Research map: Cancer Neuroscience of Kinase Inhibitors: On-Target Effects on the Nervous System

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  1. Neurotrophin-regulated signalling pathways · Louis French Reichardt · 2006 · 2217 citations · Cited by this paper
  2. Neural Correlates of Diagnostic-Relevant Emotional Processing in Schizophrenia and Major Depressive Disorder: Insights from a Replication of fMRI and Self-Report Scales · 2026 · Related
  3. NTRK fusion-positive cancers and TRK inhibitor therapy · Emiliano Cocco · 2018 · 1508 citations · Cited by this paper
  4. Long-Term Orchestral String Learning and Event-Related Potentials of Inhibitory Control in Children From Disadvantaged Communities · 2026 · Related
  5. Bevacizumab (Avastin®) in cancer treatment: A review of 15 years of clinical experience and future outlook · Josep Garcia · 2020 · 1183 citations · Cited by this paper
  6. Dl-3-n-Butylphthalide Protects Human Brain Microvascular Endothelial Cells Against Ischemic Injury Through Dual Modulation of HIF1α/VEGF-Mediated Angiogenesis and COX2-Mediated Inflammation · 2026 · Related
  7. MAP kinase and pain · Ru‐Rong Ji · 2008 · 994 citations · Cited by this paper
  8. Molecular Mechanisms and Potential Biomarkers of Neuropsychiatric Disorders in Parkinson’s Disease · 2026 · Related
  9. Trends in kinase drug discovery: targets, indications and inhibitor design · Misty M. Attwood · 2021 · 817 citations · Cited by this paper
  10. Extracellular Vesicle-Mediated Delivery of VEGF and NGF Protects Dopaminergic Neurons in 6-OHDA-Induced Parkinson’s Disease Models · 2026 · Related
  11. Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements · Rüdiger Klein · 1994 · 631 citations · Cited by this paper
  12. Glymphatic-Related Alterations in Major Depressive Disorder and Treatment-Resistant Depression: Imaging Proxies, Mechanistic Links, and Therapeutic Opportunities · 2026 · Related
  13. Cancer neuroscience: State of the field, emerging directions · Frank Winkler · 2023 · 555 citations · Cited by this paper
  14. Atractylodin Suppresses Fibrotic Scar Formation and Enhances Functional Recovery Following Spinal Cord Injury · 2026 · Related
  15. Trk receptor tyrosine kinases: A bridge between cancer and neural development · Akira Nakagawara · 2001 · 498 citations · Cited by this paper
  16. A Capacitance-Based System for Measuring Licking Behaviour in Rodents With Sub-Second Precision · 2026 · Related
  17. RET tyrosine kinase signaling in development and cancer · Elena Arighi · 2005 · 471 citations · Cited by this paper
  18. Single-Cell and Integrative Analyses Uncover Therapeutic Potential of RFX1-Mediated Cuproptosis in PitNETs · 2026 · Related
  19. Pralsetinib for RET fusion-positive non-small-cell lung cancer (ARROW): a multi-cohort, open-label, phase 1/2 study · Justin F. Gainor · 2021 · 456 citations · Cited by this paper
  20. Functional Diversity of Mouse dLGN Neurons and Modulation of Their Encoding Properties by Superior Colliculus · 2026 · Related
  21. Anaplastic lymphoma kinase: signalling in development and disease · Ruth Helen Palmer · 2009 · 425 citations · Cited by this paper
  22. Properties of FDA-approved small molecule protein kinase inhibitors: A 2024 update · Robert Jr. Roskoski · 2024 · 391 citations · Cited by this paper
  23. MAPK activation in nociceptive neurons and pain hypersensitivity · Koichi Obata · 2004 · 361 citations · Cited by this paper
  24. Functionalized Nanomaterials Capable of Crossing the Blood–Brain Barrier · Shuai Zha · 2024 · 359 citations · Cited by this paper
  25. EML4-ALK Rearrangement in Non-Small Cell Lung Cancer and Non-Tumor Lung Tissues · Maria Paola Martelli · 2009 · 322 citations · Cited by this paper
  26. Ponsegromab for the Treatment of Cancer Cachexia · John D. Groarke · 2024 · 307 citations · Cited by this paper
  27. Targeting TRK family proteins in cancer · Yekaterina B. Khotskaya · 2017 · 302 citations · Cited by this paper
  28. EGFR family: Structure physiology signalling and therapeutic targets † · Antony Wilks Burgess · 2008 · 293 citations · Cited by this paper
  29. Targeting EGFR and VEGF(R) pathway cross-talk in tumor survival and angiogenesis · Annette Kragh Larsen · 2011 · 269 citations · Cited by this paper
  30. Repotrectinib in ROS1 Fusion–Positive Non–Small-Cell Lung Cancer · Alexander Edward Dela Cruz Drilon · 2024 · 236 citations · Cited by this paper
  31. Neurotrophic factor control of satiety and body weight · Baoji Xu · 2016 · 210 citations · Cited by this paper
  32. Neurotrophins and Neuropathic Pain: Role in Pathobiology · Nemat Khan · 2015 · 204 citations · Cited by this paper
  33. Insights Into Mechanisms of GDF15 and Receptor GFRAL: Therapeutic Targets · Luc Rochette · 2020 · 190 citations · Cited by this paper
  34. Molecular basis of congenital insensitivity to pain with anhidrosis (CIPA): Mutations and polymorphisms inTRKA (NTRK1) gene encoding the receptor tyrosine kinase for nerve growth factor · Yasuhiro Indo · 2001 · 189 citations · Cited by this paper
  35. Precision therapy for RET-altered cancers with RET inhibitors · Kyaw Zin Thein · 2021 · 178 citations · Cited by this paper
  36. A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain · Deepitha Selvaraj · 2015 · 169 citations · Cited by this paper
  37. NGF /TrkA Signaling as a Therapeutic Target for Pain · Munetaka Hirose · 2015 · 142 citations · Cited by this paper
  38. Activated EGFR signaling increases proliferation, survival, and migration and blocks neuronal differentiation in post-natal neural stem cells · Ángel Ayuso‐Sacido · 2009 · 125 citations · Cited by this paper
  39. Anti–Vascular Endothelial Growth Factor Therapies as a Novel Therapeutic Approach to Treating Neurofibromatosis-Related Tumors · Hon Kit Wong · 2010 · 121 citations · Cited by this paper

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