Research map: The neuroimmune axis of Alzheimer’s disease

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Papers in this map

  1. Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families · Elizabeth H. Corder · 1993 · 9586 citations · Cited by this paper
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  3. Neuroinflammation in Alzheimer’s and Parkinson’s diseases: pathogenic mechanisms and therapeutic strategies · Qin-qin Wang · 2026 · 1 citation · Related
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  6. Ginsenoside Rg2 attenuates Alzheimer-like phenotypes in 3xTg-AD mice: associations with gut microbiota and brain metabolomic profiles · Ziqi Liu · 2026 · Related
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  10. A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease · Hadas Keren‐Shaul · 2017 · 5894 citations · Cited by this paper
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  12. Circulating tumor DNA precision oncology enables effective and sensitive molecular diagnostics and actionable target detection in pediatric solid tumors - the INFORM experience · 2026 · Related
  13. Lecanemab in Early Alzheimer’s Disease · Christopher H. van Dyck · 2022 · 5709 citations · Cited by this paper
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  15. Integrative stratification of response to immunotherapy using host and microbial signatures in patients with advanced non-small cell lung cancer · 2026 · Related
  16. Sleep Drives Metabolite Clearance from the Adult Brain · Lulu Xie · 2013 · 5529 citations · Cited by this paper
  17. The role of peripheral inflammatory insults in Alzheimer’s disease: a review and research roadmap · Keenan A. Walker · 2023 · 113 citations · Cites this paper
  18. Cell type-specific contextualisation of the human phenome: towards the systematic treatment of all rare diseases · 2026 · Related
  19. Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing · Brian W. Kunkle · 2019 · 3277 citations · Cited by this paper
  20. Decoding microglial immunometabolism: a new frontier in Alzheimer's disease research · Eun Sun Jung · 2025 · 106 citations · Cites this paper
  21. Long-read transcriptome sequencing and Drosophila-based functional validation reveal novel gene fusions in fusion panel-negative gliomas · 2026 · Related
  22. The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases · Susanne Krasemann · 2017 · 3194 citations · Cited by this paper
  23. Advances in the study of IL-17 in neurological diseases and mental disorders · Yu Lu · 2023 · 71 citations · Cites this paper
  24. Microbiota and Alzheimer’s disease: mechanistic insights from a multi-organ perspective · 2026 · Related
  25. Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders · Melanie D. Sweeney · 2018 · 3140 citations · Cited by this paper
  26. A single-cell atlas deconstructs heterogeneity across multiple models in murine traumatic brain injury and identifies novel cell-specific targets · Ruchira Menka Jha · 2024 · 71 citations · Cites this paper
  27. Glycosylation in neuroinflammation: mechanisms, implications, and therapeutic strategies for neurodegenerative diseases · 2025 · Related
  28. Alzheimer disease · David S. Knopman · 2021 · 2558 citations · Cited by this paper
  29. The Impact of Routine Vaccinations on Alzheimer’s Disease Risk in Persons 65 Years and Older: A Claims-Based Cohort Study using Propensity Score Matching · Kristofer Harris · 2023 · 59 citations · Cites this paper
  30. Non-Cognitive Symptoms in Alzheimer’s Disease and Their Likely Impact on Patient Outcomes. A Scoping Review · 2025 · Related
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  32. Peripheral inflammatory biomarkers are associated with cognitive function and dementia: Framingham Heart Study Offspring cohort · Jiachen Chen · 2023 · 56 citations · Cites this paper
  33. Blood-Brain Barrier Breakdown in the Aging Human Hippocampus · Axel Montagne · 2015 · 2171 citations · Cited by this paper
  34. Immune mechanisms and shared immune targets in neurodegenerative diseases · Howard L. Weiner · 2024 · 55 citations · Cites this paper
  35. Neuroinflammation and M2 microglia: the good, the bad, and the inflamed · Jonathan D. Cherry · 2014 · 1778 citations · Cited by this paper
  36. Interleukin-6 deficiency reduces neuroinflammation by inhibiting the STAT3-cGAS-STING pathway in Alzheimer’s disease mice · Min Liu · 2024 · 54 citations · Cites this paper
  37. Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment · Jonas Schulte-Schrepping · 2020 · 1640 citations · Cited by this paper
  38. Tipping points in neurodegeneration · Mikael Simons · 2023 · 53 citations · Cites this paper
  39. Functional aspects of meningeal lymphatics in ageing and Alzheimer’s disease · Sandro Dá Mesquita · 2018 · 1486 citations · Cited by this paper

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