Research map: Microbial influence on tryptophan metabolism in tumors:Mechanisms and potential clinical applications

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  1. A human gut microbial gene catalogue established by metagenomic sequencing · Junjie Qin · 2010 · 11917 citations · Cited by this paper
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  19. Kynurenine Pathway of Tryptophan Metabolism: Regulatory and Functional Aspects · Abdulla A.‐B. Badawy · 2017 · 1174 citations · Cited by this paper
  20. A highly efficient modality to block the degradation of tryptophan for cancer immunotherapy: locked nucleic acid-modified antisense oligonucleotides to inhibit human indoleamine 2,3-dioxygenase 1/tryptophan 2,3-dioxygenase expression · 2020 · Related
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  23. Indoleacrylic Acid Produced by Commensal Peptostreptococcus Species Suppresses Inflammation · Marta Wlodarska · 2017 · 899 citations · Cited by this paper
  24. Small molecules from the human microbiota · Mohamed S. Donia · 2015 · 800 citations · Cited by this paper
  25. The kynurenine pathway: a finger in every pie · Jonathan B. Savitz · 2019 · 781 citations · Cited by this paper
  26. Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity · Kebria Hezaveh · 2022 · 765 citations · Cited by this paper
  27. Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment · Mackenzie J. Bender · 2023 · 719 citations · Cited by this paper
  28. Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism · Nam Trung Nguyen · 2010 · 688 citations · Cited by this paper
  29. Indole and Tryptophan Metabolism: Endogenous and Dietary Routes to Ah Receptor Activation · Troy D. Hubbard · 2015 · 646 citations · Cited by this paper
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  31. Establishing or Exaggerating Causality for the Gut Microbiome: Lessons from Human Microbiota-Associated Rodents · Jens Walter · 2020 · 595 citations · Cited by this paper
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  33. Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks · Filipe De Vadder · 2018 · 590 citations · Cited by this paper
  34. Tryptophan metabolism, from nutrition to potential therapeutic applications · Nathalie Le Floc'H · 2010 · 576 citations · Cited by this paper
  35. Roles of Indole as an Interspecies and Interkingdom Signaling Molecule · Jin-Hyung Lee · 2015 · 534 citations · Cited by this paper
  36. Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine · Luís Felipe Campesato · 2020 · 517 citations · Cited by this paper
  37. Tryptophan Metabolism and Gut-Brain Homeostasis · William Roth · 2021 · 517 citations · Cited by this paper
  38. Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer · Joseph Tintelnot · 2023 · 485 citations · Cited by this paper
  39. IDO1 in cancer: a Gemini of immune checkpoints · Lijie Zhai · 2018 · 480 citations · Cited by this paper

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