Research map: Clinical application value of metagenomic next-generation sequencing in children with fever of unknown origin
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Papers in this map
FEVER OF UNEXPLAINED ORIGIN: REPORT ON 100 CASES
· Robert G. Petersdorf · 1961 · 1309 citations · Cited by this paper
Clinical features and nonoperative strategy for first-time infected urachal cysts in infants
· 2026 · Related
Understanding the Promises and Hurdles of Metagenomic Next-Generation Sequencing as a Diagnostic Tool for Infectious Diseases
· Patricia J. Simner · 2017 · 856 citations · Cited by this paper
Sex-stratified trends in hypoplastic left heart syndrome-related mortality among children and young adults in the United States, 1999–2024: a pre- and post-COVID-19 analysis
· 2026 · Related
RNA based mNGS approach identifies a novel human coronavirus from two individual pneumonia cases in 2019 Wuhan outbreak
· Liangjun Chen · 2020 · 608 citations · Cited by this paper
Risk factors and a predictive model for delayed extubation in children undergoing primary repair of tetralogy of Fallot: a retrospective cohort study with rigorous methodological validation
· 2026 · Related
Performance and Application of 16S rRNA Gene Cycle Sequencing for Routine Identification of Bacteria in the Clinical Microbiology Laboratory
· Deirdre L. Church · 2020 · 352 citations · Cited by this paper
Correlation analysis of cyclosporine A trough concentration with hematological and biochemical parameters: a retrospective study in pediatric aplastic anemia
· 2026 · Related
Fever of Unknown Origin
· Ghady Haidar · 2022 · 181 citations · Cited by this paper
Artificial intelligence in pediatric arrhythmias: current landscape, unique challenges, and translational perspectives
· 2026 · Related
Fever and Fever of Unknown Origin: Review, Recent Advances, and Lingering Dogma
· William F. Wright · 2020 · 156 citations · Cited by this paper
KLF1 mutation-associated congenital dyserythropoietic anemia type IV: a case report and literature review
· 2026 · Related
Metagenomic next-generation sequencing of samples from pediatric febrile illness in Tororo, Uganda
· Akshaya Ramesh · 2019 · 101 citations · Cited by this paper
Retrospective analysis of the clinical value of targeted nursing using a game-based model in children undergoing auricular reconstruction for congenital microtia
· 2026 · Related
Retrospective Validation of a Metagenomic Sequencing Protocol for Combined Detection of RNA and DNA Viruses Using Respiratory Samples from Pediatric Patients
· Sander van Boheemen · 2019 · 87 citations · Cited by this paper
Multimodal quantitative characterization and mechanistic exploration of paraspinal muscle groups in adolescent idiopathic scoliosis
· 2026 · Related
Plasma Metagenomic Next-Generation Sequencing Assay for Identifying Pathogens: a Retrospective Review of Test Utilization in a Large Children's Hospital
· Denver T. Niles · 2020 · 57 citations · Cited by this paper
Precision minimally invasive strategy for Hirschsprung’s disease: from anatomical resection to whole-cycle functional management—a review
· 2026 · Related
Evaluation of convenient pretreatment protocols for RNA virus metagenomics in serum and tissue samples
· Toon Rosseel · 2015 · 55 citations · Cited by this paper
Analysis of the interventional effects of ambroxol hydrochloride and ontelukast sodium combined with azithromycin on immune function and C-reactive protein serum expression in children with severe Mycoplasma pneumoniae pneumonia
· 2026 · Related
Prospective Cohort Study of Next-Generation Sequencing as a Diagnostic Modality for Unexplained Encephalitis in Children
· Julia C. Haston · 2019 · 54 citations · Cited by this paper
Evaluation of next-generation sequencing for the pathogenic diagnosis of children brain abscesses
· Huili Hu · 2019 · 32 citations · Cited by this paper
Update on Fever of Unknown Origin in Children: Focus on Etiologies and Clinical Approach
· Sandra Trapani · 2023 · 27 citations · Cited by this paper
Fever of unknown origin (FUO) in children: a single-centre experience from Beijing, China
· Bing Ren Hu · 2022 · 25 citations · Cited by this paper
Metagenomic next-generation sequencing helped diagnose scrub typhus without eschar: A case report
· Jing Qin Wu · 2019 · 22 citations · Cited by this paper
Rapid metagenomics for diagnosis of bloodstream and respiratory tract nosocomial infections: current status and future prospects
· Lluís Moragues-Solanas · 2021 · 21 citations · Cited by this paper
Clinical features of pediatric mucormycosis: role of metagenomic next generation sequencing in diagnosis
· Yu Zhang · 2024 · 17 citations · Cited by this paper
The Impact of mNGS Technology in the Etiological Diagnosis of Severe Pneumonia in Children During the Epidemic of COVID-19
· Changjiang Yu · 2023 · 14 citations · Cited by this paper
Fever of unknown origin
· William F. Wright · 2025 · 10 citations · Cited by this paper
High specificity of metagenomic next-generation sequencing using protected bronchial brushing sample in diagnosing pneumonia in children
· Chunyan Zhang · 2023 · 9 citations · Cited by this paper
Structured diagnostic scheme clinical experience sharing: a prospective study of 320 cases of fever of unknown origin in a tertiary hospital in North China
· Lin Jiang · 2023 · 7 citations · Cited by this paper
Deploying Metagenomics to Characterize Microbial Pathogens During Outbreak of Acute Febrile Illness Among Children in Tanzania
· Shabani Ramadhani Mziray · 2025 · 6 citations · Cited by this paper
Duration of onset, body temperature and C-reactive protein can be used to predict the results of pus culture in children with acute osteomyelitis of long bones
· Haiting Jia · 2024 · 4 citations · Cited by this paper
Detection of pathogens and epidemiological characteristics of community-acquired pneumonia in children using metagenomic next-generation sequencing
· ShiQu Deng · 2025 · 4 citations · Cited by this paper
Fever Of Unknown Origin In Children: A Five-Year Review
· Ma. Fema Cabanalan-Rivera · 2017 · 3 citations · Cited by this paper
Epidemiology and diagnostic challenges of fever of unknown origin (FUO) among adults: A multicenter retrospective study in Northern Italy
· Alessandra Mistral De Pascali · 2025 · 3 citations · Cited by this paper
Clinical application of metagenomic next-generation sequencing (mNGS) in children with suspected bloodstream infection
· Fen Pan · 2025 · 2 citations · Cited by this paper
Clinical and epidemiological characteristics of cat scratch disease in children from southwestern China: a retrospective analysis of mNGS-confirmed cases
· Shuyu Lai · 2026 · 1 citation · Cited by this paper
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