Research map: Ganoderic acid A accelerates osteoporotic fracture healing by promoting osteogenic differentiation via estrogen receptor alpha binding

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  1. Global, regional, and national burden of bone fractures in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Disease Study 2019 · Aimin Wu · 2021 · 1312 citations · Cited by this paper
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  21. Ganoderma lucidum (Reishi) an edible mushroom; a comprehensive and critical review of its nutritional, cosmeceutical, mycochemical, pharmacological, clinical, and toxicological properties · Rizwan Ahmad · 2021 · 177 citations · Cited by this paper
  22. Hormone Therapy in Menopause: Concepts, Controversies, and Approach to Treatment · Valerie A. Flores · 2021 · 176 citations · Cited by this paper
  23. Phytoestrogens and Health Effects · Marie-Chantal Canivenc Lavier · 2023 · 160 citations · Cited by this paper
  24. Effect of osteoporosis medications on fracture healing · Vishal V. Hegde · 2015 · 151 citations · Cited by this paper
  25. Estrogen receptor α in osteocytes regulates trabecular bone formation in female mice · Shino Kondoh · 2013 · 120 citations · Cited by this paper
  26. Age-associated callus senescent cells produce TGF-β1 that inhibits fracture healing in aged mice · Jiatong Liu · 2022 · 113 citations · Cited by this paper
  27. Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery · André Mateus · 2017 · 105 citations · Cited by this paper
  28. Structural and Functional Profiling of Environmental Ligands for Estrogen Receptors · V. Delfosse · 2014 · 103 citations · Cited by this paper
  29. Rhizoma Drynariae-derived nanovesicles reverse osteoporosis by potentiating osteogenic differentiation of human bone marrow mesenchymal stem cells via targeting ERα signaling · Qing Zhao · 2024 · 94 citations · Cited by this paper
  30. Anti-osteoporosis therapy and fracture healing · Sune Larsson · 2012 · 70 citations · Cited by this paper
  31. Metformin accelerates bone fracture healing by promoting type H vessel formation through inhibition of YAP1/TAZ expression · Zhe Ruan · 2023 · 64 citations · Cited by this paper
  32. Vanillic acid restores homeostasis of intestinal epithelium in colitis through inhibiting CA9/STIM1-mediated ferroptosis · Jiahui Ni · 2024 · 62 citations · Cited by this paper
  33. Impact of osteoporosis and osteoporosis medications on fracture healing: a narrative review · Manju Chandran · 2024 · 61 citations · Cited by this paper
  34. Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells · David J. Hosfield · 2022 · 59 citations · Cited by this paper
  35. Pharmacological agents for bone fracture healing: talking points from recent clinical trials · Filippo Migliorini · 2023 · 55 citations · Cited by this paper
  36. Estrogen and estrogen receptors mediate the mechanobiology of bone disease and repair · Vivian Yan Shi · 2024 · 54 citations · Cited by this paper
  37. Fracture liaison programs · Piet Geusens · 2019 · 48 citations · Cited by this paper
  38. Syringin prevents bone loss in ovariectomized mice via TRAF6 mediated inhibition of NF-κB and stimulation of PI3K/AKT · Jingjing Liu · 2018 · 45 citations · Cited by this paper
  39. Phillyrin attenuates norepinephrine-induced cardiac hypertrophy and inflammatory response by suppressing p38/ERK1/2 MAPK and AKT/NF-kappaB pathways · Kecheng Tang · 2022 · 45 citations · Cited by this paper

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