Research map: Molecular mechanism of lead exposure induced atrial fibrillation: A systematic study based on network toxicology, machine learning, and in vivo and in vitro experiments

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  23. Resveratrol, a red wine antioxidant, reduces atrial fibrillation susceptibility in the failing heart by PI3K/AKT/eNOS signaling pathway activation · Eric Y. Chong · 2015 · 94 citations · Cited by this paper
  24. Control of Cardiac Repolarization by Phosphoinositide 3-Kinase Signaling to Ion Channels · Lisa M. Ballou · 2014 · 94 citations · Cited by this paper
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  26. Unraveling the enigma of cardiac damage caused by lead: Understanding the intricate relationship between oxidative stress and other multifactorial mechanisms · Anjali Rajpoot · 2024 · 46 citations · Cited by this paper
  27. Management of atrial fibrillation in older adults · Anna L. Parks · 2024 · 45 citations · Cited by this paper
  28. Low-lead doses induce oxidative damage in cardiac tissue: Subacute toxicity study in Wistar rats and Benchmark dose modelling · Dragana Javorac · 2022 · 31 citations · Cited by this paper
  29. Environmental Exposome and Atrial Fibrillation: Emerging Evidence and Future Directions · Sojin Youn Wass · 2024 · 25 citations · Cited by this paper
  30. Associations of ambient air pollution with incidence and dynamic progression of atrial fibrillation · Junguo Zhang · 2024 · 17 citations · Cited by this paper
  31. Trends and Disparities in Diabetes Mellitus and Atrial fibrillation Related Mortality in the United States: 1999–2020 · Muhammad Umer Sohail · 2025 · 16 citations · Cited by this paper
  32. Effects of selenium biofortification on Pleurotus eryngii protein structure and digestive properties and its mitigation of lead toxicity: An in vitro and in vivo study · Yang Ji · 2024 · 14 citations · Cited by this paper
  33. Cross-species coherence in effects and modes of action in support of causality determinations in the U.S. Environmental Protection Agency’s Integrated Science Assessment for Lead · Meredith Gooding Lassiter · 2015 · 13 citations · Cited by this paper
  34. Lead activates neutrophil degranulation to induce early myocardial injury in mice · Yanjun Wu · 2023 · 12 citations · Cited by this paper
  35. Cardiac Toxicity Induced by Long-Term Environmental Levels of MC-LR Exposure in Mice · Canqun Yan · 2023 · 8 citations · Cited by this paper
  36. Melatonin lessens the susceptibility to atrial fibrillation in sleep deprivation by ameliorating Ca2+ mishandling in response to mitochondrial oxidative stress · Jun Shen · 2025 · 8 citations · Cited by this paper
  37. Identification and verification of FN1, P4HA1 and CREBBP as potential biomarkers in human atrial fibrillation · Miao Zhu · 2023 · 6 citations · Cited by this paper
  38. Atrial fibroblast-derived exosomal miR-21 upregulate myocardial KCa3.1 via the PI3K-Akt pathway during rapid pacing · Fu Yuntao · 2024 · 6 citations · Cited by this paper
  39. The global burden of atrial fibrillation and atrial flutter in older adults (≥ 65 years): trends, disparities, and drivers (1990–2021) · Jinglin Wang · 2025 · 6 citations · Cited by this paper

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