Research map: CTSB-Associated Inflammation and Macrophage Interaction in Heart Failure Following Myocardial Infarction and Potential Therapeutic Implications of Quercetin

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  1. Macrophage MicroRNA-155 Promotes Cardiac Hypertrophy and Failure · Stephane R B Heymans · 2013 · 241 citations · Cited by this paper
  2. Characteristics Three waves of pyripyropene fungal alkaloids and synthetic derivatives targeting ACAT2 as insecticides, anti-atherosclerosis and anticancer agents. · 2026 · Related
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  4. Low-molecular-weight fucoidan inhibits HMGB1-induced thromboinflammation by modulating HMGB1-TLR4 axis · 2026 · Related
  5. Macrophage-Derived Exosomal Mir-155 Regulating Cardiomyocyte Pyroptosis and Hypertrophy in Uremic Cardiomyopathy · Bin Wang · 2020 · 94 citations · Cited by this paper
  6. Poly(I:C) and QS-21 combination suppresses breast tumor growth and metastasis by repolarizing tumor associated macrophages to anti-tumor macrophages · 2026 · Related
  7. Effects of quercetin supplementation on inflammatory factors and quality of life in post‐myocardial infarction patients: A double blind, placebo‐controlled, randomized clinical trial · Fereshteh Dehghani · 2020 · 84 citations · Cited by this paper
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  9. Apigenin Alleviated High-Fat-Diet-Induced Hepatic Pyroptosis by Mitophagy-ROS-CTSB-NLRP3 Pathway in Mice and AML12 Cells · Zhuoqun Meng · 2023 · 84 citations · Cited by this paper
  10. PGC-1α mediates ER stress–driven apoptotic signaling during gemfibrozil treatment in glioblastoma · 2026 · Related
  11. CST6 protein and peptides inhibit breast cancer bone metastasis by suppressing CTSB activity and osteoclastogenesis · Xiaoxun Li · 2021 · 73 citations · Cited by this paper
  12. S14G-humanin (HNG) ameliorates diabetic nephropathy tubular injury by inhibiting Z-DNA/ZBP1-mediated necroptosis · 2026 · Related
  13. Hypoxia Induces M2 Macrophages to Express VSIG4 and Mediate Cardiac Fibrosis After Myocardial Infarction · Yan Wang · 2023 · 71 citations · Cited by this paper
  14. Induction and Propagation of Ferroptosis Evasion by FTH1P7 Drives Sorafenib Resistance in Hepatocellular Carcinoma · 2026 · Related
  15. CTSB promotes sepsis-induced acute kidney injury through activating mitochondrial apoptosis pathway · Yuting Wang · 2023 · 62 citations · Cited by this paper
  16. A functional coupling of TRPA1 and TMEM16A channels regulates endothelium-dependent hyperpolarization-mediated vasorelaxation of mesenteric resistance arteries in healthy and septic mice · 2026 · Related
  17. Effect of Neprilysin Inhibition on Left Ventricular Remodeling in Patients With Asymptomatic Left Ventricular Systolic Dysfunction Late After Myocardial Infarction · Kieran F. Docherty · 2021 · 54 citations · Cited by this paper
  18. Role of Abca7-related microglial responses in linking type 2 diabetes mellitus to Alzheimer's disease progression: Evidence from single-cell transcriptomic analysis and experimental validation in animal and cell models · 2026 · Related
  19. Quercitrin improves cardiac remodeling following myocardial infarction by regulating macrophage polarization and metabolic reprogramming · Congyong Liu · 2024 · 50 citations · Cited by this paper
  20. Pulmonary fibrosis and the TGF-β signaling axis: Advances in targeted therapeutics · 2026 · Related
  21. Pepducin-mediated cardioprotection via β-arrestin-biased β2-adrenergic receptor-specific signaling · Laurel A. Grisanti · 2018 · 49 citations · Cited by this paper
  22. Extracellular Matrix Protein-1 as a Mediator of Inflammation-Induced Fibrosis After Myocardial Infarction · Sean A. Hardy · 2023 · 29 citations · Cited by this paper
  23. Tissue factor cytoplasmic domain exacerbates post-infarct left ventricular remodeling via orchestrating cardiac inflammation and angiogenesis · Suet Yen Chong · 2021 · 26 citations · Cited by this paper
  24. The Role of Epicardial Adipose Tissue in Acute Coronary Syndromes, Post-Infarct Remodeling and Cardiac Regeneration · Kamil Krauz · 2024 · 23 citations · Cited by this paper
  25. Independent roles of CGRP in cardioprotection and hemodynamic regulation in ischemic postconditioning · Zheng Guo · 2018 · 21 citations · Cited by this paper
  26. Therapeutic S100A8/A9 inhibition reduces NADPH oxidase expression, reactive oxygen species production and NLRP3 inflammasome priming in the ischemic myocardium · Mihaela-Loredana Vlad · 2025 · 20 citations · Cited by this paper
  27. Impact of quercetin in patients with myocardial infarction. A multicenter, randomized, and open-label pilot study · Sergey Kozhukhov · 2023 · 17 citations · Cited by this paper
  28. Role of Aldosterone in Mid- and Long-Term Left Ventricular Remodelling after Acute Myocardial Infarction: The REMI Study · Luca Monzo · 2023 · 14 citations · Cited by this paper
  29. Features of metabolic syndrome and inflammation independently affect left ventricular function early after first myocardial infarction · Jan Traub · 2022 · 13 citations · Cited by this paper
  30. Biologically derived epicardial patch induces macrophage mediated pathophysiologic repair in chronically infarcted swine hearts · Jordan J. Lancaster · 2023 · 9 citations · Cited by this paper
  31. Persistent Ferroptosis Modulates Cardiac Remodeling and M2 Macrophage Polarization, Which Can be Mitigated by Astaxanthin During Myocardial Infarction Recovery · Cheng Shen · 2024 · 9 citations · Cited by this paper
  32. Long-term transcranial ultrasound stimulation regulates neuroinflammation to ameliorate post–myocardial infarction cardiac arrhythmia and remodeling · Haoyuan Hu · 2024 · 6 citations · Cited by this paper
  33. Efficacy and safety of empagliflozin for the acute myocardial infarction: a systematic review and meta-analysis of randomized controlled trials · Lei Peng · 2025 · 6 citations · Cited by this paper
  34. Shikonin from lithospermum erythrorhizon induces pyroptosis in trophoblast cells by activating the CTSB-NLRP3 inflammasome · Fuling Zeng · 2024 · 5 citations · Cited by this paper
  35. Left ventricular flow kinetics and myocardial deformation following acute infarction: Additional predictive value of cardiac magnetic resonance four-dimensional flow for left ventricular remodeling post-ST-elevation myocardial infarction · Christel H. Kamani · 2025 · 5 citations · Cited by this paper
  36. Antagonizing CCR2 With Propagermanium Leads to Altered Distribution of Macrophage Subsets and Favorable Tissue Remodeling After Myocardial Infarction in Mice · Kay F. Weipert · 2025 · 5 citations · Cited by this paper
  37. Targeting Inflammation with Galectin-3 and PIIINP Modulation Among ST-Segment Elevation Acute Coronary Syndrome Patients Underwent Delayed Percutaneous Coronary Intervention · Saskia Dyah Handari · 2025 · 4 citations · Cited by this paper
  38. Endothelial progenitor cells have high predictive value for ventricular remodeling after percutaneous coronary intervention in acute myocardial infarction · Yongxiang Ma · 2024 · 2 citations · Cited by this paper
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