Research map: From Valve Anatomy to Molecular Trajectories: Integrating Proteomics into Precision Care for Bicuspid Aortic Valve Disease

Back to the article

Papers in this map

  1. 2021 ESC/EACTS Guidelines for the management of valvular heart disease · Alec Vahanian · 2021 · 5695 citations · Cited by this paper
  2. Effects of Exercise Training on Left Ventricular Hypertrophy and Cardiac Regulation in Elite Athletes: Insight from a Composite Index Proxy of Autonomic Control · 2026 · Related
  3. 2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines · Eric M. Isselbacher · 2022 · 2051 citations · Cited by this paper
  4. Clinical and Economic Implications of High-Sensitivity Troponin-Informed Admission Strategies in Non-AMI Chest Pain · 2026 · Related
  5. Incidence of Aortic Complications in Patients With Bicuspid Aortic Valves · Héctor I. Michelena · 2011 · 837 citations · Cited by this paper
  6. Real-World Safety of Acoramidis in Transthyretin Amyloid Cardiomyopathy: A Pharmacovigilance Study · 2026 · Related
  7. Clinical and Pathophysiological Implications of a Bicuspid Aortic Valve · Paul W.M. Fedak · 2002 · 802 citations · Cited by this paper
  8. Predictive Performance of the HEART Score for Acute Coronary Syndrome with Significant Coronary Stenosis in Patients with Non–ST-Elevation Acute Chest Pain · 2026 · Related
  9. Large-scale community echocardiographic screening reveals a major burden of undiagnosed valvular heart disease in older people: the OxVALVE Population Cohort Study · Joanna L D’Arcy · 2016 · 725 citations · Cited by this paper
  10. Evolving Proteomic Biomarkers in Children with Congenital Heart Defects · 2026 · Related
  11. Aortic Dilatation in Patients with Bicuspid Aortic Valve · Subodh Verma · 2014 · 509 citations · Cited by this paper
  12. Time-Cumulative Residual Cardiovascular Risk in Patients with Coronary Heart Disease and Diabetes: A 10-Year Follow-Up Study from a Large-Scale Population Cohort and an Independent Clinical Validation Cohort · 2026 · Related
  13. Valve-Related Hemodynamics Mediate Human Bicuspid Aortopathy · David G. Guzzardi · 2015 · 453 citations · Cited by this paper
  14. Feasibility of On-Site CT-FFR Analysis in Ruling Out In-Stent Restenosis on Cardiac PCCT · 2026 · Related
  15. Bicuspid Aortic Valve: Four-dimensional MR Evaluation of Ascending Aortic Systolic Flow Patterns · Michael D. Hope · 2010 · 421 citations · Cited by this paper
  16. Biomarkers of Cardiovascular Stress: A Historical Review · 2026 · Related
  17. Bicuspid Aortic Cusp Fusion Morphology Alters Aortic Three-Dimensional Outflow Patterns, Wall Shear Stress, and Expression of Aortopathy · Riti J Mahadevia · 2013 · 414 citations · Cited by this paper
  18. Neuroprognostication After Extracorporeal Cardiopulmonary Resuscitation: ECMO-Specific Challenges and a Multimodal Time-Sensitive Framework · 2026 · Related
  19. Association Between Transcatheter Aortic Valve Replacement for Bicuspid vs Tricuspid Aortic Stenosis and Mortality or Stroke · Raj Makkar · 2019 · 321 citations · Cited by this paper
  20. The American Association for Thoracic Surgery consensus guidelines on bicuspid aortic valve–related aortopathy: Full online-only version · Michael Andrew Borger · 2018 · 288 citations · Cited by this paper
  21. Aortic flow patterns and wall shear stress maps by 4D-flow cardiovascular magnetic resonance in the assessment of aortic dilatation in bicuspid aortic valve disease · José Fernando Rodríguez-Palomares · 2018 · 255 citations · Cited by this paper
  22. Transcatheter Aortic Valve Replacement With Early- and New-Generation Devices in Bicuspid Aortic Valve Stenosis · Sung Han Yoon · 2016 · 228 citations · Cited by this paper
  23. Contemporary natural history of bicuspid aortic valve disease: a systematic review · Ahmad Masri · 2017 · 212 citations · Cited by this paper
  24. Proteomics Research in Cardiovascular Medicine and Biomarker Discovery · Maggie P. Y. Lam · 2016 · 110 citations · Cited by this paper
  25. RNA expression profile of calcified bicuspid, tricuspid, and normal human aortic valves by RNA sequencing · Sandra Guauque-Olarte · 2016 · 96 citations · Cited by this paper
  26. A Proteomics-Based Approach for Prediction of Different Cardiovascular Diseases and Dementia · Frederick Ka Wing Ho · 2024 · 72 citations · Cited by this paper
  27. NOTCH Signaling in Aortic Valve Development and Calcific Aortic Valve Disease · Yidong Wang · 2021 · 54 citations · Cited by this paper
  28. Proteomic Biomarkers for Incident Aortic Stenosis Requiring Valvular Replacement · Johan Ljungberg · 2018 · 40 citations · Cited by this paper
  29. Genetic and Developmental Contributors to Aortic Stenosis · Punashi Dutta · 2021 · 39 citations · Cited by this paper
  30. Family screening for bicuspid aortic valve and aortic dilatation: a meta-analysis · Jonathan James Hyett Bray · 2023 · 39 citations · Cited by this paper
  31. Large-Scale Proteomics Identifies Novel Biomarkers and Circulating Risk Factors for Aortic Stenosis · Khaled Shelbaya · 2024 · 39 citations · Cited by this paper
  32. Speaking a common language: Introduction to a standard terminology for the bicuspid aortic valve and its aortopathy · Héctor I. Michelena · 2020 · 38 citations · Cited by this paper
  33. Multimodality imaging in bicuspid aortic valve · Laura Galián-Gay · 2020 · 28 citations · Cited by this paper
  34. Novel Polygenic Risk Score and Established Clinical Risk Factors for Risk Estimation of Aortic Stenosis · Aeron M Small · 2024 · 23 citations · Cited by this paper
  35. Bicuspid Aortic Valve Disease: From Pathophysiology to Treatment · Odysseas Katsaros · 2024 · 19 citations · Cited by this paper
  36. Effect of Denosumab or Alendronate on Vascular Calcification: Secondary Analysis of SALTIRE2 Randomized Controlled Trial · Jolien Geers · 2024 · 13 citations · Cited by this paper
  37. Excess Provisional Extracellular Matrix: A Common Factor in Bicuspid Aortic Valve Formation · Christine B. Kern · 2021 · 12 citations · Cited by this paper
  38. Anatomy-derived 3D Aortic Hemodynamics Using Fluid Physics–informed Deep Learning · Haben Berhane · 2025 · 9 citations · Cited by this paper
  39. Natural history and clinical burden of moderate aortic stenosis: a systematic review and explorative meta-analysis · Martina Morelli · 2023 · 6 citations · Cited by this paper

Source: OpenAlex (CC0)