Research map: Ferroptosis and Chinese Medicine in Rheumatoid Arthritis: Mechanisms and Emerging Intervention Strategies

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  1. Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death · Scott J. Dixon · 2012 · 19067 citations · Cited by this paper
  2. Fucoidan: Structure–activity relationships, molecular mechanisms, and nanotherapeutic applications with perspectives from Traditional Chinese Medicine · 2026 · Related
  3. Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease · Brent R. Stockwell · 2017 · 7879 citations · Cited by this paper
  4. Synergistic, additive, and antagonistic modulation of inflammation and immunity by multi-compound traditional Chinese medicine formulas · 2026 · Related
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  7. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin · Elizabeta Nemeth · 2004 · 2176 citations · Cited by this paper
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  9. Fibroblast‐like synoviocytes: key effector cells in rheumatoid arthritis · Beatrix Bartók · 2009 · 1947 citations · Cited by this paper
  10. Mechanisms of jinbei oral liquid in treating idiopathic pulmonary fibrosis via microecology-metabolism-immune regulation · 2026 · Related
  11. Lipid peroxidation in cell death · Michael M. Gaschler · 2017 · 1861 citations · Cited by this paper
  12. Quercetin, kaempferol, baicalein, and ellagic acid in Guizhi Fuling Wan suppress Glioblastoma by inducing p21-mediated cell cycle arrest and mitochondrial apoptosis · 2026 · Related
  13. Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials · N Bhala · 2013 · 1807 citations · Cited by this paper
  14. Mechanistic pharmacology of TCM-derived bioactive compounds in Alzheimer’s disease: molecular targets, standardization, and translational insights · 2026 · Related
  15. The Metabolic Underpinnings of Ferroptosis · Jiashuo Zheng · 2020 · 1386 citations · Cited by this paper
  16. Unraveling Nature's Hidden Secret: Exploring the Botanical Therapeutics and Multifunctional Pharmacological Potentials of Snake Melon (Cucumis melo var. flexuosus) · 2026 · Related
  17. GPX4 at the Crossroads of Lipid Homeostasis and Ferroptosis · Giovanni C. Forcina · 2019 · 1099 citations · Cited by this paper
  18. From Qi to synapse: A systems-based review of Traditional Chinese Medicine in the treatment of major depressive disorder · 2026 · Related
  19. ROS-induced lipid peroxidation modulates cell death outcome: mechanisms behind apoptosis, autophagy, and ferroptosis · Bingqing Wang · 2023 · 859 citations · Cited by this paper
  20. Evaluating the efficacy of diosmetin in arthritis treatment in Albino Wistar rats · 2026 · Related
  21. Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics · Xiaoxv Dong · 2016 · 795 citations · Cited by this paper
  22. Unsolved mysteries: How does lipid peroxidation cause ferroptosis? · Huizhong Feng · 2018 · 777 citations · Cited by this paper
  23. The release and activity of HMGB1 in ferroptosis · Qirong Wen · 2019 · 676 citations · Cited by this paper
  24. Oxidative Damage and Antioxidant Defense in Ferroptosis · Feimei Kuang · 2020 · 545 citations · Cited by this paper
  25. Contribution of ferroptosis and GPX4’s dual functions to osteoarthritis progression · Miao Yu · 2022 · 507 citations · Cited by this paper
  26. Increased Reactive Oxygen Species Formation and Oxidative Stress in Rheumatoid Arthritis · Somaiya Mateen · 2016 · 439 citations · Cited by this paper
  27. Interaction between macrophages and ferroptosis · Yan Yang · 2022 · 387 citations · Cited by this paper
  28. Iron overloaded polarizes macrophage to proinflammation phenotype through ROS /acetyl‐p53 pathway · Yun Zhou · 2018 · 349 citations · Cited by this paper
  29. A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency · Haifa H. Jabara · 2015 · 294 citations · Cited by this paper
  30. TNF antagonist sensitizes synovial fibroblasts to ferroptotic cell death in collagen-induced arthritis mouse models · Jiao Wu · 2022 · 279 citations · Cited by this paper
  31. RANKL expressed on synovial fibroblasts is primarily responsible for bone erosions during joint inflammation · Lynett Danks · 2015 · 242 citations · Cited by this paper
  32. The role of iron homeostasis in remodeling immune function and regulating inflammatory disease · Qingdian Mu · 2021 · 228 citations · Cited by this paper
  33. Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells · Jefte M. Drijvers · 2020 · 190 citations · Cited by this paper
  34. Long-Term Accumulation, Biological Effects and Toxicity of BSA-Coated Gold Nanoparticles in the Mouse Liver, Spleen, and Kidneys · Kristína Jakič · 2024 · 168 citations · Cited by this paper
  35. Semaphorin 5A suppresses ferroptosis through activation of PI3K-AKT-mTOR signaling in rheumatoid arthritis · Qi Cheng · 2022 · 137 citations · Cited by this paper
  36. Icariin protects against iron overload‐induced bone loss via suppressing oxidative stress · Xingzhi Jing · 2018 · 129 citations · Cited by this paper
  37. ROS-Responsive Berberine Polymeric Micelles Effectively Suppressed the Inflammation of Rheumatoid Arthritis by Targeting Mitochondria · Xing‐Xing Fan · 2020 · 129 citations · Cited by this paper
  38. A Review of the Ethnomedicinal Uses, Biological Activities, and Triterpenoids of Euphorbia Species · Douglas Kemboi · 2020 · 126 citations · Cited by this paper
  39. Ferroptosis: a novel regulated cell death participating in cellular stress response, radiotherapy, and immunotherapy · Xiaogang Zheng · 2023 · 125 citations · Cited by this paper

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