Research map: S14G-humanin (HNG) ameliorates diabetic nephropathy tubular injury by inhibiting Z-DNA/ZBP1-mediated necroptosis

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  1. Necroptosis, pyroptosis and apoptosis: an intricate game of cell death · Damien Bertheloot · 2021 · 2225 citations · Cited by this paper
  2. Targeting annexin A1 in kidney diseases: a novel therapeutic avenue · Jun Deng · 2026 · Cites this paper
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  18. Structure of the DLM-1-Z-DNA complex reveals a conserved family of Z-DNA-binding proteins. · Thomas Schwartz · 2001 · 317 citations · Cited by this paper
  19. Role of Abca7-related microglial responses in linking type 2 diabetes mellitus to Alzheimer's disease progression: Evidence from single-cell transcriptomic analysis and experimental validation in animal and cell models · 2026 · Related
  20. ZBP1: Innate Sensor Regulating Cell Death and Inflammation · Teneema Kuriakose · 2017 · 314 citations · Cited by this paper
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  23. Z-DNA and Z-RNA in human disease · Alan G. Herbert · 2018 · 259 citations · Cited by this paper
  24. Detailed Characterization of Neuroprotection by a Rescue Factor Humanin against Various Alzheimer's Disease-Relevant Insults · Yuichi Hashimoto · 2001 · 219 citations · Cited by this paper
  25. The Biology of Left-handed Z-DNA · Alan G. Herbert · 1996 · 200 citations · Cited by this paper
  26. Necroptosis contributes to chronic inflammation and fibrosis in aging liver · Sabira Mohammed · 2021 · 196 citations · Cited by this paper
  27. Necroptosis in Immuno-Oncology and Cancer Immunotherapy · Jenny Sprooten · 2020 · 174 citations · Cited by this paper
  28. Acute Humanin Therapy Attenuates Myocardial Ischemia and Reperfusion Injury in Mice · Radhika H. Muzumdar · 2010 · 162 citations · Cited by this paper
  29. Bilirubin and biliverdin protect rodents against diabetic nephropathy by downregulating NAD(P)H oxidase · Masakazu Fujii · 2010 · 155 citations · Cited by this paper
  30. MLKL: Functions beyond serving as the Executioner of Necroptosis · Chaoning Zhan · 2021 · 154 citations · Cited by this paper
  31. Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease · Amine Majdi · 2019 · 150 citations · Cited by this paper
  32. Platelet Microparticles Mediate Glomerular Endothelial Injury in Early Diabetic Nephropathy · Yang Zhang · 2018 · 130 citations · Cited by this paper
  33. ZBP1: A Powerful Innate Immune Sensor and Double-Edged Sword in Host Immunity · Hao Yu · 2022 · 108 citations · Cited by this paper
  34. PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum–Mitochondria Contact and Mitophagy in Diabetic Nephropathy · Chenrui Li · 2022 · 107 citations · Cited by this paper
  35. Baicalin inhibits PANoptosis by blocking mitochondrial Z-DNA formation and ZBP1-PANoptosome assembly in macrophages · Yi-Ping You · 2024 · 91 citations · Cited by this paper
  36. Angiotensin(1–7) attenuates the progression of streptozotocin-induced diabetic renal injury better than angiotensin receptor blockade · Kai Zhang · 2014 · 75 citations · Cited by this paper
  37. The necroptosis cell death pathway drives neurodegeneration in Alzheimer’s disease · Sriram Balusu · 2024 · 65 citations · Cited by this paper
  38. Chronic treatment with the mitochondrial peptide humanin prevents age-related myocardial fibrosis in mice · Qing Qin · 2018 · 58 citations · Cited by this paper
  39. Receptor activator of NF-κB mediates podocyte injury in diabetic nephropathy · Guibao Ke · 2021 · 58 citations · Cited by this paper

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