Research map: Life's Essential 8: Essential for Brain and Cognitive Health

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  1. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission · Gill Livingston · 2025 · 10712 citations · Cited by this paper
  2. Remnant Cholesterol Paradox: Higher Levels Are Associated With Reduced Mortality in Critically Ill Patients With Heart Failure · 2026 · Related
  3. The Physical Activity Guidelines for Americans · Katrina L. Piercy · 2018 · 9866 citations · Cited by this paper
  4. Cardiovascular Multimorbidity and Associated Mortality Among Medicare Beneficiaries Dually Eligible for Medicaid · 2026 · Related
  5. Life’s Essential 8: Updating and Enhancing the American Heart Association’s Construct of Cardiovascular Health: A Presidential Advisory From the American Heart Association · Donald M. Lloyd‐Jones · 2022 · 2785 citations · Cited by this paper
  6. Association of Weighted Composite Score of Long‐Term Variability of Vascular Risk Factors From Childhood With Midlife Cognitive Function: The Bogalusa Heart Study · 2026 · Related
  7. 2020 Alzheimer's disease facts and figures · 2020 · 2400 citations · Cited by this paper
  8. Hypothermia and Stem Cells Confer Limited Protection to Mammillary Bodies in a Neonatal Mouse Model of Hypoxia‐Ischemia · 2026 · Related
  9. Socioeconomic inequalities and mental health problems in children and adolescents: A systematic review · Franziska Reiß · 2013 · 2121 citations · Cited by this paper
  10. Association of Genetic Variants With Rivaroxaban Pharmacokinetics and Pharmacodynamics in Older Patients With Atrial Fibrillation: A Prospective Cohort Study · 2026 · Related
  11. Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population‐based perspective · Matthew Baumgart · 2015 · 1699 citations · Cited by this paper
  12. Multi‐Omics Analysis for Pathogenesis and Candidate Therapeutic Target in Thoracic Aortic Aneurysms · 2026 · Related
  13. Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults · Marco Pahor · 2014 · 1449 citations · Cited by this paper
  14. Impaired Microvascular Reactivity to Passive Limb Movement After Stroke Is Improved by a Single Session of Ischemic Conditioning · 2026 · Related
  15. Effects of sleep deprivation on cognition · William D. S. Killgore · 2010 · 1425 citations · Cited by this paper
  16. Role of Lipin‐1 in Macrophage‐Mediated Atherosclerosis: Is It Atherogenic or Atheroprotective? · 2026 · Related
  17. Population estimate of people with clinical Alzheimer's disease and mild cognitive impairment in the United States (2020–2060) · Kumar Bharat Rajan · 2021 · 1305 citations · Cited by this paper
  18. Functional Status Indicators and Long‐Term Mortality Following Elective Coronary Artery Bypass Grafting: A Multicenter Cohort Study · 2026 · Related
  19. Psychological Stress and Cardiovascular Disease · Joel E. Dimsdale · 2008 · 1129 citations · Cited by this paper
  20. Accuracy of the Clinical Diagnosis of Alzheimer Disease at National Institute on Aging Alzheimer Disease Centers, 2005–2010 · Thomas G. Beach · 2012 · 1124 citations · Cited by this paper
  21. B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review · David Opare KENNEDY · 2016 · 1047 citations · Cited by this paper
  22. Effects of Physical Exercise on Cognitive Functioning and Wellbeing: Biological and Psychological Benefits · Laura Mandolesi · 2018 · 1047 citations · Cited by this paper
  23. Does physical activity prevent cognitive decline and dementia?: A systematic review and meta-analysis of longitudinal studies · Sarah J. Blondell · 2014 · 958 citations · Cited by this paper
  24. Smoking as a Risk Factor for Dementia and Cognitive Decline: A Meta-Analysis of Prospective Studies · Kaarin Jane Anstey · 2007 · 927 citations · Cited by this paper
  25. The Prevention of Dementia With Antihypertensive Treatment New Evidence From the Systolic Hypertension in Europe (Syst-Eur) Study · Françoise Forette · 2002 · 896 citations · Cited by this paper
  26. Social Determinants of Cardiovascular Disease · Tiffany M. Powell-Wiley · 2022 · 847 citations · Cited by this paper
  27. The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans · Jerrah K. Holth · 2019 · 837 citations · Cited by this paper
  28. Obesity and neuroinflammation: A pathway to cognitive impairment · Alyson A. Miller · 2014 · 809 citations · Cited by this paper
  29. Post-Stroke Cognitive Impairment and Dementia · Natalia S. Rost · 2022 · 797 citations · Cited by this paper
  30. Aggregation of vascular risk factors and risk of incident Alzheimer disease · Jose Alejandro Luchsinger · 2005 · 793 citations · Cited by this paper
  31. The overlap between vascular disease and Alzheimer’s disease - lessons from pathology · Johannes Attems · 2014 · 750 citations · Cited by this paper
  32. The Effects of Type 1 Diabetes on Cognitive Performance · Augustina M.A. Brands · 2005 · 739 citations · Cited by this paper
  33. Epidemiologic studies of modifiable factors associated with cognition and dementia: systematic review and meta-analysis · May A. Beydoun · 2014 · 687 citations · Cited by this paper
  34. Lifestyle modification approaches for the treatment of obesity in adults. · Thomas A. Wadden · 2020 · 669 citations · Cited by this paper
  35. Meta-analysis of the acute effects of nicotine and smoking on human performance · Stephen J. Heishman · 2010 · 654 citations · Cited by this paper
  36. Relation of cerebral vessel disease to Alzheimer's disease dementia and cognitive function in elderly people: a cross-sectional study · Zoe Arvanitakis · 2016 · 605 citations · Cited by this paper
  37. The Effects of Tobacco Smoke and Nicotine on Cognition and the Brain · Gary E. Swan · 2007 · 590 citations · Cited by this paper
  38. Effects of intensive glucose lowering on brain structure and function in people with type 2 diabetes (ACCORD MIND): a randomised open-label substudy · Lenore J. Launer · 2011 · 572 citations · Cited by this paper
  39. Hypertension-induced cognitive impairment: from pathophysiology to public health · Zoltan I. Ungvari · 2021 · 565 citations · Cited by this paper

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