Research map: Mechanobiological Dysregulation of Fibroblasts and Extracellular Matrix Failure in Pelvic Organ Prolapse

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  1. Remodelling the extracellular matrix in development and disease · Caroline Bonnans · 2014 · 4502 citations · Cited by this paper
  2. Global Landscape and Translational Trajectories of Pelvic Floor Muscle Rehabilitation for Urinary Incontinence · 2026 · Related
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  5. Extracellular Matrix Degradation and Remodeling in Development and Disease · Pengfei Lu · 2011 · 2327 citations · Cited by this paper
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  7. Mechanotransduction and extracellular matrix homeostasis · Jay D. Humphrey · 2014 · 2226 citations · Cited by this paper
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  11. Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus · Ning Wang · 2008 · 1791 citations · Cited by this paper
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  13. Generic Diagramming Platform (GDP): a comprehensive database of high-quality biomedical graphics · Shuai Jiang · 2024 · 1638 citations · Cited by this paper
  14. Are We Missing the Bladder? Reflections on Endometriosis and IC/BPS · 2026 · Related
  15. Fibroblasts: Origins, definitions, and functions in health and disease · Maksim V. Plikus · 2021 · 1187 citations · Cited by this paper
  16. Can ChatGPT Be Trusted for Urologic Patient Education? A Comparative Study of Stress Urinary Incontinence-Related Information From Versions 3.5 and 4 · 2026 · Related
  17. Fibroblasts and myofibroblasts in wound healing · Alexis Desmoulière · 2014 · 1049 citations · Cited by this paper
  18. Beyond the Apnea–Hypopnea Index: Circadian–Autonomic and Natriuretic Pathways in the Association Between Obstructive Sleep Apnea and Overactive Bladder · 2026 · Related
  19. Cellular Mechanotransduction: From Tension to Function · Fabiana De Martino · 2018 · 1020 citations · Cited by this paper
  20. Effect of Vaginal Palpation on Voluntary Pelvic Floor Muscle Performance During Early Motor Learning in Women with Stress Urinary Incontinence (SUI): A Randomized Controlled Trial · 2026 · Related
  21. Cell–matrix adhesion · Allison L. Berrier · 2007 · 962 citations · Cited by this paper
  22. Pelvic organ prolapse · John Eric Jelovsek · 2007 · 946 citations · Cited by this paper
  23. The Actin Cytoskeleton and Actin-Based Motility · Tatyana Svitkina · 2018 · 814 citations · Cited by this paper
  24. Wound healing, fibroblast heterogeneity, and fibrosis · Heather E. Talbott · 2022 · 801 citations · Cited by this paper
  25. YAP regulates cell mechanics by controlling focal adhesion assembly · Giorgia Nardone · 2017 · 692 citations · Cited by this paper
  26. Fibroblast and myofibroblast activation in normal tissue repair and fibrosis · Fereshteh Sadat Younesi · 2024 · 672 citations · Cited by this paper
  27. Functional Anatomy of the Female Pelvic Floor · James A. Ashton‐Miller · 2007 · 572 citations · Cited by this paper
  28. The mechanical memory of lung myofibroblasts · Jenna Leigh Balestrini · 2012 · 393 citations · Cited by this paper
  29. Myofibroblasts in human granulation tissue · Graeme B. Ryan · 1974 · 390 citations · Cited by this paper
  30. Mechanisms of assembly and remodelling of the extracellular matrix · Alexandra Naba · 2024 · 314 citations · Cited by this paper
  31. The relationship of vaginal prolapse severity tosymptoms and quality of life · Giuseppe Alessandro Digesu · 2005 · 256 citations · Cited by this paper
  32. The Role of Myofibroblasts in Physiological and Pathological Tissue Repair · Ronen Schuster · 2022 · 231 citations · Cited by this paper
  33. Mechanical regulation of myofibroblast phenoconversion and collagen contraction · Boris Hinz · 2019 · 183 citations · Cited by this paper
  34. Failure of Elastic Fiber Homeostasis Leads to Pelvic Floor Disorders · Xiaoqing Liu · 2006 · 171 citations · Cited by this paper
  35. Alterations in Connective Tissue Metabolism in Stress Incontinence and Prolapse · Bertha H. Chen · 2011 · 146 citations · Cited by this paper
  36. Collagen changes in pelvic support tissues in women with pelvic organ prolapse · Runqi Gong · 2019 · 107 citations · Cited by this paper
  37. Role of Fibroblasts and Myofibroblasts on the Pathogenesis and Treatment of Pelvic Organ Prolapse · Zeliha Güler · 2022 · 107 citations · Cited by this paper
  38. Collagen content of nonsupport tissue in pelvic organ prolapse and stress urinary incontinence · Michael Y.C. Wong · 2003 · 98 citations · Cited by this paper
  39. Single-cell transcriptome profiling of the vaginal wall in women with severe anterior vaginal prolapse · Yaqian Li · 2021 · 95 citations · Cited by this paper

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