1. A global reference for human genetic variation · Corresponding authors · 2015 · 20479 citations · Cited by this paper
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  7. Dolutegravir plus Abacavir–Lamivudine for the Treatment of HIV-1 Infection · Sharon Lynn Walmsley · 2013 · 894 citations · Cited by this paper
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  17. Higher rates of neuropsychiatric adverse events leading to dolutegravir discontinuation in women and older patients · Christian Hoffmann · 2016 · 292 citations · Cited by this paper
  18. Pharmacogenetics of plasma dolutegravir exposure during 1-month rifapentine/isoniazid treatment of latent tuberculosis · 2025 · Related
  19. In Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase Inhibitor · Melinda J. Reese · 2012 · 252 citations · Cited by this paper
  20. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Atazanavir Prescribing · RS Gammal · 2015 · 232 citations · Cited by this paper
  21. Pharmacogenomics · Dan M. Roden · 2011 · 223 citations · Cited by this paper
  22. Intolerance of dolutegravir-containing combination antiretroviral therapy regimens in real-life clinical practice · Mark G. J. de Boer · 2016 · 183 citations · Cited by this paper
  23. PXR: A Xenobiotic Receptor of Diverse Function Implicated in Pharmacogenetics · Bin Zhang · 2008 · 159 citations · Cited by this paper
  24. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters · S P H Alexander · 2021 · 153 citations · Cited by this paper
  25. Emerging roles for folate and related B-vitamins in brain health across the lifecycle · C. McGarel · 2014 · 144 citations · Cited by this paper
  26. Adverse events of raltegravir and dolutegravir · Luigia Elzi · 2017 · 125 citations · Cited by this paper
  27. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Nuclear hormone receptors · S P H Alexander · 2021 · 122 citations · Cited by this paper
  28. Neuropsychiatric Adverse Events with Dolutegravir and Other Integrase Strand Transfer Inhibitors · Christian Hoffmann · 2019 · 116 citations · Cited by this paper
  29. CYP2B6 Genotype and Weight Gain Differences Between Dolutegravir and Efavirenz · Rulan Griesel · 2020 · 89 citations · Cited by this paper
  30. Pharmacogenomic variants have larger effect sizes than genetic variants associated with other dichotomous complex traits · Joseph Maranville · 2015 · 80 citations · Cited by this paper
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  32. Overview of Genotyping Technologies and Methods · Ingrid Skelton Kockum · 2023 · 59 citations · Cited by this paper
  33. Evaluation of the Effect of UGT1A1 Polymorphisms on Dolutegravir Pharmacokinetics · Shuguang Chen · 2013 · 58 citations · Cited by this paper
  34. Efavirenz Pharmacogenetics and Weight Gain Following Switch to Integrase Inhibitor–Containing Regimens · Michael A. Leonard · 2020 · 56 citations · Cited by this paper
  35. Pharmacokinetics of dolutegravir 100 mg once daily with rifampicin · Xinzhu Wang · 2019 · 50 citations · Cited by this paper
  36. Lack of an association between clinical INSTI-related body weight gain and direct interference with MC4 receptor (MC4R), a key central regulator of body weight · Carrie McMahon · 2020 · 40 citations · Cited by this paper
  37. High plasma concentrations of dolutegravir in patients with ABCG2 genetic variants · K. Tsuchiya · 2017 · 35 citations · Cited by this paper
  38. SLC22A2 variants and dolutegravir levels correlate with psychiatric symptoms in persons with HIV · Alberto Borghetti · 2018 · 31 citations · Cited by this paper
  39. Conference Scene: The Great Debate: Genome-Wide Association Studies in Pharmacogenetics Research, Good or Bad? · Kent R. Bailey · 2010 · 17 citations · Cited by this paper

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