Research map: Novel Therapeutic Approaches and Alternatives to Antibiotic Therapy for Drug-Resistant Intra-Abdominal Infections

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Papers in this map

  1. Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism · Amna Hassan Sirelkhatim · 2015 · 4614 citations · Cited by this paper
  2. Integrated Genome Mining, Bacterial Co-Culture Activation, and Peptidomic Analyses Identify Antimicrobial Peptide Candidates from South American Bacteria · 2026 · Related
  3. Nucleic acid detection with CRISPR-Cas13a/C2c2 · Jonathan S. Gootenberg · 2017 · 4007 citations · Cited by this paper
  4. Exploratory Pharmacokinetic Characterization of Enrofloxacin and Ciprofloxacin in Plasma and Interstitial Fluid of Dogs: Nonlinear Mixed-Effects Modeling and PK/PD Target Attainment Analysis · 2026 · Related
  5. The Antibacterial Mechanism of Silver Nanoparticles and Its Application in Dentistry · Iris Xiaoxue Yin · 2020 · 1744 citations · Cited by this paper
  6. A New Antibacterial Protocol Based on Cymbopogon nardus (L.) Rendle Essential Oil and UV-C Radiation with Potential Application for Hatching Eggs · 2026 · Related
  7. Antimicrobial host defence peptides: functions and clinical potential · Neeloffer Mookherjee · 2020 · 1527 citations · Cited by this paper
  8. Towards Antimicrobial Formulations of Repurposed Drugs and Cationic Surfactants: Efficacy, Cytotoxicity on Human Cell Lines, and Ecotoxicity in Aquatic Models · 2026 · Related
  9. Nanomaterial-based therapeutics for antibiotic-resistant bacterial infections · Jessa Marie Makabenta · 2020 · 1420 citations · Cited by this paper
  10. Time-Dependent Degradation of Imipenem in Aqueous Solution and Its Impact on Antibacterial Activity · 2026 · Related
  11. Benefits and Risks of Bariatric Surgery in Adults · David E Arterburn · 2020 · 1234 citations · Cited by this paper
  12. Ceftazidime-Avibactam as Early Empiric Therapy for Gram-Negative Nosocomial Infections: A Risk-Stratified Empiric Use Informed by National AMR Surveillance Data 2024 · 2026 · Related
  13. Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT · Jotham Suez · 2018 · 1196 citations · Cited by this paper
  14. Antibiotic Prescribing Among Inpatients with Ophthalmic Diagnoses: A Decade of Evidence from Two Private-Sector Indian Hospitals · 2026 · Related
  15. Phage Therapy in the Postantibiotic Era · Fernando L. Gordillo Altamirano · 2019 · 1037 citations · Cited by this paper
  16. Synthesis, Antibacterial Evaluation, and Chemometric Profiling of a Vanilloid-Based Compounds Library Active Against Helicobacter pylori · 2026 · Related
  17. Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials · David Bikard · 2014 · 1017 citations · Cited by this paper
  18. Antibiotics and non-traditional antimicrobial agents for carbapenem-resistant Acinetobacter baumannii in Phase 1, 2, and 3 clinical trials · 2025 · Related
  19. Efficacy and tolerability of a cocktail of bacteriophages to treat burn wounds infected by Pseudomonas aeruginosa (PhagoBurn): a randomised, controlled, double-blind phase 1/2 trial · Patrick Jault · 2018 · 889 citations · Cited by this paper
  20. Plasma and intrapulmonary pharmacokinetics of funobactam, a novel diazabicyclooctane β-lactamase inhibitor, administered in combination with imipenem/cilastatin in healthy subjects · 2026 · Related
  21. Phage therapy: From biological mechanisms to future directions · Steffanie Ann Strathdee · 2023 · 830 citations · Cited by this paper
  22. The antimicrobial peptide SAAP-148 combats drug-resistant bacteria and biofilms · Anna de Breij · 2018 · 559 citations · Cited by this paper
  23. The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections · Massimo Sartelli · 2017 · 509 citations · Cited by this paper
  24. Effect and Safety of Meropenem–Vaborbactam versus Best-Available Therapy in Patients with Carbapenem-Resistant Enterobacteriaceae Infections: The TANGO II Randomized Clinical Trial · Richard G. Wunderink · 2018 · 460 citations · Cited by this paper
  25. Review: Lessons Learned From Clinical Trials Using Antimicrobial Peptides (AMPs) · Gabrielle S. Dijksteel · 2021 · 431 citations · Cited by this paper
  26. RESTORE-IMI 1: A Multicenter, Randomized, Double-blind Trial Comparing Efficacy and Safety of Imipenem/Relebactam vs Colistin Plus Imipenem in Patients With Imipenem-nonsusceptible Bacterial Infections · J. Motsch · 2019 · 425 citations · Cited by this paper
  27. Antibiotics in the clinical pipeline as of December 2022 · Mark S. Butler · 2023 · 245 citations · Cited by this paper
  28. Complications of bariatric surgery: Presentation and emergency management · Radwan Kassir · 2016 · 225 citations · Cited by this paper
  29. Conjugative Delivery of CRISPR-Cas9 for the Selective Depletion of Antibiotic-Resistant Enterococci · Marinelle Rodrigues · 2019 · 167 citations · Cited by this paper
  30. Complications Associated With Lateral Interbody Fusion: Nationwide Survey of 2998 Cases During the First 2 Years of Its Use in Japan · Shunsuke Fujibayashi · 2017 · 165 citations · Cited by this paper
  31. Stronger together? Perspectives on phage-antibiotic synergy in clinical applications of phage therapy · Anca Mara Segall · 2019 · 155 citations · Cited by this paper
  32. Polymeric nano- and microparticulate drug delivery systems for treatment of biofilms · Stine Egebro Birk · 2021 · 153 citations · Cited by this paper
  33. Postoperative infectious complications after pancreatic resection · Keiichi Okano · 2015 · 130 citations · Cited by this paper
  34. Cefepime–Taniborbactam in Complicated Urinary Tract Infection · Florian Wagenlehner · 2024 · 130 citations · Cited by this paper
  35. Imipenem/Cilastatin/Relebactam: A Review in Gram-Negative Bacterial Infections · Young‐A Heo · 2021 · 123 citations · Cited by this paper
  36. Chemical structure and pharmacokinetics of novel quinolone agents represented by avarofloxacin, delafloxacin, finafloxacin, zabofloxacin and nemonoxacin · Béla Kocsis · 2016 · 121 citations · Cited by this paper
  37. Eravacycline: A Review in Complicated Intra-Abdominal Infections · Lesley J. Scott · 2019 · 118 citations · Cited by this paper
  38. Secondary Peritonitis and Intra-Abdominal Sepsis: An Increasingly Global Disease in Search of Better Systemic Therapies · Thomas West Clements · 2021 · 117 citations · Cited by this paper
  39. Perioperative Probiotics or Synbiotics in Adults Undergoing Elective Abdominal Surgery · Abeed H. Chowdhury · 2019 · 110 citations · Cited by this paper

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