Research map: From meal to medicine: exploring the roots and consequences of drug-food effects

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Papers in this map

  1. A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability · Gordon L. Amidon · 1995 · 5392 citations · Cited by this paper
  2. Dose optimization of omadacycline for the treatment of nontuberculous mycobacterial pulmonary disease (NTM-PD) using a physiologically based pharmacokinetic modeling approach · 2025 · Related
  3. Cholesterol-lowering effects of dietary fiber: a meta-analysis · Lisa E. Brown · 1999 · 1871 citations · Cited by this paper
  4. Architecture-driven optimization of nanocarriers for pH-responsive drug delivery · 2026 · Related
  5. Predicting Drug Disposition via Application of BCS: Transport/Absorption/ Elimination Interplay and Development of a Biopharmaceutics Drug Disposition Classification System · Chi‐Yuan Wu · 2005 · 1401 citations · Cited by this paper
  6. Antimicrobial and thermostabilizing properties of a novel surfactant on different bacterial species · 2026 · Related
  7. Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: Basic approaches and practical applications · Yohei Kawabata · 2011 · 1186 citations · Cited by this paper
  8. Mechanistic insights into the self-assembly and cellular uptake of thermoresponsive pNIPAM-grafted hyaluronic acid nanogels · 2025 · Related
  9. Dissolution Testing as a Prognostic Tool for Oral Drug Absorption: Immediate Release Dosage Forms · Jennifer Dressman · 1998 · 1088 citations · Cited by this paper
  10. Exploring anti-integrin α6 antibody and transferrin-decorated dual drug-loaded liposomes as a promising nanoplatform for glioblastoma therapy: a preclinical approach · 2025 · Related
  11. Evaluation of Various Dissolution Media for Predicting In Vivo Performance of Class I and II Drugs · Eric Galia · 1998 · 928 citations · Cited by this paper
  12. Necessity of considering sex factors in the clinical application of transdermal formulations · 2025 · Related
  13. Modern bioavailability, bioequivalence and biopharmaceutics classification system. New scientific approaches to international regulatory standards · R Löbenberg · 2000 · 730 citations · Cited by this paper
  14. Immune-chemo combination therapy using doxorubicin/viral epitope Pluronic nanoparticles · 2025 · Related
  15. Fruit juices inhibit organic anion transporting polypeptide–mediated drug uptake to decrease the oral availability of fexofenadine · George K. Dresser · 2002 · 609 citations · Cited by this paper
  16. Unveiling the treatment potential of irinotecan-loaded biopolymeric nanocarrier system in skin cancer via targeting CD44 receptors · 2025 · Related
  17. A Comparison of Physiochemical Property Profiles of Development and Marketed Oral Drugs · Mark C. Wenlock · 2003 · 546 citations · Cited by this paper
  18. Advances in pharmaceutical formulation technologies for thermostable vaccine platforms considering patient-centered design · 2025 · Related
  19. Drug, Meal and Formulation Interactions Influencing Drug Absorption After Oral Administration · David Fleisher · 1999 · 506 citations · Cited by this paper
  20. Applications of mesoporous silica particles in amorphous solid dispersion · 2025 · Related
  21. Water-soluble dietary fibers and cardiovascular disease · Elke Theuwissen · 2008 · 488 citations · Cited by this paper
  22. Physiological Parameters for Oral Delivery and in Vitro Testing · Deanna M. Mudie · 2010 · 487 citations · Cited by this paper
  23. Quantification of Gastrointestinal Liquid Volumes and Distribution Following a 240 mL Dose of Water in the Fasted State · Deanna M. Mudie · 2014 · 481 citations · Cited by this paper
  24. The Use of Biorelevant Dissolution Media to Forecast the In Vivo Performance of a Drug · Sandra Klein · 2010 · 458 citations · Cited by this paper
  25. Lipid-based delivery systems and intestinal lymphatic drug transport: A mechanistic update · Natalie L. Trevaskis · 2007 · 445 citations · Cited by this paper
  26. The mechanisms of pharmacokinetic food-drug interactions – A perspective from the UNGAP group · Mirko Koziolek · 2019 · 384 citations · Cited by this paper
  27. Effects of Food on Clinical Pharmacokinetics · Brahma Nand Singh · 1999 · 363 citations · Cited by this paper
  28. Effects of Fat on Gastric Emptying of and the Glycemic, Insulin, and Incretin Responses to a Carbohydrate Meal in Type 2 Diabetes · Diana Gentilcore · 2006 · 353 citations · Cited by this paper
  29. The Biopharmaceutics Classification System: Subclasses for in vivo predictive dissolution (IPD) methodology and IVIVC · Yasuhiro Tsume · 2014 · 350 citations · Cited by this paper
  30. Food, gastrointestinal pH, and models of oral drug absorption · Ahmad Y. Abuhelwa · 2016 · 344 citations · Cited by this paper
  31. Effect of food on the relative bioavailability of two oral formulations of posaconazole in healthy adults · Rachel Courtney · 2003 · 327 citations · Cited by this paper
  32. Bile Acids and Their Derivatives as Potential Modifiers of Drug Release and Pharmacokinetic Profiles · Nebojša Pavlović · 2018 · 307 citations · Cited by this paper
  33. Intestinal lymphatic transport for drug delivery · Jaime A. Yáñez · 2011 · 283 citations · Cited by this paper
  34. The Effects of Food on the Dissolution of Poorly Soluble Drugs in Human and in Model Small Intestinal Fluids · Eva M. Persson · 2005 · 266 citations · Cited by this paper
  35. Gastric Response to Increased Meal Viscosity Assessed by Echo-Planar Magnetic Resonance Imaging in Humans · Luca Marciani · 2000 · 265 citations · Cited by this paper
  36. Viscosity of Oat Bran-Enriched Beverages Influences Gastrointestinal Hormonal Responses in Healthy Humans · Kristiina R. Juvonen · 2009 · 265 citations · Cited by this paper
  37. Intestinal Permeability and Drug Absorption: Predictive Experimental, Computational and In Vivo Approaches · David Dahlgren · 2019 · 257 citations · Cited by this paper
  38. Substance Use Following Bariatric Weight Loss Surgery · Alexis Conason · 2012 · 250 citations · Cited by this paper
  39. Recent Advances in Development and Application of Physiologically-Based Pharmacokinetic (PBPK) Models: a Transition from Academic Curiosity to Regulatory Acceptance · Masoud Jamei · 2016 · 245 citations · Cited by this paper

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