Research map: The Rectal Mucosal Myeloid Niche in HIV-1 Persistence: Reservoir Support, Viral Sequestration, and Therapeutic Opportunities
Back to the article
Papers in this map
- SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates · Hichem Lahouassa · 2012 · 852 citations · Cited by this paper
- HSV-1 US3 Hijacks Conserved Actin Regulatory Complexes to Drive F-Actin Remodeling · 2026 · Related
- Langerin is a natural barrier to HIV-1 transmission by Langerhans cells · Lot D. de Witte · 2007 · 633 citations · Cited by this paper
- Cross-Species Spillover of Tiger Frog Virus Caused Lethal Systemic Disease in Captive Geochelone sulcata: Etiology, Pathology, and Genomic Characterization · 2026 · Related
- Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis · Sebastiaan De Schepper · 2018 · 607 citations · Cited by this paper
- Drug Repurposing as a Broad-Spectrum Strategy Against Coronaviruses: Frontiers in Mechanisms and Clinical Translation · 2026 · Related
- Infectious HIV-1 assembles in late endosomes in primary macrophages · Annegret Pelchen–Matthews · 2003 · 488 citations · Cited by this paper
- Phylogeographic Structure and Molecular Evolution of Squash Leaf Curl China Virus · 2026 · Related
- Getting the “Kill” into “Shock and Kill”: Strategies to Eliminate Latent HIV · Youry Kim · 2018 · 435 citations · Cited by this paper
- Identification and Characterization of a Novel Luteovirus Infecting Hosta ventricosa Plants · 2026 · Related
- Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells · Iva A. Tchasovnikarova · 2015 · 398 citations · Cited by this paper
- Cross-Border Circulation and Molecular Surveillance of HIV-1 in the Azov and Donbas Regions: A Study of Genetic Diversity and Drug Resistance · 2026 · Related
- Macrophages in intestinal homeostasis and inflammatory bowel disease · Lizi M. Hegarty · 2023 · 352 citations · Cited by this paper
- Enterococcus Phage Abitsa: Biological Characterization, Antibiofilm Activity and Evolutionary Insights into the Genus Efquatrovirus · 2026 · Related
- In macrophages, HIV-1 assembles into an intracellular plasma membrane domain containing the tetraspanins CD81, CD9, and CD53 · Magdalena Deneka · 2007 · 337 citations · Cited by this paper
- Single-Tube Reverse Transcription–Loop-Mediated Isothermal Amplification Assay for Rapid Detection of Red-Spotted Grouper Nervous Necrosis Virus in Fish Species · 2026 · Related
- Differences in HIV Burden and Immune Activation within the Gut of HIV‐Positive Patients Receiving Suppressive Antiretroviral Therapy · Steven A. Yukl · 2010 · 300 citations · Cited by this paper
- Selective elimination of myeloid HIV reservoirs by targeting pro-survival pathways · 2026 · Related
- The integrin α 4 β 7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1 · Claudia Cicala · 2009 · 287 citations · Cited by this paper
- Regulation of Immune Homeostasis, Inflammation, and HIV Persistence by the Microbiome, Short-Chain Fatty Acids, and Bile Acids · 2023 · Related
- Tissue macrophage identity and self‐renewal · Rebecca Gentek · 2014 · 284 citations · Cited by this paper
- Human dendritic cells in cancer · Egle Kvedaraite · 2022 · 262 citations · Cited by this paper
- Mucus interaction to improve gastrointestinal retention and pharmacokinetics of orally administered nano-drug delivery systems · Deepak A. Subramanian · 2022 · 240 citations · Cited by this paper
- The HIV Reservoir in Monocytes and Macrophages · Michelle E. Wong · 2019 · 233 citations · Cited by this paper
- HIV-1 Latency in Monocytes/Macrophages · Amit Kumar · 2014 · 224 citations · Cited by this paper
- The Role of Macrophages in HIV-1 Persistence and Pathogenesis · Zita Kruize · 2019 · 209 citations · Cited by this paper
- Th17 Cells Are Preferentially Infected Very Early after Vaginal Transmission of SIV in Macaques · Daniel J Stieh · 2016 · 208 citations · Cited by this paper
- Macrophage polarization in inflammatory bowel disease · Kun Zhang · 2023 · 204 citations · Cited by this paper
- Phenotypic signatures of immune selection in HIV-1 reservoir cells · Weiwei Sun · 2023 · 201 citations · Cited by this paper
- Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells · Julia Bergild McBrien · 2020 · 200 citations · Cited by this paper
- Block-And-Lock Strategies to Cure HIV Infection · Gerlinde Vansant · 2020 · 180 citations · Cited by this paper
- Single-cell multiomics reveals persistence of HIV-1 in expanded cytotoxic T cell clones · Jack A. Collora · 2022 · 179 citations · Cited by this paper
- Macrophages in the gut: Masters in multitasking · Marcello Delfini · 2022 · 172 citations · Cited by this paper
- CARD8 is an inflammasome sensor for HIV-1 protease activity · Qiankun Wang · 2021 · 168 citations · Cited by this paper
- Brain microglia serve as a persistent HIV reservoir despite durable antiretroviral therapy · Yuyang Tang · 2023 · 161 citations · Cited by this paper
- Monocyte-derived macrophages contain persistent latent HIV reservoirs · Rebecca T. Veenhuis · 2023 · 155 citations · Cited by this paper
- Application of Pharmacokinetic-Pharmacodynamic Modeling in Drug Delivery: Development and Challenges · Huixi Zou · 2020 · 137 citations · Cited by this paper
- Distinct roles for DC-SIGN+-dendritic cells and Langerhans cells in HIV-1 transmission · Lot D. de Witte · 2007 · 126 citations · Cited by this paper
- Niche-specific functional heterogeneity of intestinal resident macrophages · Maria Francesca Viola · 2020 · 122 citations · Cited by this paper
Source: OpenAlex (CC0)