Research map: Volumetric Absorptive Microsampling During Spaceflight for Analysis of Acetaminophen Pharmacokinetics in Whole Blood

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  1. Metabolism and Disposition of Acetaminophen: Recent Advances in Relation to Hepatotoxicity and Diagnosis · Mitchell R. McGill · 2013 · 709 citations · Cited by this paper
  2. Comment on “Understanding Atomoxetine Exposure Variability in Children and Adolescents with ADHD through Population Pharmacokinetics” · 2026 · Related
  3. Clinical Pharmacokinetics of Paracetamol · John A. H. Forrest · 1982 · 494 citations · Cited by this paper
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  5. Distribution, function and physiological role of melatonin in the lower gut · Chunqiu Chen · 2011 · 258 citations · Cited by this paper
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  7. The Effect of Hematocrit on Bioanalysis of DBS: Results from The EBF DBS-Microsampling Consortium · Ronald de Vries · 2013 · 136 citations · Cited by this paper
  8. Population Pharmacokinetic Modeling of Intravenous Topiramate in Patients with Epilepsy or Migraine · 2026 · Related
  9. Medication use by U.S. crewmembers on the International Space Station · Virginia E. Wotring · 2015 · 121 citations · Cited by this paper
  10. Decoupling CAR‐T Expansion, Conversion, and Decay Timing: Physiologically Aligned Semi‐Mechanistic Modeling With Smooth Gating and a Cauchy Likelihood Residual Model · 2026 · Related
  11. Alterations in hematologic indices during long-duration spaceflight · Hawley Kunz · 2017 · 85 citations · Cited by this paper
  12. Hepatic CYP1A2 Activity in Adolescents with and without Obesity Assessed by the Urinary Paraxanthine‐to‐Caffeine Metabolic Ratio: A Pharmacokinetic Study · 2026 · Related
  13. Plasma and Blood Volume in Space · André Diedrich · 2007 · 74 citations · Cited by this paper
  14. Pharmacokinetics, Safety, and Tolerability of Anti‐miR‐17 Oligonucleotide RGLS4326 in Healthy Adult Subjects · 2026 · Related
  15. Quantitative bioanalysis of paracetamol in rats using volumetric absorptive microsampling (VAMS) · Philip Denniff · 2015 · 73 citations · Cited by this paper
  16. Population Pharmacokinetics and Exposure‐Safety Analysis of Furosemide in Preterm Infants · 2026 · Related
  17. Altered carbohydrate, lipid, and xenobiotic metabolism by liver from rats flown on Cosmos 1887 · Alfred H. Merrill · 1990 · 59 citations · Cited by this paper
  18. Population Pharmacokinetics of Oral Gecacitinib in Healthy Subjects and Patients with Autoimmune and Inflammatory Diseases · 2026 · Related
  19. A comparative study of saliva and serum paracetamol levels using a simple spectrophotometric method. · C. Adithan · 1982 · 51 citations · Cited by this paper
  20. Street Pharmacology: The Mechanistic Basis of Clinical Pharmacology Underlying the Microdosing Method of Buprenorphine–Naloxone With a Focus on the Unhoused Population · 2026 · Related
  21. The pharmacokinetic profile of a novel fixed-dose combination tablet of ibuprofen and paracetamol · T. Tanner · 2010 · 50 citations · Cited by this paper
  22. Influence of posture on pharmacokinetics · Christian Queckenberg · 2008 · 50 citations · Cited by this paper
  23. Influence of Simulated Weightlessness on the Oral Pharmacokinetics of Acetaminophen as a Gastric Emptying Probe in Man: A Plasma and a Saliva Study · Peggy Gandia · 2003 · 48 citations · Cited by this paper
  24. The influence of posture on the pharmacokinetics of orally administered nifedipine. · AG Renwick · 1992 · 47 citations · Cited by this paper
  25. Collection of biospecimens from the inspiration4 mission establishes the standards for the space omics and medical atlas (SOMA) · Eliah G. Overbey · 2024 · 45 citations · Cited by this paper
  26. Ibuprofen and acetaminophen kinetics when taken concurrently · Caroline E. Wright · 1983 · 44 citations · Cited by this paper
  27. Spaceflight Effects on Cytochrome P450 Content in Mouse Liver · Natalia E. Moskaleva · 2015 · 43 citations · Cited by this paper
  28. Physiological adaptations affecting drug pharmacokinetics in space: what do we really know? A critical review of the literature · Cinzia Dello Russo · 2022 · 42 citations · Cited by this paper
  29. Pharmacokinetics of acetaminophen administered in tablets and capsules under long-term space flight conditions · Irina V. Kovachevich · 2009 · 41 citations · Cited by this paper
  30. Effects of Posture and Sleep on the Pharmacokinetics of Paracetamol (Acetaminophen) and Its Metabolites · Roger H. Rumble · 1991 · 36 citations · Cited by this paper
  31. Volumetric Absorptive Microsampling in Therapeutic Drug Monitoring of Immunosuppressive Drugs—From Sampling and Analytical Issues to Clinical Application · Arkadiusz Kocur · 2022 · 35 citations · Cited by this paper
  32. Effect of posture and sleep on pharmacokinetics · Michael Stephen Roberts · 1980 · 33 citations · Cited by this paper
  33. How do the pharmacokinetics of drugs change in astronauts in space? · Sara Eyal · 2020 · 33 citations · Cited by this paper
  34. Pharmacokinetic Consequences of Spaceflight · Lakshmi Putcha · 1991 · 30 citations · Cited by this paper
  35. Volumetric absorptive microsampling as an alternative sampling strategy for the determination of paracetamol in blood and cerebrospinal fluid · Lisa Delahaye · 2018 · 24 citations · Cited by this paper
  36. Determination of paracetamol and its metabolites via LC-MS/MS in dried blood volumetric absorptive microsamples: A tool for pharmacokinetic studies · Lisa Delahaye · 2021 · 22 citations · Cited by this paper
  37. Infections in long-duration space missions · Daniel Cowen · 2024 · 19 citations · Cited by this paper
  38. Effect of dehydration on blood tests · Muhammad Masood Ashraf · 2017 · 17 citations · Cited by this paper
  39. Influence of simulated weightlessness on the pharmacokinetics of acetaminophen administered by the oral route: a study in the rat · Peggy Gandia · 2004 · 16 citations · Cited by this paper

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