Research map: Tnxb Alleviates Myocardial Ischemia-Reperfusion Injury Through Facilitating Akt-Dependent Endothelial Cell Survival and Angiogenesis in Mice

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  1. Signaling pathways and targeted therapy for myocardial infarction · Qing Zhang · 2022 · 856 citations · Cited by this paper
  2. Non-canonical PPARα Agonism by Arjunolic Acid Mitigates Cardiomyocyte PANoptosis Through a Novel PPARα/CRYAB/IKKα Axis During Pathological Cardiac Hypertrophy · 2026 · Related
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  9. KLF2 and KLF4 control endothelial identity and vascular integrity · Panjamaporn Sangwung · 2017 · 260 citations · Cited by this paper
  10. GLI1 Promotes Hypoxia Induced Pyroptosis of PASMCs and Aggravates Pulmonary Arterial Hypertension in Rats by Upregulating HDAC1 Expression · 2026 · Related
  11. The role of PI3K/AKT signaling pathway in myocardial ischemia-reperfusion injury · Rui-ming Deng · 2023 · 194 citations · Cited by this paper
  12. E-cigarette Aerosol Containing Nicotine Increases Aortic Stiffness in Young Mice · 2026 · Related
  13. STING aggravates ferroptosis-dependent myocardial ischemia-reperfusion injury by targeting GPX4 for autophagic degradation · Xiaohong Wang · 2025 · 152 citations · Cited by this paper
  14. Microplastics and Nanoplastics in Cardiovascular Disease: An Emerging Cardiovascular Risk Factor · 2026 · Related
  15. Inflammation in Myocardial Ischemia/Reperfusion Injury: Underlying Mechanisms and Therapeutic Potential · Jamie J Francisco · 2023 · 147 citations · Cited by this paper
  16. Pioglitazone Mitigates Arsenic-Induced Cardiotoxicity via Lipid Metabolism: Network Pharmacology and Molecular Docking Approach · 2026 · Related
  17. The pathological mechanisms and potential therapeutic drugs for myocardial ischemia reperfusion injury · Shuo Zhang · 2024 · 143 citations · Cited by this paper
  18. Role of l-Arginine and Tetrahydrobiopterin in Attenuation of Vascular Ang1-8 Reactivity via Endothelial PI3K/AKT/eNOS Signaling Pathways in HgCl2-Induced Vascular Dysfunction. An Ex-Vivo Study · 2026 · Related
  19. Transcriptional regulation of tenascin genes · Francesca Chiovaro · 2015 · 131 citations · Cited by this paper
  20. SETD2 Improves Endothelial Function and Angiogenesis in Diabetic Hindlimb Ischemia Via Activating ANGPT2-PI3K/AKT Pathway · 2026 · Related
  21. Tenascin-X Mediates Flow-Induced Suppression of EndMT and Atherosclerosis · Guozheng Liang · 2022 · 110 citations · Cited by this paper
  22. The E3 ubiquitin ligase MARCH2 protects against myocardial ischemia-reperfusion injury through inhibiting pyroptosis via negative regulation of PGAM5/MAVS/NLRP3 axis · Shuolin Liu · 2024 · 105 citations · Cited by this paper
  23. Pleiotropic effects of laminar flow and statins depend on the Krüppel-like factor-induced lncRNA MANTIS · Matthias S. Leisegang · 2019 · 83 citations · Cited by this paper
  24. KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress · Jan-Renier A. J. Moonen · 2022 · 79 citations · Cited by this paper
  25. Myocardial Ischemia–Reperfusion Injury: Unraveling Pathophysiology, Clinical Manifestations, and Emerging Prevention Strategies · Μarios Sagris · 2024 · 71 citations · Cited by this paper
  26. A detrimental role of endothelial S1PR2 in cardiac ischemia-reperfusion injury via modulating mitochondrial dysfunction, NLRP3 inflammasome activation, and pyroptosis · Yunhao Duan · 2024 · 63 citations · Cited by this paper
  27. Bone Marrow Mesenchymal Stem Cell-Derived Exosomal KLF4 Alleviated Ischemic Stroke Through Inhibiting N6-Methyladenosine Modification Level of Drp1 by Targeting lncRNA-ZFAS1 · Qingsong Wang · 2023 · 57 citations · Cited by this paper
  28. Mechanisms of postischemic cardiac death and protection following myocardial injury · Yusuf Mastoor · 2025 · 53 citations · Cited by this paper
  29. Vascular endothelial cell injury: causes, molecular mechanisms, and treatments · Tian Xia · 2025 · 46 citations · Cited by this paper
  30. Mitochondrial apoptosis in response to cardiac ischemia-reperfusion injury · Kaixin Wang · 2025 · 43 citations · Cited by this paper
  31. A review of KLF4 and inflammatory disease: Current status and future perspective · Yidan Liang · 2024 · 39 citations · Cited by this paper
  32. Platelet Membrane‐Fused Circulating Extracellular Vesicles Protect the Heart from Ischemia/Reperfusion Injury · Jizong Jiang · 2023 · 33 citations · Cited by this paper
  33. (‑)‑Epicatechin protects against myocardial ischemia‑induced cardiac injury via activation of the PTEN/PI3K/AKT pathway · Jiawen Li · 2018 · 32 citations · Cited by this paper
  34. SWI/SNF-dependent genes are defined by their chromatin landscape · Laura Basurto-Cayuela · 2024 · 31 citations · Cited by this paper
  35. Endothelial γ-protocadherins inhibit KLF2 and KLF4 to promote atherosclerosis · Divyesh Joshi · 2024 · 30 citations · Cited by this paper
  36. Targeting the Endothelium to Achieve Cardioprotection · Nicolas Herrera-Zelada · 2021 · 28 citations · Cited by this paper
  37. Deletion of Extra Domain A of Fibronectin Reduces Acute Myocardial Ischaemia/Reperfusion Injury in Hyperlipidaemic Mice by Limiting Thrombo-Inflammation · Mehul R. Chorawala · 2018 · 27 citations · Cited by this paper
  38. Tenascin-X—Discovery and Early Research · Walter L. Miller · 2021 · 27 citations · Cited by this paper
  39. Klf4 deficiency exacerbates myocardial ischemia/reperfusion injury in mice via enhancing ROCK1/DRP1 pathway-dependent mitochondrial fission · Yueyang Li · 2022 · 26 citations · Cited by this paper

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